11,861 research outputs found
Pulse ignition characterization of mercury ion thruster hollow cathode using an improved pulse ignitor
An investigation of the high voltage pulse ignition characteristics of the 8 cm mercury ion thruster neutralizer cathode identified a low rate of voltage rise and long pulse duration as desirable factors for reliable cathode starting. Cathode starting breakdown voltages were measured over a range of mercury flow rates and tip heater powers for pulses with five different rates of voltage rise. Breakdown voltage requirements for the fastest rising pulse (2.5 to 3.0 kV/micro sec) were substantially higher (2 kV or more) than for the slowest rising pulse (0.3 to 0.5 kV/micro sec) for the same starting conditions. Also described is an improved, low impedance pulse ignitor circuit which reduces power losses and eliminates problems with control and packaging associated with earlier designs
Microarray gene expression profiling of neural tissues in bovine spastic paresis
Abstract: Background: Bovine Spastic Paresis (BSP) is a neuromuscular disorder which affects both male and female cattle. BSP is characterized by spastic contraction and overextension of the gastrocnemious muscle of one or both limbs and is associated with a scarce increase in body weight. This disease seems to be caused by an autosomal and recessive gene, with incomplete penetration, although no genes clearly involved with its onset have been so far identified. We employed cDNA microarrays to identify metabolic pathways affected by BSP in Romagnola cattle breed. Investigation of those pathways at the genome level can help to understand this disease.
Results: Microarray analysis of control and affected individuals resulted in 268 differentially expressed genes. These genes were subjected to KEGG pathway functional clustering analysis, revealing that they are predominantly involved in Cell Communication, Signalling Molecules and Interaction and Signal Transduction, Diseases and Nervous System classes. Significantly enriched KEGG pathway's classes for the differentially expressed genes were calculated; interestingly, all those significantly under-expressed in the affected samples are included in Neurodegenerative Diseases. To identify genome locations possibly harbouring gene(s) involved in the disease, the chromosome distribution of the differentially expressed genes was also investigated.
Conclusions: The cDNA microarray we used in this study contains a brain library and, even if carrying an incomplete transcriptome representation, it has proven to be a valuable tool allowing us to add useful and new information to a poorly studied disease. By using this tool, we examined nearly 15000 transcripts and analysed gene pathways affected by the disease. Particularly, our data suggest also a defective glycinergic synaptic transmission in the development of the disease and an alteration of calcium signalling proteins. We provide data to acquire knowledge of a genetic disease for which literature still presents poor results and that could be further and specifically analysed in the next future. Moreover this study, performed in livestock, may also harbour molecular information useful for understanding human diseases
Defect Identification and Sizing by the Ultrasonic Satellite-Pulse Technique
Type and size are the most important defect characteristics that need to be determined for reliable prediction of the remaining service lifetime of a defective structure or part. The analytical and supporting experimental results presented in this paper concern a universal ultrasonic defect-identificationand- subsequent-sizing method. The conceived satellite-pulse technique (SPT) is based on the interpretation, in terms of defect types and dimensions, of the separation in time-of-arrival between the specularly-reflected pulse and its tip-diffracted or tangentially-scattered satellite contained in the composite defect signal. Several alternate calibration procedures were also developed, any one of which enables the ultrasonic examiner to make the time scale of the oscilloscope read directly in terms of equivalent crack depth or void diameter as appropriate
Macroscopic equations for the adiabatic piston
A simplified version of a classical problem in thermodynamics -- the
adiabatic piston -- is discussed in the framework of kinetic theory. We
consider the limit of gases whose relaxation time is extremely fast so that the
gases contained on the left and right chambers of the piston are always in
equilibrium (that is the molecules are uniformly distributed and their
velocities obey the Maxwell-Boltzmann distribution) after any collision with
the piston. Then by using kinetic theory we derive the collision statistics
from which we obtain a set of ordinary differential equations for the evolution
of the macroscopic observables (namely the piston average velocity and
position, the velocity variance and the temperatures of the two compartments).
The dynamics of these equations is compared with simulations of an ideal gas
and a microscopic model of gas settled to verify the assumptions used in the
derivation. We show that the equations predict an evolution for the macroscopic
variables which catches the basic features of the problem. The results here
presented recover those derived, using a different approach, by Gruber, Pache
and Lesne in J. Stat. Phys. 108, 669 (2002) and 112, 1177 (2003).Comment: 13 pages, 7 figures (revTeX4) The paper has been completely rewritten
with new derivation and results, supplementary information can be found at
http://denali.phys.uniroma1.it/~cencini/Papers/cppv07_supplements.pd
Removal, Remand, and Review in Pendent Claim and Pendent Party Cases
This Article examines the removability of civil actions that include either pendent claims or pendent parties joined in addition to parties against whom federal questions are alleged. It discusses the remandability of those civil actions or segments of them, and comments on the law governing appellate review of district court remands to state court.\u27 In an effort to reach the wisest resolutions of the various issues posed, it confronts issues of statutory construction, interprets Supreme Court cases, especially Thermtron Products, Inc. v. Hermansdorfer,\u27and wades in the murky waters of federalism. In the course of this enterprise, the Article analyzes and strongly takes issue with the recent decision of the Supreme Court in Carnegie-Mellon University v. Cohill. The implications of Carnegie-Mellon also are explored.
The Article focuses on the problems that have arisen and can arise in federal question cases removable, if at all, under 28 U.S.C. sections 1441(a) and (b).\u27 It is noteworthy that these issues arise frequently, as evidenced by the number of pertinent decisions, and promise to continue to plague the federal courts in view of the substantial number of cases removed to federal court. The issues of removal jurisdiction, remandability, and reviewability tackled here are questions of federal court jurisdiction, powers, and discretion, that broadly implicate our federalism
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