4,042 research outputs found

    Supernova neutrino physics with a nuclear emulsion detector

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    The existence of the coherent neutrino-nucleus scattering reaction requires to evaluate, for any detector devoted to WIMP searches, the irreducible background due to conventional neutrino sources and at same time, it gives a unique chance to reveal supernova neutrinos. We report here a detailed study concerning a new directional detector, based on the nuclear emulsion technology. A Likelihood Ratio test shows that, in the first years of operations and with a detector mass of several tens of tons, the observation of the supernova signal can be achieved. The determination of the distance of the supernova from the neutrinos and the observation of 8^8B neutrinos are also discussed.Comment: 22 pages, 12 figure

    Birds of a Feather Flock Together: The Inclusive Effect of Similarity Patterns in Equity Crowdfunding

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    Crowdfunding is helping to drive financial inclusion by expanding the availability of funds to traditionally excluded and underserved groups of individuals, such as ethnic minority and female entrepreneurs. This study verifies how ethnic and gender similarity between investor and entrepreneur can affect the invested amount in an equity crowdfunding campaign. Using an integrated approach with linear regression and Shapley decomposition, we analyze 8600 investments made by 5996 unique personal shareholder investors in 81 equity crowdfunding campaigns. Results show that similarity patterns seem to significantly influence the amount invested in a campaign but their effects change according to investor’s gender and ethnic origin. In fact, even if female investors give a higher amount to men-led companies, their preference changes if the company is run by a female founder belonging to the same ethnic minority group. Results emphasize equity crowdfunding’s potential as a tool for the financial inclusion of ethnic minority groups of investors and entrepreneurs

    Effects of herd origin, AI stud and sire identification on genetic evaluation of Holstein Friesian bulls

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    The purpose of this study was to estimate the effects of herd origin of bull, AI stud and sire identification number (ID) on official estimated breeding values (EBV) for production traits of Holstein Friesian proven bulls. The data included 1,005 Italian Holstein-Friesian bulls, sons of 76 sires, born in 100 herds and progeny tested by 10 AI studs. Bulls were required to have date of first proof between September 1992 and September 1997, to be born in a herd with at least one other bull and to have sire and dam with official EBV when bull was selected for progeny testing. Records of sires with only one son were also discarded. The dependent variable analyzed was the official genetic evaluation for a “quantity and quality of milk” index (ILQ). The linear model to predict breeding values of bulls included the fixed class effects of herd origin of bull, AI testing organization, birth year of bull, and estimated breeding values of sire and dam, both as linear covariates. The R2of the model was 45% and a significant effect was found for genetic merit of sire (P < 0.001) and dam (P < 0.014), for herd origin of bull (P < 0.01) and for birth year of bull (P < 0.001). The effect of AI testing organization was not sig- nificant. The range of herd origin effect was 872 kg of ILQ. However, in this study, the causes of this result were not clear; it may be due to numerous factors, one of which may be preferential treatment on dams of bulls. Analyses of resid- uals on breeding value of proven bulls for ILQ showed a non significant effect of sire ID, after adjusting for parent aver- age, herd origin effect and birth year effect. Although the presence of bias in genetic evaluation of dairy bulls is not evi- dent, further research is recommended firstly to understand the reasons of the significant herd origin effect, secondly to monitor and guarantee the greatest accuracy and reliability of genetic evaluation procedures

    A Survey on Feedlot Performance of Purebred and Crossbred European Young Bulls and Heifers Managed Under Intensive Conditions in Veneto, Northeast Italy

