Estancamiento atmosférico en la región euromediterránea : variabilidad espaciotemporal e impacto en la calidad del aire

Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Físicas, leída el 22-07-2022Air stagnation occurs under stable weather conditions, weak winds in the lower tomid-troposphere and absence of precipitation. These conditions minimize the horizontal dispersion and vertical mixing of air masses as well as the scavenging of air pollutants, favouring their accumulation in the lower atmospheric layers (e.g. Leibensperger et al.,2008; Jacob and Winner, 2009; Tai et al., 2010; Dawson et al., 2014). In the last few years, several studies have developed meteorological indices to identify stagnant conditions conducive to enhanced air pollution (Wang and Angell, 1999;Horton et al., 2012, 2014; Wang et al., 2016, 2018; Cai et al., 2017; Zou et al., 2017; Feng et al., 2018, 2020; Huang et al., 2018). Despite sharing common features, such socalled air stagnation indices (ASIs) are defined based on different meteorological variables and their applicability may be geographically dependent. Most previous studies on air stagnation have either been conducted on global and hemispheric scales (Horton et al.,2012, 2014; Wang et al., 2018), or have been confined to the US (Wang and Angell, 1999; Leibensperger et al., 2008; Tai et al., 2010) or China (Huang et al., 2017, 2018; Wanget al., 2016; Zou et al., 2020). However, although southern Europe has been identified as a climate hot spot where climate models project strong increases in air stagnation frequency (Horton et al., 2014), a systematic analysis of air stagnation and its impact on air quality has not been carried out hitherto for Europe and the Mediterranean region...El estancamiento atmosférico se caracteriza por condiciones atmosféricas estables, vientos débiles en la troposfera media y baja, y ausencia de precipitación. Estas condiciones minimizan la dispersión horizontal y la mezcla vertical de masas de aire, favoreciendo la acumulación de contaminantes cerca de la superficie de la Tierra (ej. Leibensperger et al., 2008; Jacob and Winner, 2009; Tai et al., 2010; Dawson et al., 2014). En los últimos años, varios estudios han desarrollado índices meteorológicos para identificar las condiciones de estancamiento que podrían desencadenar episodios de contaminación atmosférica (Wang and Angell, 1999; Horton et al., 2012, 2014; Wang et al.,2016, 2018; Cai et al., 2017; Zou et al., 2017; Feng et al., 2018, 2020; Huang et al., 2018). Pese a compartir características comunes, estos índices se definen a partir de diferentes variables meteorológicas y su aplicabilidad podría depender del lugar. En el momento actual, la mayoría de los estudios sobre las situaciones de estancamiento se han realizado a escala global o hemisférica (Horton et al., 2012, 2014; Wang et al., 2018) o se han centrado en los Estados Unidos (Wang and Angell, 1999; Leibensperger et al., 2008; Tai et al., 2010)y China (Huang et al., 2017, 2018; Wang et al., 2016; Zou et al., 2020). Sin embargo, pese a que las proyecciones climáticas indican que el entorno Mediterráneo podría ser una delas zonas con un mayor aumento del estancamiento en el futuro (Horton et al., 2014), no se ha llevado a cabo un análisis sistemático sobre el mismo para esta región...Fac. de Ciencias FísicasTRUEunpu

Estudio de AFM del crecimiento epitaxial de rodocrosita sobre la superficie {1014} de calcita

Depto. de Mineralogía y PetrologíaFac. de Ciencias GeológicasTRUEEspaña. Ministerio de Educación y CienciaUniversidad Complutense de MadridMadrid (Comunidad Autónoma)pu

Congruency fit: beyond performance in the auto supplier industry

The effects of manufacturing strategy (MS) and technology (T) on performance have been studied separately, but few studies have examined the relationship between MS and T practices clusters that improve effectiveness when implemented jointly, and even then they do not consider possible congruency between the two. This paper develops a congruency (selection) model to test for any interconnection between said clusters, without addressing causation or their combined effect on performance. The implicit outcome is that the plant will achieve a desirable effectiveness level. Through a wide-ranging survey of auto supplier plants, two approaches are considered: 1) grouping both clusters in pairs (canonical correlation analysis); and 2) a more general selection view version, with practices from both clusters related multidimensionally and subordinated by bivariate analysis (regression) to test for any congruent pattern. Both methods find a congruent relationship between manufacturing strategy and technology practice clusters, although the second provides greater detail.Ministerio de Educación y Ciencia DPI-2006-0553

