305 research outputs found
Postbuckling Behaviour of Anisotropic Laminated Composite Plates due to Shear Loading
This study investigates postbuckling behaviour of laminated composite plates using a nine-noded shear flexible quadrilateral plate element. The formulation includes nonlinear strain-displacement relation based on von Karman's assumption. The nonlinear governing equations are solved through iteration. A detailed parametric study is carried out to bring out the influence of ply-angle, aspect ratio and material properties on the postbuckling strength of laminates due to in-plane shear loads
Management of lateral end clavicle fractures-using lateral clavicle locking plate: a prospective study
Background: Lateral end clavicle fractures are one of the common upper limb fractures. They constitute 21–28% of all clavicle fractures. Of these 10–52% is displaced fractures. The management of fractures of lateral end clavicle remains debated and challenging. The objectivbe of this study is to evaluate the functional outcome following surgical treatment of unstable/displaced (Neer type II lateral clavicle fractures, and acromio-clavicular joint dislocations Rockwood grade III to V) lateral end clavicle fractures using lateral clavicle locking plate.Methods: It is a prospective study conducted in the orthopaedics department of GSL Medical College and General Hospital for a period of 3 years (April 2016 to March 2019) among a total of 60 patients.Results: About 23 (38.3%) belonged to 41–50 years age group, followed by 16 (26.7%) to 31–40 years age group and 13 (21.7%) to >51 years age group and 8 (13.3%) to 18–30 years age group. The time from trauma to surgery ranged from 0-15 days with a mean of 5 days and the mean operating time was 41 minutes ranging between 23-70 minutes. Mean duration to union was 13.33±2.126 weeks and the mean Constant Murley score was 88.56. Functional outcome at 6 months follow up was excellent in 8 (13.3%), good in 37 (61.7%), fair in 13 (21.7%) and poor in 2 (3.3%) patients.Conclusions: Although there is no consensus as to a “gold standard” fixation method for unstable distal clavicle fractures, satisfactory outcomes could be obtained using the lateral clavicle locking plate resulting in sufficient stabilization and good functional outcome
Groundwater quality assessment by Water quality index (WQI) and Multivariate statistical analysis (MSA) for coastal zones of Srikakulam district, Andhra Pradesh
Groundwater is a vital resource for the drinking water supply to the people in the areas residing in the coastal zones. Rapid industrialization increased the human population, and anthropogenic activities led to groundwater pollution. The water quality should be continuously monitored to analyse the suitability of the water, and it is only possible by the water quality index. In the current study, we attempted to determine the groundwater quality of the Mandal headquarters of the coastal zones of the Srikakulam district, Andhra Pradesh, by using the water quality index (WQi) considering the parameters pH, Electrical conductivity, Total Dissolved Solids, Total Hardness, calcium and magnesium, potassium, and sodium, human health assessment tool, and multivariate statistical analysis. The results found that the WQi of the coastal zones ranged from 49.6 to 361.7, and in the post-monsoon season, the Etcherla Mandal station water was not advisable for drinking. Human health risk assessment showed that children in these sampling stations are more prone to the non-carcinogenic health risks associated with nitrate pollution. Proper reduction measures in the sampling areas must be taken to depreciate nitrate and seepage into the groundwater. Piper plots and correlation matrices showed the anion-cation interaction, and the principal component analyzed and showed the pollution sources. The current study concluded that anthropogenic activities continuously deteriorate groundwater quality, indirect saltwater intrusion was identified, and groundwater treatment is necessary before consumption.
