Differences and similarities between traditional day trading and cryptocurrency day trading

Stock trading has existed for over a century and cryptocurrency trading has existed for just over a decade. The cryptocurrency market has been growing at a tremendous pace, the market capitalisation was just short of $2.9 trillion at its highest point. Some traditional traders might be tempted to try cryptocurrency trading and multiply their profits because cryptocurrency has proven to provide unrealistic gains. The aim of this paper is to find out if traditional traders and cryptocurrency traders follow the same strategies or if they have their own set of strategies. During the writing of this dissertation, a simple comparison of survey answers was done to achieve the results. The paper attempts to highlight the key differences and similarities between the traders who trade only cryptocurrencies, and traders who trade only in traditional securities, by assessing the answers provided in the surveys and often utilising the answers provided by the traders who traded both as a benchmark. The periodicals of existing literature and internet articles were extensively used to complete this work such as the technical indicators utilised by the traders, their experience, the amount of profit they make, the aggressiveness of trading, their opinions on the future of trading and so on. The theoretical and practical significance of the work may be useful for future researchers in this study, traditional traders who want to opt cryptocurrency trading or vice-versa, trading enthusiasts and security exchange commissions.A negociação de ações existe há mais de um século e a negociação de criptomoedas existe há pouco mais de uma década. O mercado de criptomoedas vem crescendo em um ritmo tremendo, a capitalização de mercado ficou abaixo de US$ 2,9 trilhões em seu ponto mais alto. Alguns traders tradicionais podem ficar tentados a tentar negociar com criptomoedas e multiplicar seus lucros porque a criptomoeda provou fornecer ganhos irreais. O objetivo deste artigo é descobrir se os traders tradicionais e os traders de criptomoedas seguem as mesmas estratégias ou se possuem seu próprio conjunto de estratégias. Durante a redação desta dissertação, uma simples comparação das respostas da pesquisa foi feita para alcançar os resultados. O artigo tenta destacar as principais diferenças e semelhanças entre os traders que negociam apenas criptomoedas e traders que negociam apenas títulos tradicionais, avaliando as respostas fornecidas nas pesquisas e frequentemente utilizando as respostas fornecidas pelos traders que negociaram ambos como referência. Os periódicos da literatura existente e artigos da internet foram amplamente utilizados para completar este trabalho, como os indicadores técnicos utilizados pelos traders, sua experiência, a quantidade de lucro que obtêm, a agressividade da negociação, suas opiniões sobre o futuro da negociação e assim por diante. O significado teórico e prático do trabalho pode ser útil para futuros pesquisadores deste estudo, comerciantes tradicionais que desejam optar por criptomoeda ou vice-versa, entusiastas de negociação e comissões de câmbio de segurança

Modelos teóricos de discapacidad: un seguimiento del desarrollo histórico del concepto de discapacidad en las últimas cinco décadas

El concepto de discapacidad ha sido extensamente debatido en las últimas cinco décadas, dando fruto a múltiples definiciones y a la proliferación de modelos teóricos que tratan de explicar la discapacidad. Pero a pesar de tal abundancia de estudios, parece que seguimos siendo incapaces de explicar la discapacidad siguiendo un único modelo o definición. En este artículo ofrecemos un breve estudio diacrónico y comparativo de los principales modelos teóricos de la discapacidad, resaltando beneficios y aspectos a mejorar. El propósito último del artículo es subrayar la idea de que la discapacidad es un concepto amplio y en constante evolución

Comprehensive Evaluation of Anti-hyperglycemic Activity of Fractionated Momordica charantia