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    This study, based on a nearly 10-year collection of performance data of young bulls and beef heifers, aimed to benchmark production traits of specialized fattening herds of northern Italy and to compare the performance of stock calves belonging to several European genetic types (GT). Data originated from 2806 batches (a group of stock calves homogeneous for GT, origin, finishing herd, fattening period, and diets), and concerned 188,891 animals of 10 GT herded in 44 farms of the Veneto region. For each batch, average body weight (BW) at arrival and at sale, duration of the fattening period, losses due to injury or death, purchase and sell price were collected, and average daily gain (ADG) and net sale gain (NSG) per head, per day of fattening, and per kg of BW gain were computed. Charolais and Limousine young bulls accounted for nearly 50% and 20%, respectively, of all animals, and over 90% of calves originated from France. Average BW at arrival and at slaughter approximated 370 and 650 kg, respectively, and ADG approached 1.30 kg/d, but variation due to GT was large (P<0.01). Charolais young bulls were the heaviest at slaughter and showed the greatest ADG, whereas Irish crosses produced the highest NSG per head and per day of fattening. Year affected all traits (P<0.01), but his magnitude was limited for BW at purchase or sale and for ADG, and slightly larger for NSG, even if this last trait did not evidence any long period congruent trend

    The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production

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    In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many others still deserve further investigations. In this regard, the possible role of many small open reading frames (smORFs) in actinomycete morpho-physiological differentiation is still elusive. In Streptomyces coelicolor, inactivation of the smORF trpM (SCO2038) – whose product modulates L-tryptophan biosynthesis – impairs production of antibiotics and morphological differentiation. Indeed, it was demonstrated that TrpM is able to interact with PepA (SCO2179), a putative cytosol aminopeptidase playing a key role in antibiotic production and sporulation. In this work, a S. coelicolor trpM knock-in (Sco-trpMKI) mutant strain was generated by cloning trpM into overexpressing vector to further investigate the role of trpM in actinomycete growth and morpho-physiological differentiation. Results highlighted that trpM: (i) stimulates growth and actinorhodin (ACT) production; (ii) decreases calcium-dependent antibiotic (CDA) production; (iii) has no effect on undecylprodigiosin production. Metabolic pathways influenced by trpM knock- in were investigated by combining two-difference in gel electrophoresis/nanoliquid chromatography coupled to electrospray linear ion trap tandem mass spectrometry (2D- DIGE/nanoLC-ESI-LIT-MS/MS) and by LC-ESI-MS/MS procedures, respectively. These analyses demonstrated that over-expression of trpM causes an over-representation of factors involved in protein synthesis and nucleotide metabolism as well as a down-representation of proteins involved in central carbon and amino acid metabolism. At the metabolic level, this corresponded to a differential accumulation pattern of different amino acids – including aromatic ones but tryptophan – and central carbon intermediates. PepA was also down-represented in Sco-trpMKI. The latter was produced as recombinant His-tagged protein and was originally proven having the predicted aminopeptidase activity. Altogether, these results highlight the stimulatory effect of trpM in S. coelicolor growth and ACT biosynthesis, which are elicited through the modulation of various metabolic pathways and PepA representation, further confirming the complexity of regulatory networks that control antibiotic production in actinomycetes

    The QUAX proposal: a search of galactic axion with magnetic materials

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    Aim of the QUAX (QUaerere AXion) proposal is to exploit the interaction of cosmological axions with the spin of electrons in a magnetized sample. Their effect is equivalent to the application of an oscillating rf field with frequency and amplitude which are fixed by axion mass and coupling constant, respectively. The rf receiver module of the QUAX detector consists of magnetized samples with the Larmor resonance frequency tuned to the axion mass by a polarizing static magnetic field. The interaction of electrons with the axion-equivalent rf field produces oscillations in the total magnetization of the samples. To amplify such a tiny field, a pump field at the same frequency is applied in a direction orthogonal to the polarizing field. The induced oscillatory magnetization along the polarizing field is measured by a SQUID amplifier operated at its quantum noise level.Comment: 5 pages, Contribution for the proceedings of the TAUP2015, International Conference on Topics in Astroparticle and Underground Physics, 7-11 September 2015, Torino, Ital

    The contributions of an airport and related road network to Pseudevernia furfuracea bioaccumulation of trace elements and polycyclic aromatic hydrocarbons

