1,480 research outputs found

    Performance evaluation and optimal design of supermarket refrigeration systems with supermarket model "SuperSim", Part I: Model description and validation

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    This is the post-print version of the final paper published in International Journal of Refrigeration. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2010 Elsevier B.V.Conventional supermarket refrigeration systems are responsible for considerable CO2 emissions due to high energy consumption and large quantities of refrigerant leakage. In the effort to conserve energy and reduce environmental impacts, an efficient design tool for the analysis, evaluation and comparison of the performance of alternative system designs and controls is required. This paper provides a description of the modelling procedure employed in the supermarket simulation model ‘SuperSim’ for the simulation of the performance of centralised vapour compression refrigeration systems and their interaction with the building envelope and HVAC systems. The model which has been validated against data from a supermarket has been used for the comparison of R404A and CO2 refrigeration systems and the optimisation of the performance of transcritical CO2 systems. These results are presented in Part II of the paper.DEFR

    Simulation of multi-deck medium temperature display cabinets with the integration of CFD and cooling coil models

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    This is the post-print version of the final paper published in Applied Energy. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2010 Elsevier B.V.In this paper, the model for the multi-deck medium temperature display cabinets is developed with the integration of CFD and cooling coil sub-models. The distributed method is used to develop the cooling coil model with the airside inputs from the outputs of the CFD model. Inversely, the airside outputs from the cooling coil model are used to update the boundary conditions of the CFD model. To validate this cabinet model, a multi-deck medium temperature display cabinet refrigerated with a secondary refrigerant cooling coil was selected as a prototype and mounted in an air conditioned chamber. Extensive tests were conducted at constant space air temperature and varied relative humilities. The cabinet model has been validated by comparing with the test results for the parameters of air at different locations of the flow path, and temperatures of refrigerant and food product, etc. The validated model is therefore used to explore and analyse the cabinet performance and control strategies at various operating and design conditions.DEFR

    In vitro influence of stem surface finish and mantle conformity on pressure generation in cemented hip arthroplasty

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    Background and purpose Under physiological loads, debonded cemented femoral stems have been shown to move within their cement mantle and generate a fluid pump that may facilitate peri-prosthetic osteolysis by pressurizing fluid and circulating wear debris. The long-term physiological loading of rough and polished tapered stems in vitro has shown differences in performance, with greater interface pressures generated by the rough stems. In this study we investigated the individual effects of stem surface finish, degree of mantle wear, and mode of loading on the stem pump mechanism

    An Improved Transit Measurement for a 2.4 R⊕ Planet Orbiting A Bright Mid-M Dwarf K2–28

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    We present a new Spitzer transit observation of K2–28b, a sub-Neptune (Rp = 2.45 ± 0.28 R⊕) orbiting a relatively bright (V_(mag) = 16.06, K_(mag) = 10.75) metal-rich M4 dwarf (EPIC 206318379). This star is one of only seven with masses less than 0.2 M⊙ known to host transiting planets, and the planet appears to be a slightly smaller analogue of GJ 1214b (2.85 ± 0.20 R⊕). Our new Spitzerobservations were taken two years after the original K2 discovery data and have a significantly higher cadence, allowing us to derive improved estimates for this planet's radius, semimajor axis, and orbital period, which greatly reduce the uncertainty in the prediction of near future transit times for the James Webb Space Telescope (JWST) observations. We also evaluate the system's suitability for atmospheric characterization with JWST and find that it is currently the only small (<3 R⊕) and cool (<600 K) planet aside from GJ 1214b with a potentially detectable secondary eclipse. We also note that this system is a favorable target for near-infrared radial velocity instruments on larger telescopes (e.g., the Habitable Planet Finder on the Hobby–Eberly Telescope), making it one of only a handful of small, cool planets accessible with this technique. Finally, we compare our results with the simulated catalog of the Transiting Exoplanet Survey Satellite (TESS) and find K2–28b to be representative of the kind of mid-M systems that should be detectable in the TESS sample

    In vitro comparison of the effects of rough and polished stem surface finish on pressure generation in cemented hip arthroplasty

