Merging clusters of galaxies observed with XMM-Newton

We present results from the XMM-Newton observations of our ongoing program on merging clusters. To date three clusters have been observed, covering the temporal sequence from early to late stage mergers: A1750, A2065 and A3921. Using spatially-resolved spectroscopy of discrete regions, hardness ratio and temperature maps, we show that all three clusters display a complex temperature structure. In the case of A1750, a double cluster, we argue that the observed temperature structure is not only related to the ongoing merger but also to previous merger events. A2065 seems an excellent example of a `compact merger', i.e. when the centres of the two clusters have just started to interact, producing a shock in the ICM. Using comparisons with numerical simulations and complementary optical data, the highly complex temperature structure evident in A3921 is interpreted as an off-axis merger between two unequal mass components. These results illustrate the complex physics of merger events. The relaxation time can be larger than the typical time between merger events, so that the present day morphology of clusters depends not only on on-going interaction but also on the more ancient formation history.Comment: 10 pages, 3 figures. Use elsart.cls. Accepted for publication in Advances in Space Research. A version with full resolution figures can be found at http://www.star.bris.ac.uk/elena/cospar_3clusters.pd

Planets around active stars

We present the results of radial velocity measurements of two samples of active stars. The first sample contains field G and K giants across the Red Giant Branch, whereas the second sample consists of nearby young stars (d < 150 pc) with ages between 10 - 300 Myrs. The radial velocity monitoring program has been carried out with FEROS at 1.52 m ESO telescope (1999 - 2002) and continued since 2003 at 2.2 m MPG/ESO telescope. We observed stellar radial velocity variations which originate either from the stellar activity or the presence of stellar/substellar companions. By means of a bisector technique we are able to distinguish the sources of the radial velocity variation. Among them we found few candidates of planetary companions, both of young stars and G-K giants sample.Comment: 4 pages, 5 figures, to appear in the Proceedings of the ESO Workshop "Precision Spectroscopy in Astrophysics", eds. L. Pasquini, M. Romaniello, N.C. Santos, A. Correi

Vibrational Instability of Metal-Poor Low-Mass Main-Sequence Stars

We find that low-degree low-order g-modes become unstable in metal-poor low-mass stars due to the $\varepsilon$-mechanism of the pp-chain. Since the outer convection zone of these stars is limited only to the very outer layers, the uncertainty in the treatment of convection does not affect the result significantly. The decrease in metallicity leads to decrease in opacity and hence increase in luminosity of a star. This makes the star compact and results in decrease in the density contrast, which is favorable to the $\varepsilon$-mechanism instability. We find also instability for high order g-modes of metal-poor low-mass stars by the convective blocking mechanism. Since the effective temperature and the luminosity of metal-poor stars are significantly higher than those of Pop I stars, the stars showing $\gamma$ Dor-type pulsation are substantially less massive than in the case of Pop I stars. We demonstrate that those modes are unstable for about $1\,M_\odot$ stars in the metal-poor case.Comment: 4 pages, 4 figures, To be published in Astrophysics and Space Science Proceedings series (ASSP). Proceedings of the "20th Stellar Pulsation Conference Series: Impact of new instrumentation and new insights in stellar pulsations", 5-9 September 2011, Granada, Spai

Rolling Tachyon in Brane World Cosmology from Superstring Field Theory

The pressureless tachyonic matter recently found in superstring field theory has an over-abundance problem in cosmology. We argue that this problem is naturally solved in the brane inflationary scenario if almost all of the tachyon energy is drained (via its coupling to the inflaton and matter fields) to heating the universe, while the rest of the tachyon energy goes to a network of cosmic strings (lower-dimensional BPS D-branes) produced during the tachyon rolling at the end of inflation.Comment: 4 pages, one figure. This version quantifies constraints on various phenomenological models for tachyon deca

Kac-Moody algebras in perturbative string theory

The conjecture that M-theory has the rank eleven Kac-Moody symmetry e11 implies that Type IIA and Type IIB string theories in ten dimensions possess certain infinite dimensional perturbative symmetry algebras that we determine. This prediction is compared with the symmetry algebras that can be constructed in perturbative string theory, using the closed string analogues of the DDF operators. Within the limitations of this construction close agreement is found. We also perform the analogous analysis for the case of the closed bosonic string.Comment: 31 pages, harvmac (b), 4 eps-figure

