Understanding the Heavy Fermion Phenomenology from Microscopic Model

We solve the 3D periodic Anderson model via two impurity DMFT. We obtain the temperature v.s. hybridization phase diagram. In approaching the quantum critical point (QCP) both the Neel and lattice Kondo temperatures decrease and they do not cross at the lowest temperature we reached. While strong ferromagnetic spin fluctuation on the Kondo side is observed, our result indicates the critical static spin susceptibility is local in space at the QCP. We observe in the crossover region logarithmic temperature dependence in the specific heat coefficient and spin susceptibility

Create your own degree: Empowering students to find belonging in science

The Integrated Sciences specialization was introduced in recognition that the university was losing very talented science students who were frustrated by the constraints involved in following a traditional degree program. As such, it is an alternative to a traditional major or honours science program, and gives students the opportunity to design their own curriculum with the mentorship of a faculty member specializing in the chosen field of interest. Because the process of developing a degree program takes time, commitment, and effort, the students are highly motivated and engaged with their curriculum. As a result of the interdisciplinary nature of the program they graduate with a wide breadth of scientific knowledge. Almost all Integrated Sciences graduates go on to professional or graduate schools. The specialization admits approximately 110 students per year, most at the end of their first year. Because of the small size the students develop a strong sense of belonging. This is reinforced by core ISCI courses, a peer mentoring program and a strong student club. The main barrier to introducing a similar specialization at other universities appears to be the need for senate approval of new degree programs. We are fortunate that the founders of the specialization at the University of British Columbia (UBC) negotiated blanket approval for our student\u27s individual programs. This interactive presentation will provide an overview of the Integrated Sciences specialization, discussion on supporting and empowering students throughout their degree, and modes of collaboration and mentorship amongst students, staff, and faculty to create a sense of belonging in science

Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns.

Autologous skin grafting from the thigh is frequently required for treatment of burns and is associated with intense pain at the donor site. Local anesthetic-based (LA) nerve blocks of the lateral femoral cutaneous nerve (LFCN) have been demonstrated to provide analgesia when the graft is taken from the lateral thigh. However, the duration of these single injection blocks has been reported to average only 9 hours, whereas the pain from the procedure lasts days or weeks. Continuous LA nerve blocks can also be used to provide analgesia during serial debridement of burns, although this requires placement of a perineural catheter which may increase infection risk in a population with an increased susceptibility to infection. Cryoneurolysis of the LFCN can potentially provide analgesia of the lateral thigh for skin graft harvesting or serial burn debridement that lasts far longer than conventional LA nerve blocks. Here, we present a series of three patients who received a combination of a LA nerve block and cryoneurolysis nerve block of the LFCN for analgesia of the lateral thigh. Two of these patients had the blocks placed before harvesting a split thickness skin graft. The third received the blocks for outpatient wound care of a burn to the lateral thigh. In all cases, the resulting analgesia lasted more than 1 week. A single cryoneurolysis block of the LFCN successfully provided extended duration analgesia of the lateral thigh for autologous skin graft donor site or wound care of a burn in three patients

Early TBI-Induced Cytokine Alterations are Similarly Detected by Two Distinct Methods of Multiplex Assay

Annually, more than a million persons experience traumatic brain injury (TBI) in the US and a substantial proportion of this population develop debilitating neurological disorders, such as, paralysis, cognitive deficits, and epilepsy. Despite the long-standing knowledge of the risks associated with TBI, no effective biomarkers or interventions exist. Recent evidence suggests a role for inflammatory modulators in TBI-induced neurological impairments. Current technological advances allow for the simultaneous analysis of the precise spatial and temporal expression patterns of numerous proteins in single samples which ultimately can lead to the development of novel treatments. Thus, the present study examined 23 different cytokines, including chemokines, in the ipsi and contralateral cerebral cortex of rats at 24 h after a fluid percussion injury (FPI). Furthermore, the estimation of cytokines were performed in a newly developed multiplex assay instrument, MAGPIX (Luminex Corp), and compared with an established instrument, Bio-Plex (Bio-Rad), in order to validate the newly developed instrument. The results show numerous inflammatory changes in the ipsi and contralateral side after FPI that were consistently reported by both technologies

Lorentz invariance of entanglement classes in multipartite systems

We analyze multipartite entanglement in systems of spin-1/2 particles from a relativistic perspective. General conditions which have to be met for any classification of multipartite entanglement to be Lorentz invariant are derived, which contributes to a physical understanding of entanglement classification. We show that quantum information in a relativistic setting requires the partition of the Hilbert space into particles to be taken seriously. Furthermore, we study exemplary cases and show how the spin and momentum entanglement transforms relativistically in a multipartite setting.Comment: v2: 5 pages, 4 figures, minor changes to main body, journal references update

Pennsylvania Folklife Vol. 21, No. 2

• The Pennsylvania Germans: A Preliminary Reading List • Spatial Development of the Southeastern Pennsylvania Plain Dutch Community to 1970: Part I • Palatine Emigrants of the 18th Century • Winter Album • Emigrants from Dossenheim (Baden) in the 18th Century • Farm Layouts and Building Plans: Folk-Cultural Questionnaire No. 22https://digitalcommons.ursinus.edu/pafolklifemag/1046/thumbnail.jp

Canonical forms for complex matrix congruence and *congruence

Canonical forms for congruence and *congruence of square complex matrices were given by Horn and Sergeichuk in [Linear Algebra Appl. 389 (2004) 347-353], based on Sergeichuk's paper [Math. USSR, Izvestiya 31 (3) (1988) 481-501], which employed the theory of representations of quivers with involution. We use standard methods of matrix analysis to prove directly that these forms are canonical. Our proof provides explicit algorithms to compute all the blocks and parameters in the canonical forms. We use these forms to derive canonical pairs for simultaneous congruence of pairs of complex symmetric and skew-symmetric matrices as well as canonical forms for simultaneous *congruence of pairs of complex Hermitian matrices.Comment: 31 page

Canonical matrices of bilinear and sesquilinear forms

Canonical matrices are given for (a) bilinear forms over an algebraically closed or real closed field; (b) sesquilinear forms over an algebraically closed field and over real quaternions with any nonidentity involution; and (c) sesquilinear forms over a field F of characteristic different from 2 with involution (possibly, the identity) up to classification of Hermitian forms over finite extensions of F. A method for reducing the problem of classifying systems of forms and linear mappings to the problem of classifying systems of linear mappings is used to construct the canonical matrices. This method has its origins in representation theory and was devised in [V.V. Sergeichuk, Math. USSR-Izv. 31 (1988) 481-501].Comment: 44 pages; misprints corrected; accepted for publication in Linear Algebra and its Applications (2007

Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1

We describe the use of iterative in situ click chemistry to design an Akt-specific branched peptide triligand that is a drop-in replacement for monoclonal antibodies in multiple biochemical assays. Each peptide module in the branched structure makes unique contributions to affinity and/or specificity resulting in a 200 nM affinity ligand that efficiently immunoprecipitates Akt from cancer cell lysates and labels Akt in fixed cells. Our use of a small molecule to preinhibit Akt prior to screening resulted in low micromolar inhibitory potency and an allosteric mode of inhibition, which is evidenced through a series of competitive enzyme kinetic assays. To demonstrate the efficiency and selectivity of the protein-templated in situ click reaction, we developed a novel QPCR-based methodology that enabled a quantitative assessment of its yield. These results point to the potential for iterative in situ click chemistry to generate potent, synthetically accessible antibody replacements with novel inhibitory properties