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    Abstract The use of a high-density lichen transplant network together with quantitative wind relationships (WQRs) made it possible to evaluate the influence of an airport and surrounding road network on the spatial variation of polycyclic aromatic hydrocarbons (PAHs) and trace elements at both the local and whole study area scale. WQRs clearly showed that the parking/idling/taxiing area (PIT), but not the landing/take-off zones (LTZs), as well as the north/north-east part of the road network were contributors at the whole study area scale to the spatial variation of elements like Ni, Mo and V, i.e. those associated with ultrafine particles due to their involvement in anti-wear materials, and of total PAHs. In the case of an airport, such a result can have strong management implications. Traffic also affected the concentration of the prevailing volatile organic compounds. In contrast, LTZs and high traffic density values were correlated with peaks of Zn, Mo, Cu, Co, Mn, Ni, V, Al and Sb when associated with coarse particulate matter generated by deterioration of the landing gear, fuselage, wings, runway asphalt and brakes. The remarkable percentage of high-speed winds strongly affected both the spatial distribution of anthropogenic emissions and their atmospheric dilution, resulting in a rather low level of contamination. Our results suggest that biomonitoring can be much improved when matched with WQRs and that, in the event of high wind speeds, PAHs associated with the gas phase and fine/ultrafine particles are effective contamination tracers mainly at the whole study area scale whereas trace elements reveal contamination patterns at both scales

    Milk coagulation traits and cheese yields of purebred Holsteins and 4 generations of 3-breed rotational crossbred cows from Viking Red, Montbéliarde, and Holstein bulls.

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    ABSTRACT Crossbreeding is a strategy to counter the declining fertility, resilience, and longevity of purebred Holstein (Ho) cows. However, little is known of the effects of long-term systematic rotational crossbreeding on milk technological properties and cheese yield (CY). In this study, we compared the individual milk composition, milk coagulation properties (MCP), and CY of 468 purebred Ho and 648 crossbred (CR) cows obtained from two 3-breed rotational crossbreeding systems using Viking Red (VR), Montbeliarde (Mo), and Ho sires over 4 generations. Individual milk samples were collected once from 1,116 primiparous and multiparous cows kept in 2 dairy herds, raised for the production of Grana Padano (high milk yield, total mixed ration based on corn silage) and Parmigiano Reggiano (moderate milk yield, only dry feeds) cheeses. In both herds, a 3-breed rotational mating system was used in which Ho cows were first inseminated with VR, whereas Mo and Ho semen was used in the subsequent generations. In one herd, the sequence Mo-VR-Ho was also used. Individual milk samples were analyzed for milk composition, single-point MCP, and parameters for modeling curd firming over time, whereas CY and milk nutrient recovery in the curd were assessed through a laboratory cheese-making procedure. Compared with Ho, CR cows produced 5.8% less milk, which had comparable fat but greater protein and casein contents and lower lactose contents and somatic cell scores. Milk from CR cows tended to reach a curd firmness of 20 mm more quickly and exhibited greater curd firmness at 45 and 60 min from rennet addition. Holstein and CR cows yielded milk with similar CY and recovery in the curd traits. The milk fat content, somatic cell scores, curd firmness traits, and CY of CR cows relative to the Ho cows differed in the 2 herds, and the favorable effects on the CR cows were more evident in the herd with the greatest milk yield and the worst MCP traits. Crossbred cows of the 4 generations performed similarly, with the exception of the better MCP of the milk from first-generation CR cows. The 2 rotational systems using different sire-breed sequences also performed similarly. In summary, both rotational crossbreeding programs exhibited some advantage over the Ho purebred breeding system in terms of milk composition and MCP but not CY. Future research is needed to investigate the interactions between crossbreeding schemes and dairy systems

    A modular modelling approach to stochastic simulation of production – logistic systems

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    The economic scenario today is highly competitive in terms of costs and number of competitors, so it isnecessary to adopt strategies that allow the constant improvement of manufacturing processes withinthe spending constrains. Simulation models are useful to support and drive company management inimproving the performances of production and logistic systems. The costs of simulation modeldevelopment could be reduced by the reuse of some of its parts. This work presents a case studyconcerning stochastic modeling of a small manufacture operating into the wood products field. Amodular simulation model composed of reusable sub-models has been developed using AutoMod™software package. The aim of the modular architecture is to allow the use of sub-models in differentproduction systems with little changes, decreasing the costs of development in order to became moreaffordable in a SME (small medium enterprise) contest
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