5,052 research outputs found

    Observation of Amounts of Movement Practice Provided during Stroke Rehabilitation

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    Objective To investigate how much movement practice occurred during stroke rehabilitation, and what factors might influence doses of practice provided. Design Observational survey of stroke therapy sessions. Setting Seven inpatient and outpatient rehabilitation sites. Participants We observed a convenience sample of 312 physical and occupational therapy sessions for people with stroke. Interventions Not applicable. Main Outcome Measures We recorded numbers of repetitions in specific movement categories and data on potential modifying factors (patient age, side affected, time since stroke, FIM item scores, years of therapist experience). Descriptive statistics were used to characterize amounts of practice. Correlation and regression analyses were used to determine whether potential factors were related to the amount of practice in the 2 important categories of upper extremity functional movements and gait steps. Results Practice of task-specific, functional upper extremity movements occurred in 51% of the sessions that addressed upper limb rehabilitation, and the average number of repetitions/session was 32 (95% confidence interval [CI]=20–44). Practice of gait occurred in 84% of sessions that addressed lower limb rehabilitation and the average number of gait steps/session was 357 (95% CI=296–418). None of the potential factors listed accounted for significant variance in the amount of practice in either of these 2 categories. Conclusions The amount of practice provided during poststroke rehabilitation is small compared with animal models. It is possible that current doses of task-specific practice during rehabilitation are not adequate to drive the neural reorganization needed to promote function poststroke optimally

    Synthesis of the elements in stars: forty years of progress

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    Forty years ago Burbidge, Burbidge, Fowler, and Hoyle combined what we would now call fragmentary evidence from nuclear physics, stellar evolution and the abundances of elements and isotopes in the solar system as well as a few stars into a synthesis of remarkable ingenuity. Their review provided a foundation for forty years of research in all of the aspects of low energy nuclear experiments and theory, stellar modeling over a wide range of mass and composition, and abundance studies of many hundreds of stars, many of which have shown distinct evidence of the processes suggested by B2FH. In this review we summarize progress in each of these fields with emphasis on the most recent developments

    Continuum breakdown in hypersonic viscous flows

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76654/1/AIAA-2002-651-530.pd

    Biogeochemical and microbial seasonal dynamics between water column and sediment processes in a productive mountain lake: Georgetown Lake, MT, USA

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    This manuscript details investigations of a productive, mountain freshwater lake and examines the dynamic relationship between the chemical and stable isotopes and microbial composition of lake bed sediments with the geochemistry of the lake water column. A multidisciplinary approach was used in order to better understand the lake water- sediment interactions including quantification and sequencing of microbial 16S rRNA genes in a sediment core as well as stable isotope analysis of C, S, and N. One visit included the use of a pore water sampler to gain insight into the composition of dissolved solutes within the sediment matrix. Sediment cores showed a general decrease in total C with depth which included a decrease in the fraction of organic C combined with an increase in the fraction of inorganic C. One sediment core showed a maximum concentration of dissolved organic C, dissolved inorganic C, and dissolved methane in pore water at 4 cm depth which corresponded with a sharp increase in the abundance of 16S rRNA templates as a proxy for the microbial population size as well as the peak abundance of a sequence affiliated with a putative methanotroph. The isotopic separation between dissolved inorganic and dissolved organic carbon is consistent with largely aerobic microbial processes dominating the upper water column, while anaerobic microbial activity dominates the sediment bed. Using sediment core carbon concentrations, predictions were made regarding the breakdown and return of stored carbon per year from this temperate climate lake with as much as 1.3 Gg C yr(-1) being released in the form of CO2 and CH4

    Measuring Atmospheric Neutrino Oscillations with Neutrino Telescopes

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    Neutrino telescopes with large detection volumes can demonstrate that the current indications of neutrino oscillation are correct or if a better description can be achieved with non-standard alternatives. Observations of contained muons produced by atmospheric neutrinos can better constrain the allowed region for oscillations or determine the relevant parameters of non-standard models. We analyze the possibility of neutrino telescopes measuring atmospheric neutrino oscillations. We suggest adjustments to improve this potential. An addition of four densely-instrumented strings to the AMANDA II detector makes observations feasible. Such a configuration is competitive with current and proposed experiments.Comment: 36 pages, 21 figures, revte

    New generalized fuzzy metrics and fixed point theorem in fuzzy metric space

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    In this paper, in fuzzy metric spaces (in the sense of Kramosil and Michalek (Kibernetika 11:336-344, 1957)) we introduce the concept of a generalized fuzzy metric which is the extension of a fuzzy metric. First, inspired by the ideas of Grabiec (Fuzzy Sets Syst. 125:385-389, 1989), we define a new G-contraction of Banach type with respect to this generalized fuzzy metric, which is a generalization of the contraction of Banach type (introduced by M Grabiec). Next, inspired by the ideas of Gregori and Sapena (Fuzzy Sets Syst. 125:245-252, 2002), we define a new GV-contraction of Banach type with respect to this generalized fuzzy metric, which is a generalization of the contraction of Banach type (introduced by V Gregori and A Sapena). Moreover, we provide the condition guaranteeing the existence of a fixed point for these single-valued contractions. Next, we show that the generalized pseudodistance J:X×X→[0,∞) (introduced by Włodarczyk and Plebaniak (Appl. Math. Lett. 24:325-328, 2011)) may generate some generalized fuzzy metric NJ on X. The paper includes also the comparison of our results with those existing in the literature

    Nemo: a computational tool for analyzing nematode locomotion

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    The nematode Caenorhabditis elegans responds to an impressive range of chemical, mechanical and thermal stimuli and is extensively used to investigate the molecular mechanisms that mediate chemosensation, mechanotransduction and thermosensation. The main behavioral output of these responses is manifested as alterations in animal locomotion. Monitoring and examination of such alterations requires tools to capture and quantify features of nematode movement. In this paper, we introduce Nemo (nematode movement), a computationally efficient and robust two-dimensional object tracking algorithm for automated detection and analysis of C. elegans locomotion. This algorithm enables precise measurement and feature extraction of nematode movement components. In addition, we develop a Graphical User Interface designed to facilitate processing and interpretation of movement data. While, in this study, we focus on the simple sinusoidal locomotion of C. elegans, our approach can be readily adapted to handle complicated locomotory behaviour patterns by including additional movement characteristics and parameters subject to quantification. Our software tool offers the capacity to extract, analyze and measure nematode locomotion features by processing simple video files. By allowing precise and quantitative assessment of behavioral traits, this tool will assist the genetic dissection and elucidation of the molecular mechanisms underlying specific behavioral responses.Comment: 12 pages, 2 figures. accepted by BMC Neuroscience 2007, 8:8

    Achieving sustainable aquaculture: Historical and current perspectives and future needs and challenges

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    Important operational changes that have gradually been assimilated and new approaches that are developing as part of the movement toward sustainable intensive aquaculture production systems are presented via historical, current, and future perspectives. Improved environmental and economic sustainability based on increased efficiency of production continues to be realized. As a result, aquaculture continues to reduce its carbon footprint through reduced greenhouse gas emissions. Reduced use of freshwater and land resources per unit of production, improved feed management practices as well as increased knowledge of nutrient requirements, effective feed ingredients and additives, domestication of species, and new farming practices are now being applied or evaluated. Successful expansion into culture of marine species, both off and on shore, offers the potential of substantial increases in sustainable intensive aquaculture production combined with integrative efforts to increase efficiency will principally contribute to satisfying the increasing global demand for protein and food security needs
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