27 research outputs found
Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2)
Get PDFWe demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic RNA silencing was target-specific and is a new tool for gene regulation and metabolic engineering studies in Streptomyces.Peer reviewe
Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in <em>Streptomyces coelicolor</em>.
No full textActive-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates
No full textActive-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates.
No full textSynthetic RNA Silencing of Actinorhodin Biosynthesis in <em>Streptomyces coelicolor</em> A3(2)
No full textWe demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic RNA silencing was target-specific and is a new tool for gene regulation and metabolic engineering studies in Streptomyces
Abyssomicin Biosynthesis: Formation of an Unusual Polyketide, Antibiotic-Feeding Studies and Genetic Analysis
No full textGenome Sequence of the Abyssomicin- and Proximicin-Producing Marine Actinomycete <em>Verrucosispora maris</em> AB-18-032
No full textAfrican Yam Bean the Choice for Climate Change Resilience: Need for Conservation and Policy
No full textIdentification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis
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