Gamble mode: Resonance contact mode in atomic force microscopy

Active noise reduction has been accomplished in atomic force microscopy by applying a high frequency, low amplitude vibration to the cantilever while it is in contact with a surface. The applied excitation (>~ 200 kHz; ~ 1 nm) is acoustically coupled to the tip and dampens the resonance Q factors of the system. The applied frequency is well above the bandwidth of the acquisition system (50 kHz). We call this mode "gamble mode" or "resonance contact.

Noise reduction in atomic force microscopy: Resonance contact mode

Noise reduction has been accomplished in atomic force microscopy by applying a high frequency, low amplitude vibration to the cantilever while it is in contact with a surface. The applied excitation (>~200 kHz; ~1 nm) is acoustically coupled to the tip and dampens the resonance Q factors of the system. The applied frequency is well above the bandwidth of the acquisition system (50 kHz). We call this mode "resonance contact" mode. The nonlinear behavior of the tip–sample interaction allows the high frequency excitation to effectively broaden the frequency response of the system resonances

Remotely controlled mirror of variable geometry for small angle x-ray diffraction with synchrotron radiation

A total-reflecting mirror of 120-cm length was designed and built to focus synchrotron radiation emanating from the electron-positron storage ring at the Stanford Linear Accelerator Center (SPEAR). The reflecting surface is of unpolished float glass. The bending and tilt mechanism allows very fine control of the curvature and selectability of the critical angle for wavelengths ranging from 0.5 to 3.0 Å. Elliptical curvature is used to minimize aberrations. The mirror is placed asymmetrically onto the ellipse so as to achieve a tenfold demagnification of the source. The bending mechanism reduces nonelastic deformation (flow) and minimizes strains and stresses in the glass despite its length. Special design features assure stability of the focused image. The mirror reduces the intensity of shorter wavelength harmonics by a factor of approximately 100

Calcium supplements with or without vitamin D and risk of cardiovascular events : reanalysis of the Women's Health Initiative limited access dataset and meta-analysis

Peer reviewedPublisher PD

A New Genus of Miniaturized and Pug-Nosed Gecko from South America (Sphaerodactylidae: Gekkota)

Sphaerodactyl geckos comprise five genera distributed across Central and South America and the Caribbean. We estimated phylogenetic relationships among sphaerodactyl genera using both separate and combined analyses of seven nuclear genes. Relationships among genera were incongruent at different loci and phylogenies were characterized by short, in some cases zero-length, internal branches and poor phylogenetic support at most nodes. We recovered a polyphyletic Coleodactylus, with Coleodactylus amazonicus being deeply divergent from the remaining Coleodactylus species sampled. The C. amazonicus lineage possessed unique codon deletions in the genes PTPN12 and RBMX while the remaining Coleodactylus species had unique codon deletions in RAG1. Topology tests could not reject a monophyletic Coleodactylus, but we show that short internal branch lengths decreased the accuracy of topology tests because there were not enough data along these short branches to support one phylogenetic hypothesis over another. Morphological data corroborated results of the molecular phylogeny, with Coleodactylus exhibiting substantial morphological heterogeneity. We identified a suite of unique craniofacial features that differentiate C. amazonicus not only from other Coleodactylus species, but also from all other geckos. We describe this novel sphaerodactyl lineage as a new genus, Chatogekko gen. nov. We present a detailed osteology of Chatogekko, characterizing osteological correlates of miniaturization that provide a framework for future studies in sphaerodactyl systematics and biology

The development and application of aerodynamic uncertainties: And flight test verification for the space shuttle orbiter

The approach used in establishing the predicted aerodynamic uncertainties and the process used in applying these uncertainties during the design of the Orbiter flight control system and the entry trajectories are presented. The flight test program that was designed to verify the stability and control derivatives with a minimum of test flights is presented and a comparison of preflight predictions with preliminary flight test results is made. It is concluded that the approach used for the Orbiter is applicable to future programs where testing is limited due to time constraints or funding

Making co-enrolment feasible for randomised controlled trials in paediatric intensive care.

Enrolling children into several trials could increase recruitment and lead to quicker delivery of optimal care in paediatric intensive care units (PICU). We evaluated decisions taken by clinicians and parents in PICU on co-enrolment for two large pragmatic trials: the CATCH trial (CATheters in CHildren) comparing impregnated with standard central venous catheters (CVCs) for reducing bloodstream infection in PICU and the CHIP trial comparing tight versus standard control of hyperglycaemia

ERTS-1 applications to Minnesota land use mapping

Land use class definitions that can be operationally employed with ERTS-1 imagery are being developed with the cooperation of personnel from several state, regional, and federal agencies with land management responsibilities within the state and the University of Minnesota. Investigations of urban, extractive, forest, and wetlands areas indicate that it is feasible to subdivide each of these classes into several sub-classes with the use of ERTS-1 images from one or more time periods

Calcium supplements and cancer risk : a meta-analysis of randomised controlled trials

Peer reviewedPublisher PD