153 research outputs found

    Preparation of ultra-porous UPM/PHBV nanofibres using solvent-etching technology and drug-loading efficiency

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    In this study, ultra-porous fibres have been produced by partly washing out poly(3-hydroxybutyrateco-3-hydroxyvalerate) (PHBV) from the heat-crosslinked electrospun unsaturated polyester macromonomers/poly(3-hydroxybutyrateco-3-hydroxyvalerate) (UPM/PHBV) fibrous composite using chloroform. Tetracycline hydrochloride has been used as the module drug to test the drug-loading efficiency of porous fibres. Field emission scanning electron microscope images show that the etched UPM/PHBV fibres have lost the original smooth surface. The result demonstrates that the PHBV is successfully washed by chloroform, but most of UPM is remained because of the heat-crosslinking. Furthermore, with the increase of PHBV ratio in composite fibres, the etched fibres show much rougher surface. The drug absorption behavior also varies with the different PHBV ratios

    FHT-Map: Feature-based Hierarchical Topological Map for Relocalization and Path Planning

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    Topological maps are favorable for their small storage compared to geometric map. However, they are limited in relocalization and path planning capabilities. To solve this problem, a feature-based hierarchical topological map (FHT-Map) is proposed along with a real-time map construction algorithm for robot exploration. Specifically, the FHT-Map utilizes both RGB cameras and LiDAR information and consists of two types of nodes: main node and support node. Main nodes will store visual information compressed by convolutional neural network and local laser scan data to enhance subsequent relocalization capability. Support nodes retain a minimal amount of data to ensure storage efficiency while facilitating path planning. After map construction with robot exploration, the FHT-Map can be used by other robots for relocalization and path planning. Experiments are conducted in Gazebo simulator, and the results demonstrate that the proposed FHT-Map can effectively improve relocalization and path planning capability compared with other topological maps. Moreover, experiments on hierarchical architecture are implemented to show the necessity of two types of nodes.Comment: 8 pages, 7figures, 2 table

    PATTERN RELATED ISSUES IN THE MODELLING OF DEFORMED OVER SURFACE WARP KNITTED STRUCTURES WITH LONGER UNDERLAPS

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    The yarn level modelling of warp knitted structures is a complex process. For structures placed on the plane, it is well investigated and there are a few software solutions and papers reported. This paper considers the simulation of warp knitted structure, deformed in the 3D space. Especially the modelling of the areas of high curvature are detailed observed. Underlaps with longer lengths makes an unreal visualization for simulation results. Different pattern with different length of the underlaps are modelled with original algorithm developed by the authors. Modelling and visualization problems in the areas with long underlaps are discussed and possible solutions are proposed

    Measured and perceived impacts of evidence-based leadership in nursing: a mixed-methods systematic review protocol

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    Introduction Despite the abundance of existing literature on evidence-based nursing practice, knowledge regarding evidence-based leadership, that is, leadership supported by an evidence-based approach, is lacking. Our aim is to conduct a mixed-methods systematic review with qualitative and quantitative studies to examine how evidence is used to solve leadership problems and to describe the measured and perceived effects of evidence-based leadership on nurses and nurse leaders and their performance as well as on organisational and clinical outcomes. Methods and analysis We will search the following databases with no year limit or language restrictions: CINAHL (EBSCO), Cochrane Library, Embase (Elsevier), PsycINFO (EBSCO), PubMed (MEDLINE), Scopus (Elsevier) and Web of Science. In addition, the databases for prospectively registered trials and other systematic reviews will be screened. We will include articles using any type of research design as long as the study includes a component of an evidence-based leadership approach. Three reviewers will independently screen all titles, abstracts and full-text articles and two reviewers will extract the data according to the appropriate checklists. The quality of each study will be appraised using specific appraisal tool fitting in study design used in each study. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) grid, PRISMA Protocols, Synthesis Without Meta-analysis and ENTREQ will guide the study process and reporting. Outcomes related to individual or group performance of nurses or nurse managers regarding leadership skills (e.g., communication skills), organisational outcomes (e.g., work environment, costs) and clinical outcomes (e.g., patient quality of life, treatment satisfaction) will be extracted and synthesised. Ethics and dissemination This systematic review will not include empirical data, and therefore, ethics approval will not be sought. The results of the review will be disseminated in a peer-reviewed scientific journal and in a conference presentation. PROSPERO registration number CRD42021259624.</p

    Preparation of ultra-porous UPM/PHBV nanofibres using solvent-etching technology and drug-loading efficiency

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    430-433In this study, ultra-porous fibres have been produced by partly washing out poly(3-hydroxybutyrateco-3-hydroxyvalerate) (PHBV) from the heat-crosslinked electrospun unsaturated polyester macromonomers/poly(3-hydroxybutyrateco-3-hydroxyvalerate) (UPM/PHBV) fibrous composite using chloroform. Tetracycline hydrochloride has been used as the module drug to test the drug-loading efficiency of porous fibres. Field emission scanning electron microscope images show that the etched UPM/PHBV fibres have lost the original smooth surface. The result demonstrates that the PHBV is successfully washed by chloroform, but most of UPM is remained because of the heat-crosslinking. Furthermore, with the increase of PHBV ratio in composite fibres, the etched fibres show much rougher surface. The drug absorption behavior also varies with the different PHBV ratios
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