Design and fabrication of a mid infra-red photonic crystal defect laser in indium antimonide

This paper presents 2D FDTD modelling and prototype fabrication of a mid-infrared photonic crystal defect laser. The device is fabricated using a two stage Focused Ion Beam process which results in improved hole profiles

Novel Optical Remote Sensing And Ground-Truthing Of Benthic Habitat Using The Burrow-Cutter-Diaz Plowing Sediment Profile Camera System (Bcd Sled)

The Jefferson Benthic Sled provides video sediment profile imagery of continuous cross-sectional data. Subsurface imaging is achieved by attaching a profile camera prism behind an agricultural plow that extends beneath the plane of the sled skids, slicing through the top 10 to 20 cm of sediment. The plowing video profile provides a high-resolution, real-time: remotely controlled view of the flat side of the plow furrow. Successful continuous profiles of up to 100 m have been collected. The equipment allows immediate characterization of benthic habitats, transition zones, sediment types, sediment oxidation layering, biological resources, and fisheries impact

A multiple case study of an interorganizational collaboration: Exploring the first year of an industry partnership focused on middle school engineering education

Background: Calls to improve learning in science, technology, engineering, and mathematics (STEM), and particularly engineering, present significant challenges for school systems. Partnerships among engineering industry, universities, and school systems to support learning appear promising, but current work is limited in its conclusions because it lacks a strong connection to theoretical work in interorganizational collaboration. Purpose/Hypothesis: This study aims to reflect more critically on the process of how organizations build relationships to address the following research question: In a public–private partnership to integrate engineering into middle school science curriculum, how do stakeholder characterizations of the collaborative process align with existing frameworks of interorganizational collaboration?. Design/Method: This qualitative, embedded multiple case study considered in-depth pre- and post-year interviews with teachers, administrators, industry, and university personnel during the first year of the Partnering with Educators and Engineers in Rural Schools (PEERS) program. Transcripts were analyzed using a framework of interorganizational collaboration operationalized for our context. Results: Results provide insights into stakeholder perceptions of collaborative processes in the first year of the PEERS program across dimensions of collaboration. These dimensions mapped to three central discussion points with relevance for school–university–industry partnerships: school collaboration as an emergent and negotiated process, tension in collaborating across organizations, and fair share in collaborating toward a social goal. Conclusions: Taking a macro-level look at the collaborative processes involved enabled us to develop implications for collaborative stakeholders to be intentional about designing for future success. By systematically applying a framework of collaboration and capitalizing on the rich situational findings possible through a qualitative approach, we shift our understanding of collaborative processes in school–university–industry partnerships for engineering education and contribute to the development of collaboration theory

Two patients with cystic fibrosis, nonsense mutations in each cystic fibrosis gene, and mild pulmonary disease

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Prevalence of dog erythrocyte antigen (DEA) 1 amongst the dog blood donors at Tamil Nadu veterinary and animal sciences university animal blood bank (TABB), India

The study of dog blood groups has increased in the last years. Inherited antigens on the RBC surface define blood groups. There are 7 blood groups in the canine DEA system. Amongst these blood groups, DEA 1 blood group is highly immunogenic and consequently has greater clinical importance. A retrospective study was conducted in 125 purebred and mongrel dog blood donors at the TANUVAS Animal Blood Bank, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India during the period from January 2010 to January 2011. Donor dogs were screened and typed for the presence of DEA 1 using the monoclonal antibody kit. The prevalence of DEA 1 was 61.6%. The prevalence of DEA 1 dogs in India agrees with most of the data reported in the literature

Building Community Capacity for Integrating Engineering in Rural Middle School Science Classrooms

: Broadening participation in engineering is an important national priority and has led to increasing demands for engineering content to be integrated into traditional K-12 curriculum. However, expecting teachers to incorporate engineering into their classrooms without additional training or resources is unreasonable. Partnering teachers with industry partners is one promising way to prioritize integrated science and engineering content while also introducing youth to possible career paths. In this programmatic article, we introduce the Partnering with Educators and Engineers in Rural Schools (PEERS) project that focuses on the collaborative design, implementation, and study of recurrent hands-on engineering activities with middle school youth in three rural communities in or near Appalachia. We discuss the curricular priorities of the program as well as preliminary findings on both student-focused and capacity-building metrics across the partnerships. Key discussion points include (1) a need to distill goals for engineering outreach by wrestling with what success might really look like for middle-school youth engagement with engineering and (2) cultivating community capacity to better support education systems and the simultaneous potential for and challenges of collaborating to build such infrastructure

Peak-Clustering Method for MEG Group Analysis to Minimise Artefacts Due to Smoothness

Magnetoencephalography (MEG), a non-invasive technique for characterizing brain electrical activity, is gaining popularity as a tool for assessing group-level differences between experimental conditions. One method for assessing task-condition effects involves beamforming, where a weighted sum of field measurements is used to tune activity on a voxel-by-voxel basis. However, this method has been shown to produce inhomogeneous smoothness differences as a function of signal-to-noise across a volumetric image, which can then produce false positives at the group level. Here we describe a novel method for group-level analysis with MEG beamformer images that utilizes the peak locations within each participant’s volumetric image to assess group-level effects. We compared our peak-clustering algorithm with SnPM using simulated data. We found that our method was immune to artefactual group effects that can arise as a result of inhomogeneous smoothness differences across a volumetric image. We also used our peak-clustering algorithm on experimental data and found that regions were identified that corresponded with task-related regions identified in the literature. These findings suggest that our technique is a robust method for group-level analysis with MEG beamformer images

Creation of Laryngeal Grafts from Primary Human Cells and Decellularized Laryngeal Scaffolds

Current reconstruction methods of the laryngotracheal segment fail to replace the complex functions of the human larynx. Bioengineering approaches to reconstruction have been limited by the complex tissue compartmentation of the larynx. We attempted to overcome this limitation by bio-engineering laryngeal grafts from decellularized canine laryngeal scaffolds recellularized with human primary cells under one uniform culture medium condition. First, we generated laryngeal scaffolds with preserved glycosaminoglycan content and biomechanical properties by detergent perfusion-decellularization over nine days. We proofed biocompatibility by absence of a CD3 lymphocyte response to subcutaneously implanted scaffolds in immune-competent rats. We then developed a uniform culture medium that strengthened the endothelial barrier over 5 days after an initial growth phase. Simultaneously, this culture medium supported airway epithelial cell and skeletal myoblast growth while maintaining their full differentiation and maturation potential. We then applied the uniform culture medium composition to whole laryngeal scaffolds seeded with endothelial cells from both carotid arteries and external jugular veins and generated re-endothelialized arterial and venous vascular beds. Under the same culture medium condition, we bio-engineered epithelial monolayers onto laryngeal mucosa and repopulated intrinsic laryngeal muscle. We were then able to demonstrate early muscle formation in heterotopic transplantations in immuno-deficient mice. The model supported the formation of three humanized laryngeal tissue compartments under one uniform culture condition, possibly a key factor in developing, complex, multicellular, ready-to-transplant tissue grafts