786 research outputs found
Flight investigation of a roll stabilized missile configuration at varying angles of attack at Mach numbers between 0.8 and 1.79
Flight Investigation of a Roll-stabilized Missile Configuration at Varying Angles of Attack at Mach Numbers Between 0.8 and 1.79
A missile research model was flown at supersonic speed to determine the quality of automatic roll stabilization at varying angles of attack. Aerodynamic rolling and pitching derivatives were determined from the flight record. It was concluded that the combination of the gyro-actuated automatic pilot with wing-tip ailerons provided adequate roll stabilization under conditions encountered in flight
Method for determining the frequency-response characteristics of an element or system from the system transient output response to a known input function
A method is presented for the determination of the frequency-response characteristics of an element or system by utilizing the transient output response to a known but arbitrary input to the system. Since the application of special inputs, such as step functions or sinusoids, is often imperfect or impractical, a method for utilizing arbitrary inputs is desirable. Simple flight-test data may be reduced by this method to give the frequency response of an aircraft. Examples are given as determinations of aircraft frequency responses; however, the method can be applied to any type of dynamic system, such as automatic-control components, vibration-absorption equipment, and many types of instruments. The method requires that the arbitrary input function tend to a finite value after a finite time and that the system or element output be measured as a representative quantity having a static sensitivity. (author
Method for determining the frequency-response characteristics of an element or system from the system transient output response to a known input function
NMR-based metabolomics: global analysis of metabolites to address problems in prostate cancer
Quality of seed produced by tropical forage legumes on low fertility soils
This study compared seed yields, seed and seedling characteristics of 8 forage legumes including Stylosanthes spp, Centrosema spp, Desmanthus spp, and Macroptilium spp grown on red and yellow kandosol soils of low fertility
Integrative Medicine in a Preventive Medicine Residency: A Program for the Urban Underserved
The Preventive Medicine Residency Program collaborated with the Department of Family Medicine\u27s Program for Integrative Medicine and Health Disparities at Boston Medical Center to create a new rotation for preventive medicine residents starting in autumn 2012. Residents participated in integrative medicine group visits and consults, completed an online curriculum in dietary supplements, and participated in seminars all in the context of an urban safety net hospital. This collaboration was made possible by a federal Health Resources and Services Administration grant for integrative medicine in preventive medicine residencies and helped meet a need of the program to increase residents\u27 exposure to clinical preventive medicine and integrative health clinical skills and principles. The collaboration has resulted in a required rotation for all residents that continues after the grant period and has fostered additional collaborations related to integrative medicine across the programs
Long-term Survival Outcomes for Men Who Provided Ejaculate Specimens for Prostate Cancer Research: Implications for Patient Management
Background: Determining whether men diagnosed with early prostate cancer (PCa) will live long enough to benefit from interventions with curative intent is difficult. Although validated instruments for predicting patient survival are available, these do not have clinical utility so are not used routinely in practice. Objective: To test the hypothesis that volunteers who provided ejaculate specimens had a high survival rate at 10 and 15 yr and beyond. Design, setting, and participants: A total of 290 patients investigated because of high serum prostate-specific antigen donated ejaculate specimens for research between January 1992 and May 2003. The median age at the time of ejaculation was 63.5 yr. 153 of the donors were diagnosed with PCa and followed up to December 31, 2013. Outcome measurements and statistical analysis: Survival outcomes were compared with those for the whole population, as indicated by life expectancy tables up to 20 yr. Results and limitations: Men in the PCa group had life expectancies comparable with values listed in life expectancy tables for the whole population. Overall, PCa-specific and relative survival were significantly better for men in the non-PCa and PCa groups in comparison with men diagnosed with PCa in Queensland during the same period. Relative survival for those aged 20-49, 50-64, and ≥65 yr was >100% for ejaculate donors and 81.5%, 82.7%, and 65.2%, respectively, for the Queensland Cancer Registry reference at 10 yr. These findings for this highly selected patient cohort support the hypothesis that an ability to provide an ejaculate specimen is associated with a high likelihood of surviving 10-20 yr after donation, whether or not PCa was detected. Conclusion: Life expectancy tables may serve as a quick and simple life expectancy indicator for biopsy patients who donate ejaculate. Patient summary: Life expectancy tables indicated survival of up to 20 yr for men who provided ejaculate specimens for prostate cancer research. Life expectancy tables indicated survival of up to 20 yr for men who provided ejaculate specimens for prostate cancer research
Timing of exercise for muscle strength and physical function in men initiating ADT for prostate cancer
© 2020, The Author(s). Background: Androgen deprivation therapy (ADT) in men with prostate cancer (PCa) results in adverse effects, including reduced muscle strength and physical function, potentially compromising daily functioning. We examined whether it was more efficacious to commence exercise at the onset of ADT rather than later in treatment to counter declines in strength and physical function. Methods: One-hundred-and-four men with PCa (68.3 ± 7.0 years) initiating ADT were randomised to immediate exercise (IMX, n = 54) or delayed exercise (DEL, n = 50) for 12 months. IMX comprised 6 months of supervised resistance/aerobic/impact exercise initiated at the onset of ADT with a 6-month follow-up. DEL comprised 6 months of usual care followed by 6 months of resistance/aerobic/impact exercise. Upper and lower body muscle strength and physical function were assessed at baseline, 6 and 12 months. Results: There was a significant difference for all strength measures at 6 months favouring IMX (P \u3c 0.001), with net differences in leg press, seated row and chest press strength of 19.9 kg (95% CI, 12.3–27.5 kg), 5.6 kg (3.8–7.4 kg) and 4.3 kg (2.7–5.8 kg), respectively. From 7 to 12 months, DEL increased in all strength measures (P \u3c 0.001), with no differences between groups at 12 months. Similarly, physical function improved (P \u3c 0.001) in IMX compared with DEL at 6 months for the 6-m fast walk (−0.2, 95% CI −0.3 to −0.1 s), 400-m walk (−9.7, −14.8 to −4.6 s), stair climb (−0.4, −0.6 to −0.2 s) and chair rise (−1.0, −1.4 to −0.7 s), with no differences between groups by 12 months, except for the 6-m fast walk (P \u3c 0.001). Conclusion: Exercise either at the onset or after 6 months of ADT preserves/enhances muscle strength and physical function. However, to avoid initial treatment-related adverse effects on strength and function, exercise therapy should be implemented with initiation of ADT
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