17 research outputs found

    Oesterbanken en koralen kunnen terugkeren in de Noordzee

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    De problematiek van het DEKKMMA-project

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    Annelid genomes : Enchytraeus crypticus, a soil model for the innate (and primed) immune system

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    Enchytraeids (Annelida) are soil invertebrates with worldwide distribution that have served as ecotoxicology models for over 20 years. We present the first high-quality reference genome of Enchytraeus crypticus, assembled from a combination of Pacific Bioscience single-molecule real-time and Illumina sequencing platforms as a 525.2 Mbp genome (910 gapless scaffolds and 18,452 genes). We highlight isopenicillin, acquired by horizontal gene transfer and conferring antibiotic function. Significant gene family expansions associated with regeneration (long interspersed nuclear elements), the innate immune system (tripartite motif-containing protein) and response to stress (cytochrome P450) were identified. The ACE (Angiotensin-converting enzyme) - a homolog of ACE2, which is involved in the coronavirus SARS-CoV-2 cell entry - is also present in E. crypticus. There is an obvious potential of using E. crypticus as a model to study interactions between regeneration, the innate immune system and aging-dependent decline. Enchytraeus crypticus is a soil-dwelling annelid worm that has been used over the past two decades as an ecotoxicology model. Here, Monica Amorim and colleagues present the first genome for E. crypticus. The authors identify a number of expanded gene families, including several involved with innate immunity

    A framework for flexible querying and mining of musical audio archives

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    In this paper the outline of a framework for the handling of flexible querying and mining of musical audio archives is presented. This framework has been designed within the scope of the DEKKMMA-project, which aims to build a digital musical audio archive for the ethnomusicological department of the Belgian Royal Museum for Central Africa. This museum holds one of the largest and world wide most important collections of music from Central Africa. Beside the digitizing and recording aspects, efficient access facilities for both specialized and nonspecialized users are required. In order to achieve this, the framework supports and integrates flexible querying, classification and object comparison mechanisms
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