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    An ethnobotanical study of plants used for the treatment of diabetes in the Eastern Cape Province, South Africa

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    Diabetes mellitus is one of the commonest diseases affecting the citizens of both developed and poor countries. In South Africa, the number of people suffering from diabetes is believed to be rising steadily. An ethnobotanical study of plants used by the traditional healers, herbalists and rural dwellersfor the treatment of diabetes mellitus was conducted in the Eastern Cape Province. The study revealed 14 plant species belonging to six families namely; Asteraceae, Hypoxidaceae, Apocynaceae, Asphodelaceae, Apiaceae and Buddlejaceae. The use of infusions from plant leaves and roots was thecommonest method of herbal preparation. In all cases, the treatment involved drinking the extracts for a long period of time. There was a general belief on the efficacy of the prepared extracts

    Off-Label Use of Phosphodiesterase Type 5 Inhibitor Erectile Dysfunction Medication to Enhance Sex Among Gay and Bisexual Men in Australia: Results from the FLUX Study

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    Introduction: Gay and bisexual men (GBM) use erectile dysfunction medications (EDM) such as Viagraℱ, Cialisℱ and Levitraℱ often with little evidence of medical indication that might necessitate their use. Aim: We investigate the prevalence and contexts of, and motivations for, EDM use, and its relationship to sexual risk behavior. Method: Between September 2014 and July 2015, Australian GBM were invited to enroll online through social networking and gay community sites to complete a comprehensive survey looking at licit and illicit drug use and their associated behaviors. A total of 2250 GBM completed the questionnaire. Main outcome measures: Any EDM use, and at least weekly use in the previous six months. Results: Two thirds (67.7%) reported no history of EDM use in their lifetime. Approximately one in ten participants (11.1%) had last used EDM more than six months ago. In the previous six months, 11.5% reported using EDM less than monthly, 5.3% at least monthly, and 4.5% weekly or more often. Among men who had used EDM in the previous six months, the most common reasons cited for its use were: to maintain an erection for longer (73.3%), to make it easier to get hard (67.3%), and difficulty in attaining or maintain an erection (53.5%). Conclusion: While some GBM use EDM specifically for erectile dysfunction, many also use EDM to enhance their sexual experiences. Often, this occurs in the context of intensive sex partying, which may include risky sexual behavior. The use of EDM in the context of intensive sex partying (which include the combined use of EDM and illicit drugs), with the associated potential for increased risk of HIV transmission, indicates a need to consider the use of EDM among GBM in HIV prevention

    Origin of Ultralow Friction andWear in Ultrananocrystalline Diamond

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    The impressively low friction and wear of diamond in humid environments is debated to originate from either the stability of the passivated diamond surface or sliding-induced graphitization/rehybridization of carbon. We find ultralow friction and wear for ultrananocrystalline diamond surfaces even in dry environments, and observe negligible rehybridization except for a modest, submonolayer amount under the most severe conditions (high load, low humidity). This supports the passivation hypothesis, and establishes a new regime of exceptionally low friction and wear for diamond

    Thermal Stability and Rehybridization of Carbon Bonding in Tetrahedral Amorphous Carbon

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    We preform a quantitative investigation of the energetics of thermally induced sp3 → sp2 conversion of carbon-carbon bonds in tetrahedral amorphous carbon (ta-C) films by using near edge x-ray absorption fine structure (NEXAFS) and Raman spectroscopy. We investigate the evolution of the bonding configuration in ta-C thin films subjected to high temperature annealing in flowing Argon gas using a rapid thermal annealing furnace over the range of 200-1000 ÂșC. We observe no substantial change in bonding structure below 600 ÂșC, and by 1000 ÂșC a significant increase in the sp2 bonding in the film is observed. No oxygen bonding is detected in the NEXAFS spectra, but we do observe an isosbestic point, demonstrating that the thermally driven sp3 → sp2 conversion reaction occurs without passing through an intermediate transition state. This allows us to use NEAFS spectra of thermally annealed ta-C films to quantitatively determine that the activation energy for directly converting the sp3-bonded carbon to the s
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