37 research outputs found
A Literature Review on Cloud Computing Adoption Issues in Enterprises
Part 3: Creating Value through ApplicationsInternational audienceCloud computing has received increasing interest from enterprises since its inception. With its innovative information technology (IT) services delivery model, cloud computing could add technical and strategic business value to enterprises. However, cloud computing poses highly concerning internal (e.g., Top management and experience) and external issues (e.g., regulations and standards). This paper presents a systematic literature review to explore the current key issues related to cloud computing adoption. This is achieved by reviewing 51 articles published about cloud computing adoption. Using the grounded theory approach, articles are classified into eight main categories: internal, external, evaluation, proof of concept, adoption decision, implementation and integration, IT governance, and confirmation. Then, the eight categories are divided into two abstract categories: cloud computing adoption factors and processes, where the former affects the latter. The results of this review indicate that enterprises face serious issues before they decide to adopt cloud computing. Based on the findings, the paper provides a future information systems (IS) research agenda to explore the previously under-investigated areas regarding cloud computing adoption factors and processes. This paper calls for further theoretical, methodological, and empirical contributions to the research area of cloud computing adoption by enterprises
A draft human pangenome reference
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals. These assemblies cover more than 99% of the expected sequence in each genome and are more than 99% accurate at the structural and base pair levels. Based on alignments of the assemblies, we generate a draft pangenome that captures known variants and haplotypes and reveals new alleles at structurally complex loci. We also add 119 million base pairs of euchromatic polymorphic sequences and 1,115 gene duplications relative to the existing reference GRCh38. Roughly 90 million of the additional base pairs are derived from structural variation. Using our draft pangenome to analyse short-read data reduced small variant discovery errors by 34% and increased the number of structural variants detected per haplotype by 104% compared with GRCh38-based workflows, which enabled the typing of the vast majority of structural variant alleles per sample
Catheter-Related Bloodstream Infections, Part I: Pathogenesis, Diagnosis, and Management
Bridging Trial and Decision: A Checklist to Frame Health Technology Assessments for Resource Allocation Decisions
The Polyphonic Self: Interactivism and the Examination of Culture in Clinical Sport Psychology
Despite valuable research regarding multicultural encounters in sport psychology settings, the mechanisms by which culture operates, including the ways that it is transmitted and learned, and the specific processes though which it exerts influence upon behavior, remain poorly understood. Research also has not addressed how a dimension of experience that is so fundamental could remain so transparent and reside so consistently outside the awareness of researchers, clinicians, and clients. Recent contributions to cultural psychology using an interactivist model provide a theoretical perspective through which clinical sport psychologists could conceptualize these challenging issues and address the complex behaviors observed in cross-cultural contexts. Interactivism offers a framework for investigating the internally inconsistent “polyphonic,” or multivoiced, nature of the self. In doing so, it highlights the need for investigative methods that can account for frequent discrepancies between implicit attitudes and observed behaviors, on one hand, and explicit attitudes and behaviors as endorsed on self-report measures, on the other