An Albino Mutant in Brassica rapa Maps to the PDX2 Locus on Chromosome 10

We have identified an albino mutant in the plant Brassica rapa. This recessive mutation could provide insights into the photosynthetic pathways of all plants. Previously the mutation was mapped to chromosome 10 of Brassica rapa. To narrow down the chromosomal region containing the albino mutation, we grew a segregating population of plants. DNA was extracted from albino and wildtype (green) plants and genotyped using PCR markers on chromosome 10. The genotype detected using the INDEL2 marker perfectly predicted whether a plant was albino or WT. This indicates that the INDEL2 marker is tightly linked to the albino mutation. INDEL2 is near the gene PDX2 and we detected a single nucleotide change near the PDX2 gene that is only found in albino plants. It is possible that this mutation affects the expression of PDX2 and is the cause of the albino phenotype. PDX2 is involved in vitamin B6 synthesis and it is unclear how altering vitamin metabolism could affect photosynthesis

Information consequences of accounting conservatism

We study the information consequences of conservatism in accounting. Prior research shows that information asymmetries in capital markets lead to firm-level increases in conservatism. In this paper, we further argue that increases in conservatism improve the firm information environment and lead to subsequent decreases in information asymmetries between firm insiders and outsiders. We predict and test if this decrease in information asymmetries manifests itself through: (a) a decrease in the bid-ask spread and in stock-returns volatility, and (b) an improved information environment for financial analysts, leading to more precise and less dispersed forecasts, and to more analysts following the firm. Using a large US sample for the period 1977-2007 and several proxies for conservatism we find robust evidence consistent with our expectations. Our results are in line with conservatism being useful not only for debt-holders, but also for equity-holders.We acknowledge financial assistance from the Spanish Ministry of Education and Science (ECO2010–19314, ECO2008–06238/ECON and SEJ2007-67582/ECON), the ICJCE/AT1 UAM-Auditores Madrid Chair, IESE Research Division, the Government of Comunidad de Madrid (Grant CCG10-UC3M/HUM-4760) and the AECA Chair in Accounting and Auditing

Semantic Privacy Policies for Service Description and Discovery in Service-Oriented Architecture

Privacy preservation in Service-Oriented Architecture (SOA) is an open problem. This paper focuses on the areas of service description and discovery. The problems in these areas are that currently it is not possible to describe how a service provider deals with information received from a service consumer as well as discover a service that satisfies the privacy preferences of a consumer. There is currently no framework which offers a solution that supports a rich description of privacy policies and their integration in the process of service discovery. Thus, the main goal of this paper is to propose a privacy preservation framework for the areas of service description and discovery in SOA. The framework enhances service description and discovery with the specification and intersection of privacy policies using a base and domain-specific privacy ontologies. Moreover, the framework extends SOA to include roles responsible for implementing a privacy registry as well as mediating the interactions between service consumers and providers and the privacy preservation component

An Albino Mutant in Brassica rapa Maps to the PDX2 Locus on Chromosome 10

We have identified an albino mutant in the plant Brassica rapa. This recessive mutation could provide insights into the photosynthetic pathways of all plants. Previously the mutation was mapped to chromosome 10 of Brassica rapa. To narrow down the chromosomal region containing the albino mutation, we grew a segregating population of plants. DNA was extracted from albino and wildtype (green) plants and genotyped using PCR markers on chromosome 10. The genotype detected using the INDEL2 marker perfectly predicted whether a plant was albino or WT. This indicates that the INDEL2 marker is tightly linked to the albino mutation. INDEL2 is near the gene PDX2 and we detected a single nucleotide change near the PDX2 gene that is only found in albino plants. It is possible that this mutation affects expression of PDX2 and is the cause of the albino phenotype. PDX2 is involved in vitamin B6 synthesis and it is unclear how altering vitamin metabolism could affect photosynthesis

Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas

The influence of common tea preparation procedures (temperature, infusion time, consumption time interval and tea bag/loose-leaf) and the type of water used, on the total phenolic content (TPC), the radical scavenging activity and the alpha-glucosidase inhibitory activity were assessed. Higher TPC and antioxidant activity were obtained when using lower mineralized waters. Tea bags also evidenced higher antioxidant activity than loose-leaf samples. Under the same conditions (90 degrees C and five minutes of infusion time) green tea contains almost twice the quantity of polyphenols and the free radical scavenging ability of black tea. In the alpha-glucosidase assay all infusions were active (97-100 %). Furthermore, HPLC allowed to identify some of the polyphenols present in both teas and to monitor their composition change with time. After twenty-four hours, the antioxidant activity was maintained without significant changes, but a small decrease in enzyme inhibition was observed, although this activity was still very high.info:eu-repo/semantics/publishedVersio

Association between anxiety and vascular dementia risk: new evidence and an updated meta-analysis

The association between anxiety and vascular dementia (VaD) is unclear. We aimed to reliably estimate the association between anxiety and VaD risk using meta-analysis to pool new results from a large community-based cohort (Zaragoza Dementia and Depression (ZARADEMP) study) and results from previous studies. ZARADEMP participants (n = 4057) free of dementia were followed up on for up to 12 years. Cases and subcases of anxiety were determined at baseline. A panel of four psychiatrists diagnosed incident cases of VaD by consensus. We searched for similar studies published up to October 2019 using PubMed and Web of Science. Observational studies reporting associations between anxiety and VaD risk, and adjusting at least for age, were selected. Odds ratios (ORs) from each study were combined using fixed-effects models. In the ZARADEMP study, the risk of VaD was 1.41 times higher among individuals with anxiety (95% CI: 0.75-2.68) compared with non-cases (p = 0.288). Pooling this result with results from two previous studies yielded an OR of 1.65 (95% CI: 1.07-2.53; p = 0.022). These findings indicate that anxiety is associated with an increased risk of VaD. Taking into account that anxiety is commonly observed in the elderly, treating and preventing it might reduce the prevalence and incidence of VaD. However, whether anxiety is a cause of a prodrome of VaD is still unknown, and future research is needed to clarify this

Estudio de diferentes protocolos de restricción alimentaria sobre el desarrollo fetoplacentario en la coneja

Two feed strategies (ad libitum throughout pregnancy and restriction during the first 20 days), combined with oestrus synchronization with eCG or not in nulliparous rabbit does, were studied

Steady-state total diffuse reflectance with an exponential decaying source

The increasing preclinical and clinical utilization of digital cameras for photographic measurements of tissue conditions motivates the study of reflectance measurements obtained with planar illumination. We examine herein a formula that models the total diffuse reflectance measured from a semi-infinite medium using an exponentially decaying source, assuming continuous plane wave epi-illumination. The model is validated with experimental reflectance measurements from tissue mimicking phantoms. The need for adjusting the blood absorption spectrum due to pigment packaging is discussed along with the potential applications of the proposed formulation.This research PBGA was supported in part by a Marie Curie Intra European Fellowship within the 7th European Community Framework Program. J. R. acknowledges a Marie Curie CIG grant