The present study evaluates anti-hyperglycemic activity of fractionated Momordica charantia (bitter gourd) seed extracts. Fasting blood glucose levels were evaluated before and after administration of different fractions of the seed extract. Among the three fractions tested, fraction Mc-3 (15 mg/kg b.wt.) showed the maximum anti-hyperglycemic activity and reduced blood glucose levels in experimental diabetic rats significantly. The activities of the key regulatory enzymes of glucose metabolism (hexokinase, pyruvate kinase, lactate dehydrogenase, and glucose-6-phosphate dehydrogenase) were determined in Mc-3-treated diabetic animals. Once-daily administration of the fraction Mc-3 for prolonged period of 18 days to the experimental diabetic animals did not result in any nephrotoxicity or hepatotoxicity as evident from insignificant changes in biochemical parameters indicative of liver and kidney functions. Further fractionation of the fraction Mc-3 by size exclusion chromatography resulted in a fraction, designated Mc-3.2, possessing anti-hyperglycemic activity. The fraction Mc-3.2 showed the presence of a predominant protein band of ~11 kDa on SDS-PAGE. Loss in anti-hyperglycemic activity of the Mc-3.2 upon protease treatment indicates the proteinaceous nature of the anti-hyperglycemic principles. Overall, the results suggest that Momordica charantia seeds contain an effective anti-hyperglycemic protein(s) which may find application in treatment of diabetes without evident toxic effects

Immune escape and metastasis mechanisms in melanoma: breaking down the dichotomy

Melanoma is one of the most lethal neoplasms of the skin. Despite the revolutionary introduction of immune checkpoint inhibitors, metastatic spread, and recurrence remain critical problems in resistant cases. Melanoma employs a multitude of mechanisms to subvert the immune system and successfully metastasize to distant organs. Concerningly, recent research also shows that tumor cells can disseminate early during melanoma progression and enter dormant states, eventually leading to metastases at a future time. Immune escape and metastasis have previously been viewed as separate phenomena; however, accumulating evidence is breaking down this dichotomy. Recent research into the progressive mechanisms of melanoma provides evidence that dedifferentiation similar to classical epithelial to mesenchymal transition (EMT), genes involved in neural crest stem cell maintenance, and hypoxia/acidosis, are important factors simultaneously involved in immune escape and metastasis. The likeness between EMT and early dissemination, and differences, also become apparent in these contexts. Detailed knowledge of the mechanisms behind “dual drivers” simultaneously promoting metastatically inclined and immunosuppressive environments can yield novel strategies effective in disabling multiple facets of melanoma progression. Furthermore, understanding progression through these drivers may provide insight towards novel treatments capable of preventing recurrence arising from dormant dissemination or improving immunotherapy outcomes

Two factors, one direction towards social regulation policy convergence: Learning from policy experts in Norway and India

Two significantly different countries such as Norway and India have adopted similar social regulation policies aimed at the employment of disabled people since the 1990s. Countries can adopt social regulation policies, such as anti-discrimination provisions, owing to multiple factors. This article uncovers two common factors leading to policy convergence within social regulation reforms aimed at the employment of disabled people in Norway and India. An exploratory qualitative case study was conducted, wherein 25 policy experts (11 from Norway and 14 from India) were interviewed. Findings from expert interviews indicate that the observed policy convergence are connected to two trends that can be detected both in Norway and India. The first concerns the influence of international treaties; the second concerns grassroots mobilization of disabled people and their organizations. Findings point towards increasing internationalization of social regulation policies and these policy developments transcend the global North and global South divide

Insider, Outsider or an In-Betweener? Epistemological Reflections of a Legally Blind Researcher on Conducting Cross-National Disability Research

Researchers have long debated the perils and possibilities associated with being an insider or an outsider while conducting qualitative research. This paper revisits this insider-outsider debate by drawing on the experiential insights of a legally blind researcher who, as a part of a comparative study, conducted qualitative interviews with 29 young adults with visual impairments from Oslo and Delhi in 2017 and 2018. It inquires into how the researcher’s positionality and identity influences the process of knowledge production while conducting Global North-South comparative disability research. Based on critical reflections across different stages of the research process, the paper problematizes the simplistic binaries, such as insider-outsider, Privileged-Oppressed, Us-Them and Native-Foreign. It argues for the adoption of an in-betweener researcher status located somewhere on the insider-outsider continua. Comparative disability research entailing Global North and Global South countries is scarce. This paper offers valuable epistemological insights for other researchers working with marginalized groups