A Microservices e-Health System for Ecological Frailty Assessment Using Wearables

The population in developed countries is aging and this fact results in high elderly health costs, as well as a decrease in the number of active working members to support these costs. This could lead to a collapse of the current systems. One of the first insights of the decline in elderly people is frailty, which could be decelerated if it is detected at an early stage. Nowadays, health professionals measure frailty manually through questionnaires and tests of strength or gait focused on the physical dimension. Sensors are increasingly used to measure and monitor different e-health indicators while the user is performing Basic Activities of Daily Life (BADL). In this paper, we present a system based on microservices architecture, which collects sensory data while the older adults perform Instrumental ADLs (IADLs) in combination with BADLs. IADLs involve physical dimension, but also cognitive and social dimensions. With the sensory data we built a machine learning model to assess frailty status which outperforms the previous works that only used BADLs. Our model is accurate, ecological, non-intrusive, flexible and can help health professionals to automatically detect frailty.Ministry of Economy and Competitiveness from Spain MINECO/FEDER MAT2017-85999PEuropean Union (EU) MINECO/FEDER MAT2017-85999PRegional Government of Andalusia Research Fund from Spain A-BIO-157-UGR-1

A semi-automatic mHealth system using wearable devices for identifying pain-related parameters in elderly individuals

Background Mobile health systems integrating wearable devices are emerging as promising tools for registering pain-related factors. However, their application in populations with chronic conditions has been underexplored. Objective To design a semi-automatic mobile health system with wearable devices for evaluating the potential predictive relationship of pain qualities and thresholds with heart rate variability, skin conductance, perceived stress, and stress vulnerability in individuals with preclinical chronic pain conditions such as suspected rheumatic disease. Methods A multicenter, observational, cross-sectional study was conducted with 67 elderly participants. Predicted variables were pain qualities and pain thresholds, assessed with the McGill Pain Questionnaire and a pressure algometer, respectively. Predictor variables were heart rate variability, skin conductance, perceived stress, and stress vulnerability. Multiple linear regression analyses were conducted to examine the influence of the predictor variables on the pain dimensions. Results The multiple linear regression analysis revealed that the predictor variables significantly accounted for 27% of the variability in the affective domain, 14% in the miscellaneous domain, 15% in the total pain rating index, 10% in the number of words chosen, 14% in the present pain intensity, and 16% in the Visual Analog Scale scores. Conclusion The study found significant predictive values of heart rate variability, skin conductance, perceived stress, and stress vulnerability in relation to pain qualities and thresholds in the elderly population with suspected rheumatic disease. The comprehensive integration of physiological and psychological stress measures into pain assessment of elderly individuals with preclinical chronic pain conditions could be promising for developing new preventive strategies.R&D&i Project Ref. PID2019-109644RB-I00 funded by the Ministerio de Ciencia e Innovación / Agencia Estatal de Investigación / 10.13039/501100011033R&D&i Project Ref. B-TIC-320-UGR20 funded by Junta de Andalucía and “ERDF A way of making Europe.

NT-proBNP as predictor factor of cardiotoxicity during trastuzumab treatment in breast cancer patients

