27 research outputs found

    basic concepts on systems of systems

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    A System of System (SoS) stems from the integration of existing systems (legacy systems), normally operated by different organizations, and new systems that have been designed to take advantage of this integration

    Motivations of women who organized others for prostitution: Evidence from a female prison in China

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    This article discusses women’s involvement in sex work management – an offence defined under section 358 of the 1997 Chinese Criminal Law and one of the re-emerged areas of illegality following the economic reforms since 1978. It first provides the historical context, legislative background and relevant sections of the Chinese vice laws so as to help make sense of the data obtained. Then it discusses the methodological issues before presenting the empirical findings to explore the socio-demographic profile of the incarcerated female sex work organizers who participated in this study and their motivations for organizing others for prostitution. Based on empirical data, this article explores the impact of social conditions on female offenders in China’s reform era and also the effects of the anti-prostitution policy in the country. Moreover, through a Chinese case study, it makes contributions to broader scholarship on the sex trade regulation. It concludes with a couple of implications for policy and practice

    Overexpression of the erbB-2

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    Evaluation of outcome and prognostic factors for dogs living greater than one year after diagnosis of osteosarcoma: 90 cases (1997–2008)

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    OBJECTIVE: To evaluate clinical characteristics, outcome, and prognostic variables in a cohort of dogs surviving > 1 year after an initial diagnosis of osteosarcoma. DESIGN: Retrospective case series. ANIMALS: 90 client-owned dogs. PROCEDURES: Medical records for an 11-year period from 1997 through 2008 were reviewed, and patients with appendicular osteosarcoma that lived > 1 year after initial histopathologic diagnosis were studied. Variables including signalment, weight, serum alkaline phosphatase activity, tumor location, surgery, and adjuvant therapies were recorded. Median survival times were calculated by means of a Kaplan-Meier survival function. Univariate analysis was conducted to compare the survival function for categorical variables, and the Cox proportional hazard model was used to evaluate the likelihood of death > 1 year after diagnosis on the basis of the selected risk factors. RESULTS: 90 dogs met the inclusion criteria; clinical laboratory information was not available in all cases. Median age was 8.2 years (range, 2.7 to 13.3 years), and median weight was 38 kg (83.6 lb; range, 21 to 80 kg [46.2 to 176 lb]). Serum alkaline phosphatase activity was high in 29 of 60 (48%) dogs. The most common tumor location was the distal portion of the radius (54/90 [60%]). Eighty-nine of 90 (99%) dogs underwent surgery, and 78 (87%) received chemotherapy. Overall, 49 of 90 (54%) dogs developed metastatic disease. The median survival time beyond 1 year was 243 days (range, 1 to 1,899 days). Dogs that developed a surgical-site infection after limb-sparing surgery had a significantly improved prognosis > 1 year after osteosarcoma diagnosis, compared with dogs that did not develop infections. CONCLUSIONS AND CLINICAL RELEVANCE: Results of the present study indicated that dogs with an initial diagnosis of osteosarcoma that lived > 1 year had a median survival time beyond the initial year of approximately 8 months. As reported previously, the development of a surgical-site infection in dogs undergoing a limb-sparing surgery significantly affected prognosis and warrants further study
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