ANISOTROPY EXAMINATION OF MATERIALS USED IN VEHICLES CONSTRUCTION

Deformation of metals has an effect - among others - on their mechanical properties, however at the same time, it also renders these properties direction-dependent. The stress calculation of vehicles takes place for dynamic and fatigue loads, therefore it is advisable to determine for what loads and to what extent the direction-dependence is to be taken into consideration

Agronomical and phytochemical investigation of Hyssopus officinalis

Hyssop (Hyssopus officinalis L.) obtained from various commercial sources was grown for three years (1990-1992) in Finland. Yield characteristics, flower colour, volatile oil content/composition and its antimicrobial quality were studied. For comparison, Scottish-grown hyssop was included in oil and quality determinations. The description of the flower colour given by the seed firms was not a reliable indicator of the true colour in many cases. Oil yield was satisfactory and oil composition was rather uniform. Only one different chemotype was identified, this was derived from a Romanian seed source. There was considerable variation in herb yield between plants from different sources. The total fresh herb yield was 0.5-3.2 kg/m2, the dry leaf yield was 67-326 g/m2. Seed germination was satisfactory (76-99%), offering opportunities for seed production of varieties with different characteristics

Risk of thrombosis and bleeding in gynecologic cancer surgery: systematic review and meta-analysis

Objective: This study aimed to provide procedure-specific estimates of the risk of symptomatic venous thromboembolism and major bleeding in the absence of thromboprophylaxis, following gynecologic cancer surgery.Data sources: We conducted comprehensive searches on Embase, MEDLINE, Web of Science, and Google Scholar for observational studies. We also reviewed reference lists of eligible studies and review articles. We performed separate searches for randomized trials addressing effects of thromboprophylaxis and conducted a web-based survey on thromboprophylaxis practice.Study eligibility criteria: Observational studies enrolling ≥50 adult patients undergoing gynecologic cancer surgery procedures reporting absolute incidence for at least 1 of the following were included: symptomatic pulmonary embolism, symptomatic deep vein thrombosis, symptomatic venous thromboembolism, bleeding requiring reintervention (including reexploration and angioembolization), bleeding leading to transfusion, or postoperative hemoglobin <70 g/L.Methods: Two reviewers independently assessed eligibility, performed data extraction, and evaluated risk of bias of eligible articles. We adjusted the reported estimates for thromboprophylaxis and length of follow-up and used the median value from studies to determine cumulative incidence at 4 weeks postsurgery stratified by patient venous thromboembolism risk factors. The GRADE approach was applied to rate evidence certainty.Results: We included 188 studies (398,167 patients) reporting on 37 gynecologic cancer surgery procedures. The evidence certainty was generally low to very low. Median symptomatic venous thromboembolism risk (in the absence of prophylaxis) was <1% in 13 of 37 (35%) procedures, 1% to 2% in 11 of 37 (30%), and >2.0% in 13 of 37 (35%). The risks of venous thromboembolism varied from 0.1% in low venous thromboembolism risk patients undergoing cervical conization to 33.5% in high venous thromboembolism risk patients undergoing pelvic exenteration. Estimates of bleeding requiring reintervention varied from <0.1% to 1.3%. Median risks of bleeding requiring reintervention were <1% in 22 of 29 (76%) and 1% to 2% in 7 of 29 (24%) procedures.Conclusion: Venous thromboembolism reduction with thromboprophylaxis likely outweighs the increase in bleeding requiring reintervention in many gynecologic cancer procedures (eg, open surgery for ovarian cancer and pelvic exenteration). In some procedures (eg, laparoscopic total hysterectomy without lymphadenectomy), thromboembolism and bleeding risks are similar, and decisions depend on individual risk prediction and values and preferences regarding venous thromboembolism and bleeding

Harvest time and drying temperature effect on secondary metabolites in Rhodiola rosea

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Elaboration of growing methods of Bidens tripartita L. in Finland

vokMTT Mikkel

Biomass accumulation of Epilobium angustifolium in natural and cultivated populations

vokMTT Mikkel

Optimization of the fermentation of Bergenia sp. green leaves

Appendix 1. Recommendation for the fermentation process of Bergenia leaf yieldThe leaves of the commonly known decorative perennial, Bergenia species have several interesting biological activities. The green leaves contain arbutin up to 22 % (d.w.), a compound, which is used in cosmetic industry as a skin-whitening agent in humans. Tea prepared from the naturally fermented black leaves is used as beverage called Siberian tea or Mongolian tea in Russian ethno medicine. The fermented green leaves of Bergenia crassifolia are appearing to meet the criteria of being adaptogen. For the utilization of these new possibilities of Bergenia species during 2012–2014 several studies were carried out in SPECICROP project for elaborating a semi-industrial fermentation process of Bergenia leaf yield. The experiments were carried out in MTT Agrifood Research Finland Mikkeli with cooperation of St.-Petersburg Institute of Pharmacy, St-Petersburg, Russia. On the base of these experiments we elaborated the optimized parameters of the fermentation process and described a technological recommendation suitable for small size farm entrepreneurs.201