Citizens’ use of policy symbols and frames

Public policy, Interpretive methods, Education policy, Desegregation, Policy narratives, Policy symbols,

Broken R-Parity in the Sky and at the LHC

Supersymmetric extensions of the Standard Model with small R-parity and lepton number violating couplings are naturally consistent with primordial nucleosynthesis, thermal leptogenesis and gravitino dark matter. We consider supergravity models with universal boundary conditions at the grand unification scale, and scalar tau-lepton or bino-like neutralino as next-to-lightest superparticle (NLSP). Recent Fermi-LAT data on the isotropic diffuse gamma-ray flux yield a lower bound on the gravitino lifetime. Comparing two-body gravitino and neutralino decays we find a lower bound on a neutralino NLSP decay length, c \tau_{\chi^0_1} \gsim 30 cm. Together with gravitino and neutralino masses one obtains a microscopic determination of the Planck mass. For a stau-NLSP there exists no model-independent lower bound on the decay length. Here the strongest bound comes from the requirement that the cosmological baryon asymmetry is not washed out, which yields c \tau_{\tilde\tau_1} \gsim 4 mm. However, without fine-tuning of parameters, one finds much larger decay lengths. For typical masses, $m_{3/2} \sim 100 GeV$ and $m_{NLSP} \sim 150 GeV$, the discovery of a photon line with an intensity close to the Fermi-LAT limit would imply a decay length $c\tau_{NLSP}$ of several hundred meters, which can be measured at the LHC.Comment: 30 pages, 8 figures; v2: published version, reference adde

Data from: Life in the fat lane: seasonal regulation of insulin sensitivity, food intake, and adipose biology in brown bears

Grizzly bears (Ursus arctos horribilis) have evolved remarkable metabolic adaptations including enormous fat accumulation during the active season followed by fasting during hibernation. However, these fluctuations in body mass do not cause the same harmful effects associated with obesity in humans. To better understand these seasonal transitions, we performed insulin and glucose tolerance tests in captive grizzly bears, characterized the annual profiles of circulating adipokines, and tested the anorectic effects of centrally administered leptin at different times of the year. We also used bear gluteal adipocyte cultures to test insulin and beta-adrenergic sensitivity in vitro. Bears were insulin resistant during hibernation but were sensitive during the spring and fall active periods. Hibernating bears remained euglycemic, possibly due to hyperinsulinemia and hyperglucagonemia. Adipokine concentrations were relatively low throughout the active season but peaked in mid-October prior to hibernation when fat content was greatest. Serum glycerol was highest during hibernation, indicating ongoing lipolysis. Centrally administered leptin reduced food intake in October, but not in August, revealing seasonal variation in the brain’s sensitivity to its anorectic effects. This was supported by strong phosphorylated signal transducer and activator of transcription 3 labeling within the hypothalamus of hibernating bears; labeling virtually disappeared in active bears. Adipocytes collected during hibernation were insulin resistant when cultured with hibernation serum but became sensitive when cultured with active season serum. Heat treatment of active serum blocked much of this action. Clarifying the cellular mechanisms responsible for the physiology of hibernating bears may inform new treatments for metabolic disorders