Background Trastuzumab is a drug used in HER2-positive breast cancer that increases patient survival. Due to cardiotoxicity is the most important side effect of trastuzumab treatment, cardiac monitoring should be a priority. The purpose of this study is to evaluate plasma NT-proBNP level and major cardiovascular risk factors as possible early predictors of trastuzumab-induced cardiotoxicity in HER2-positive breast cancer patients. Methods We conducted a retrospective observational study involving 66 patients with HER2-positive breast cancer treated with trastuzumab. Left ventricle ejection fraction (LVEF), NT-proBNP values, and the history of cardiovascular risk factors were collected. Cardiotoxicity was diagnosed considering a decrease of the LVEF from baseline or clinical manifestation of congestive heart failure. NT-proBNP cut-off points were considered to establish normal or abnormal values according to patient age. Results 27.3% of the patients suffered cardiotoxicity during trastuzumab treatment. Most cases were diagnosed due to the appearance of cardiac symptomatology (66.7%). Logistic regression analysis showed a significant association of diabetes mellitus (OR 5.9, 95% CI 1.2–28.5, p = 0.028) and high NT-proBNP levels (OR 22.0, 95% CI 5.7–85.4, p < 0.0001) with the development of trastuzumab-induced cardiotoxicity. Conclusion NT-proBNP levels above the upper limit of the normal range adjusted to age or diabetes mellitus seem to be associated with a higher risk of developing cardiotoxicity. However, some limitations of the present study make necessary further studies aimed to clarify whether NT-proBNP and diabetes-associated markers determinations can be useful in the monitoring of cardiotoxicity risk in breast cancer patients undergoing trastuzumab therapy.Ramon Areces Foundation, Madrid, Spai

Persistencia de muesca diastólica en la flujometría Doppler de arterias uterinas, su valor predictivo en la preclampsia y CIUR

Durante la gestación, la Flujometría Doppler nos permite estudiar la circulación útero-placentaria. Teniendo en cuenta los parámetros de velocidad de la sangre durante la sístole y la diástole, se han determinado los índices siguientes: resistencia (IR), pulsatilidad (IP) y relación sístole/diástole (S/D); generalmente el valor de estos parámetros es directamente proporcional a la resistencia inmediata al vaso evaluado, son las arterias uterinas las más frecuentemente estudiadas. Normalmente la invasión trofoblástica hacia las arterias espirales produce a nivel uteroplacentario un sistema de alta perfusión y baja resistencia. La ecografía Doppler de las arterias uterinas evalúa el éxito de esa invasión. Teniendo en cuenta el valor predictivo de esta Flujometría para las complicaciones obstétrica que derivan de una mala perfusión útero placentaria se realiza este estudio en una paciente por nuestro equipo.ABSTRACTDuring pregnancy, Doppler flowmetry allows us to study the uteroplacental circulation. Given the parameters of blood velocity during systole and diastole, they have determined the following indices: resistance, pulsatility and systole / diastole ratio; generally the value of these parameters is directly proportional to the resistance evaluated immediate glass, they are most commonly studied the uterine arteries. Normally trophoblast invasion into the spiral arteries level produced uteroplacental perfusion system high and low resistance. Doppler ultrasound of the uterine arteries evaluates the success of the invasion. Given the predictive value of this flowmetry for obstetric complications arising from poor uteroplacental perfusion study is performed on a patient by our team

The reform of spanish local governmental accounting: some critical considerations about new accounting regulation

[EN] This paper attempts to analyse from a critical perspective the recent reform of local governmental accounting in Spain, in order to identify some weak points that will need in the future further developments. This reform has been introduced by two main accounting instructions that develope the accounting standards to be applied by Spanish local authorities for financial reporting purposes. Those new standards are in force since the first of January 2015.[ES] Este artículo pretende aportar una serie de reflexiones críticas sobre la nueva regulación contable de la Administración Local recientemente introducida. El proceso de normalización contable de las administraciones públicas en España se inició hace 25 años y su última reforma ha finalizado recientemente con la nueva normativa introducida en 2015 que es objeto de estudio. En el presente trabajo, se identifican tres líneas maestras en la reforma y sus principales novedades. Su definitiva configuración merece un análisis crítico, centrado en la complejidad del sistema contable, los modelos de cuentas anuales, la necesidad de elaboración de información resumida y sintetizada, la contabilidad de costes, la consolidación de cuentas anuales, la estabilidad presupuestaria y lo que quizás resulta en los momentos actuales más inaplazable: una normativa legal que obligue a que nuestras corporaciones locales vean sus cuentas anuales auditadas externamente de forma regular y con un alcance adecuado a su propia población y presupuestoVela Bargues, JM.; Polo Garrido, F.; Pérez Yuste, MS. (2016). La reforma de la Contabilidad de la Administración Local española: algunas reflexiones crticas en torno a las nuevas instrucciones de contabilidad/. CIRIEC-España. Revista de Economía Pública, Social y Cooperativa. (86):221-250. http://hdl.handle.net/10251/74287S2212508