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    Background and purpose High pressures around implants can cause bone lysis and loosening. We investigated how pressures are generated around cemented femoral stems

    Low-kinetic energy impact response of auxetic and conventional open-cell polyurethane foams

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    This paper reports quasi-static and low-kinetic energy impact testing of auxetic and conventional open-cell polyurethane foams. The auxetic foams were fabricated using the established thermo-mechanical process originally developed by Lakes. Converted foams were subject to compression along each dimension to 85% and 70% of the unconverted dimension during the conversion process, corresponding to linear compression ratios of 0.85 and 0.7, respectively. The 0.7 linear compression ratio foams were confirmed to have a re-entrant foam cell structure and to be auxetic. Impact tests were performed for kinetic energies up to 4 J using an instrumented drop rig and high speed video. A flat dropper was employed on isolated foams, and a hemisperical shaped dropper on foams covered with a rigid polypropylene outer shell layer. The flat dropper tests provide data on the rate-dependency of the Poisson’s ratio in these foam test specimens. The foam Poisson’s ratios were found to be unaffected by the strain rate for the impact energies considered here. Acceleration-time data are reported along with deformation images from the video footage. The auxetic samples displayed a 6 times reduction in peak acceleration, showing potential in impact protector devices such as shin or thigh protectors in sports equipment applications. Keywords : auxetic, foam, impact, negative Poisson’s rati

    Evo-devo of human adolescence: beyond disease models of early puberty

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    Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals. Utilizing evolutionary development biology (evo-devo), we examine adolescence as an evolutionary life-history stage in its developmental context. We show that the transition from the preceding stage of juvenility entails adaptive plasticity in response to energy resources, other environmental cues, social needs of adolescence and maturation toward youth and adulthood. Using the evolutionary theory of socialization, we show that familial psychosocial stress fosters a fast life history and reproductive strategy rather than early maturation being just a risk factor for aggression and delinquency. Here we explore implications of an evolutionary-developmental-endocrinological-anthropological framework for theory building, while illuminating new directions for research

    Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine

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    Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important role as effector agents of the innate immune system. The AMP era was born more than 6 decades ago when the first cationic cyclic peptide antibiotics, namely polymyxins and tyrothricin, found their way into clinical use. Due to the good clinical experience in the treatment of, for example, infections of mucus membranes as well as the subsequent understanding of mode of action, AMPs are now considered for treatment of inflammatory skin diseases and for improving healing of infected wounds. Based on the preclinical findings, including pathobiochemistry and molecular medicine, targeted therapy strategies are developed and first results indicate that AMPs influence processes of diseased skin. Importantly, in contrast to other antibiotics, AMPs do not seem to propagate the development of antibiotic-resistant micro-organisms. Therefore, AMPs should be tested in clinical trials for their efficacy and tolerability in inflammatory skin diseases and chronic wounds. Apart from possible fields of application, these peptides appear suited as an example of the paradigm of translational medicine for skin diseases which is today seen as a `two-way road' - from bench to bedside and backwards from bedside to bench. Copyright (c) 2012 S. Karger AG, Base

    The Evolution of Compact Binary Star Systems

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    We review the formation and evolution of compact binary stars consisting of white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). Binary NSs and BHs are thought to be the primary astrophysical sources of gravitational waves (GWs) within the frequency band of ground-based detectors, while compact binaries of WDs are important sources of GWs at lower frequencies to be covered by space interferometers (LISA). Major uncertainties in the current understanding of properties of NSs and BHs most relevant to the GW studies are discussed, including the treatment of the natal kicks which compact stellar remnants acquire during the core collapse of massive stars and the common envelope phase of binary evolution. We discuss the coalescence rates of binary NSs and BHs and prospects for their detections, the formation and evolution of binary WDs and their observational manifestations. Special attention is given to AM CVn-stars -- compact binaries in which the Roche lobe is filled by another WD or a low-mass partially degenerate helium-star, as these stars are thought to be the best LISA verification binary GW sources.Comment: 105 pages, 18 figure
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