Intractable hypoglycemia in pregnancy
Insulinomas are rare tumours developed from pancreatic beta cells; 27 cases of insulinoma associated with pregnancy have been reported till date, mostly diagnosed before the 16th week. Triad of insulinoma; hypoglycemic symptoms, plasma glucose < 3.0 mmol/L, symptomatic relief with glucose administration. 28-year-old primi presented to us at 29 weeks with high BP and neuroglycopenic symptoms. Repeated episodes of loss of consciousness with hypoglycemia since 14 weeks. On evaluation diagnosed to have insulinoma and managed conservatively with dietary modifications, and medical treatment. She failed to respond and pregnancy was terminated due to high BP, hypoglycemia and Doppler changes. Delivered a stillborn girl at 31 weeks. Underwent laparotomy post-delivery for enucleation of the lesion. Quick normalization of sugar levels and overall recovery remarkable. Patient is on regular follow up. Insulinoma is a rare cause of severe repeated episodes of hypoglycemia early in pregnancy
Chemotherapy of bacterial infections. Part VIII. Synthesis of carboxylic acid derivatives of 2-sulphanilamidothiazole
This article does not have an abstract
BUCKLING ANALYSIS OF AIRCRAFT STIFFENED PANEL CYLINDRICAL SHELLS
For past decades devolopment of composite material had brought tremendous change in AirFrames and Missiles. Due to composite stiffened panels implementation speed, distance and life of the Airframes and missiles had increased. During integration the composite cylindrical shell structure is provided with cutouts which reduce the strength of composite cylindrical shell and are porne to buckling. By adding Reinforcement around cutout will lead to improvement of strength. Generally T-section and I-section stiffened panel are used, but there is a disadvantage of using T-section, it can’t resist to deformation. So we designed an I-section stiffened panel (because I-section is more resistant to deformation) in CATIA and analysis in ANSYS. We considered three types of analysis in ANSYS, Modal analysis, Static analysis, Harmonic analysis respectively and also we considered two materials, one is aluminum and the other is carbon fiber. Aluminum is the common element used in the design of aircraft, but Carbon fiber is recently being used in aircrafts
Comparison of outcomes of salvage robot-assisted laparoscopic prostatectomy for post-primary radiation vs focal therapy
Objectives: To compare salvage robot-assisted laparoscopic prostatectomy (RALP) outcomes in patients who underwent radiation and those who underwent focal ablation as primary therapies. Patients and Methods: We evaluated 126 patients who underwent salvage RALPbetween 2008 and 2018. Of these, 94 (74.6%) received radiation and 32 focal ablation (25.4%) as primary therapy. These groups were compared with regard to clinical, oncological and functional outcomes. Kaplan–Meier curves and regression models were used to identify survival estimations and their predictors. Results: Before surgery, more patients were potent in the focal ablation group compared to the radiation group (46.9% vs 22.6%; P = 0.013). Peri-operative characteristics and complication rates were not significantly different between the two groups. Postoperative catheterization duration was shorter in the focal ablation group (mean 10 vs 16 days; P = 0.018). At final pathology, the focal ablation group had higher non-organ-confined disease (71% vs 50%; P = 0.042) and positive surgical margin (PSM) rates (43.8% vs 17%; P = 0.004) as compared to the radiation group; however, 5-year biochemical recurrence (BCR)-free survival rates were similar (59% vs 56%; P = 0.761). Postoperative 1-year full (no pads/day) and social (0–1 pad/day) continence rates were significantly higher in the focal ablation as compared to the radiation group (77.3% vs 39.2%, P = 0.002, and 87.5% vs 51.3%, P = 0.002, respectively). Multivariate analyses showed primary focal ablation and nerve-sparing to be predictors of postoperative continence. Erectile function was preserved in 13% and 27% of preoperatively potent patients in the radiation and focal ablation groups, respectively (P = 0.435). No predictors were identified for postoperative potency. Conclusions: Radiation was associated with inferior functional outcomes after salvage RALP. Focal therapies were associated with higher non-organ-confined disease and PSMrates, with no significant difference in short-term BCR-free survival
FLUKA Monte Carlo for Basic Dosimetric Studies of Dual Energy Medical Linear Accelerator
General purpose Monte Carlo code for simulation of particle transport is used to study the basic dosimetric parameters like percentage depth dose and dose profiles and compared with the experimental measurements from commercial dual energy medical linear accelerator. Varian Clinac iX medical linear accelerator with dual energy photon beams (6 and 15 MV) is simulated using FLUKA. FLAIR is used to visualize and edit the geometry. Experimental measurements are taken for 100 cm source-to-surface (SSD) in 50 × 50 × 50 cm3 PTW water phantom using 0.12 cc cylindrical ionization chamber. Percentage depth dose for standard square field sizes and dose profiles for various depths are studied in detail. The analysis was carried out using ROOT (a DATA analysis frame work developed at CERN) system. Simulation result shows good agreement in percentage depth dose and beam profiles with the experimental measurements for Varian Clinac iX dual energy medical linear accelerator
- …