Electromagnetic field correlations near a surface with a nonlocal optical response

The coherence length of the thermal electromagnetic field near a planar surface has a minimum value related to the nonlocal dielectric response of the material. We perform two model calculations of the electric energy density and the field's degree of spatial coherence. Above a polar crystal, the lattice constant gives the minimum coherence length. It also gives the upper limit to the near field energy density, cutting off its $1/z^3$ divergence. Near an electron plasma described by the semiclassical Lindhard dielectric function, the corresponding length scale is fixed by plasma screening to the Thomas-Fermi length. The electron mean free path, however, sets a larger scale where significant deviations from the local description are visible.Comment: 15 pages, 7 figure files (.eps), \documentclass[global]{svjour}, accepted in special issue "Optics on the Nanoscale" (Applied Physics B, eds. V. Shalaev and F. Tr\"ager

The Centurion 18 telescope of the Wise Observatory

We describe the second telescope of the Wise Observatory, a 0.46-m Centurion 18 (C18) installed in 2005, which enhances significantly the observing possibilities. The telescope operates from a small dome and is equipped with a large-format CCD camera. In the last two years this telescope was intensively used in a variety of monitoring projects. The operation of the C18 is now automatic, requiring only start-up at the beginning of a night and close-down at dawn. The observations are mostly performed remotely from the Tel Aviv campus or even from the observer's home. The entire facility was erected for a component cost of about 70k$ and a labor investment of a total of one man-year. We describe three types of projects undertaken with this new facility: the measurement of asteroid light variability with the purpose of determining physical parameters and binarity, the following-up of transiting extrasolar planets, and the study of AGN variability. The successful implementation of the C18 demonstrates the viability of small telescopes in an age of huge light-collectors, provided the operation of such facilities is very efficient.Comment: 16 pages, 13 figures, some figures quality was degraded, accepted for publication in Astrophysics and Space Scienc

Advances in Antisense Oligonucleotide Development for Target Identification, Validation, and as Novel Therapeutics

Antisense oligonucleotides (As-ODNs) are single stranded, synthetically prepared strands of deoxynucleotide sequences, usually 18–21 nucleotides in length, complementary to the mRNA sequence of the target gene. As-ODNs are able to selectively bind cognate mRNA sequences by sequence-specific hybridization. This results in cleavage or disablement of the mRNA and, thus, inhibits the expression of the target gene. The specificity of the As approach is based on the probability that, in the human genome, any sequence longer than a minimal number of nucleotides (nt), 13 for RNA and 17 for DNA, normally occurs only once. The potential applications of As-ODNs are numerous because mRNA is ubiquitous and is more accessible to manipulation than DNA. With the publication of the human genome sequence, it has become theoretically possible to inhibit mRNA of almost any gene by As-ODNs, in order to get a better understanding of gene function, investigate its role in disease pathology and to study novel therapeutic targets for the diseases caused by dysregulated gene expression. The conceptual simplicity, the availability of gene sequence information from the human genome, the inexpensive availability of synthetic oligonucleotides and the possibility of rational drug design makes As-ODNs powerful tools for target identification, validation and therapeutic intervention. In this review we discuss the latest developments in antisense oligonucleotide design, delivery, pharmacokinetics and potential side effects, as well as its uses in target identification and validation, and finally focus on the current developments of antisense oligonucleotides in therapeutic intervention in various diseases

Demonstration of the temporal matter-wave Talbot effect for trapped matter waves

We demonstrate the temporal Talbot effect for trapped matter waves using ultracold atoms in an optical lattice. We investigate the phase evolution of an array of essentially non-interacting matter waves and observe matter-wave collapse and revival in the form of a Talbot interference pattern. By using long expansion times, we image momentum space with sub-recoil resolution, allowing us to observe fractional Talbot fringes up to 10th order.Comment: 17 pages, 7 figure