442 research outputs found
Localisation and mass generation for non-Abelian gauge fields
It has been suggested recently that in the presence of suitably "warped"
extra dimensions, the low-energy limit of pure gauge field theory may contain
massive elementary vector bosons localised on a "brane", but no elementary
Higgs scalars. We provide non-perturbative evidence in favour of this
conjecture through numerical lattice measurements of the static quark-antiquark
force of pure SU(2) gauge theory in three dimensions, of which one is warped.
We consider also warpings leading to massless localised vector bosons, and
again find evidence supporting the perturbative prediction, even though the
gauge coupling diverges far from the brane in this case.Comment: 27 pages; small clarifications adde
Transient domain walls and lepton asymmetry in the Left-Right symmetric model
It is shown that the dynamics of domain walls in Left-Right symmetric models,
separating respective regions of unbroken SU(2)_L and SU(2)_R in the early
universe, can give rise to baryogenesis via leptogenesis. Neutrinos have a
spatially varying complex mass matrix due to CP-violating scalar condensates in
the domain wall. The motion of the wall through the plasma generates a flux of
lepton number across the wall which is converted to a lepton asymmetry by
helicity-flipping scatterings. Subsequent processing of the lepton excess by
sphalerons results in the observed baryon asymmetry, for a range of parameters
in Left-Right symmetric models.Comment: v2 version accepted for publication in Phys. Rev. D. Discussion in
Introduction and Conclusion sharpened. Equation (12) corrected. 16 pages, 3
figure files, RevTeX4 styl
Leptogenesis through direct inflaton decay to light particles
We present a scenario of nonthermal leptogenesis following supersymmetric
hybrid inflation, in the case where inflaton decay to both heavy right handed
neutrino and SU(2)_L triplet superfields is kinematically disallowed. Lepton
asymmetry is generated through the decay of the inflaton into light particles
by the interference of one-loop diagrams with right handed neutrino and SU(2)_L
triplet exchange respectively. We require superpotential couplings explicitly
violating a U(1) R-symmetry and R-parity. However, the broken R-parity need not
have currently observable low-energy signatures. Also, the lightest sparticle
can be stable. Some R-parity violating slepton decays may, though, be
detectable in the future colliders. We take into account the constraints from
neutrino masses and mixing and the preservation of the primordial lepton
asymmetry.Comment: 11 pages including 3 figures, uses Revtex, minor corrections,
references adde
Complex structure moduli stability in toroidal compactifications
In this paper we present a classification of possible dynamics of closed
string moduli within specific toroidal compactifications of Type II string
theories due to the NS-NS tadpole terms in the reduced action. They appear as
potential terms for the moduli when supersymmetry is broken due to the presence
of D-branes. We particularise to specific constructions with two, four and
six-dimensional tori, and study the stabilisation of the complex structure
moduli at the disk level. We find that, depending on the cycle on the compact
space where the brane is wrapped, there are three possible cases: i) there is a
solution inside the complex structure moduli space, and the configuration is
stable at the critical point, ii) the moduli fields are driven towards the
boundary of the moduli space, iii) there is no stable solution at the minimum
of the potential and the system decays into a set of branes.Comment: 24 pages, JHEP3.cls, 19 figures. A few references adde
Baryon number violation, baryogenesis and defects with extra dimensions
In generic models for grand unified theories(GUT), various types of baryon
number violating processes are expected when quarks and leptons propagate in
the background of GUT strings. On the other hand, in models with large extra
dimensions, the baryon number violation in the background of a string is not
trivial because it must depend on the mechanism of the proton stabilization. In
this paper we argue that cosmic strings in models with extra dimensions can
enhance the baryon number violation to a phenomenologically interesting level,
if the proton decay is suppressed by the mechanism of localized wavefunctions.
We also make some comments on baryogenesis mediated by cosmological defects. We
show at least two scenarios will be successful in this direction. One is the
scenario of leptogenesis where the required lepton number conversion is
mediated by cosmic strings, and the other is the baryogenesis from the decaying
cosmological domain wall. Both scenarios are new and have not been discussed in
the past.Comment: 20pages, latex2e, comments and references added, to appear in PR
Decay of Unstable D-branes with Electric Field
Using the techniques of two dimensional conformal field theory we construct
time dependent classical solutions in open string theory describing the decay
of an unstable D-brane in the presence of background electric field, and
explicitly evaluate the time dependence of the energy momentum tensor and the
fundamental string charge density associated with this solution. The final
decay product can be interpreted as a combination of stretched fundamental
strings and tachyon matter.Comment: 35 pages, LaTe
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis
Mutations in leucine-rich repeat kinase 2 (LRRK2) are an established cause of inherited Parkinson's disease (PD). LRRK2 is expressed in both neurons and glia in the central nervous system, but its physiological function(s) in each of these cell types is uncertain. Through sequential screens, we report a functional interaction between LRRK2 and Clathrin adaptor protein complex 2 (AP2). Analysis of LRRK2 KO tissue revealed a significant dysregulation of AP2 complex components, suggesting LRRK2 may act upstream of AP2. In line with this hypothesis, expression of LRRK2 was found to modify recruitment and phosphorylation of AP2. Furthermore, expression of LRRK2 containing the R1441C pathogenic mutation resulted in impaired clathrin-mediated endocytosis (CME). A decrease in activity-dependent synaptic vesicle endocytosis was also observed in neurons harboring an endogenous R1441C LRRK2 mutation. Alongside LRRK2, several PD-associated genes intersect with membrane-trafficking pathways. To investigate the genetic association between Clathrin-trafficking and PD, we used polygenetic risk profiling from IPDGC genome wide association studies (GWAS) datasets. Clathrin-dependent endocytosis genes were found to be associated with PD across multiple cohorts, suggesting common variants at these loci represent a cumulative risk factor for disease. Taken together, these findings suggest CME is a LRRK2-mediated, PD relevant pathway.Neurological Motor Disorder
Using the past to constrain the future: how the palaeorecord can improve estimates of global warming
Climate sensitivity is defined as the change in global mean equilibrium
temperature after a doubling of atmospheric CO2 concentration and provides a
simple measure of global warming. An early estimate of climate sensitivity,
1.5-4.5{\deg}C, has changed little subsequently, including the latest
assessment by the Intergovernmental Panel on Climate Change.
The persistence of such large uncertainties in this simple measure casts
doubt on our understanding of the mechanisms of climate change and our ability
to predict the response of the climate system to future perturbations. This has
motivated continued attempts to constrain the range with climate data, alone or
in conjunction with models. The majority of studies use data from the
instrumental period (post-1850) but recent work has made use of information
about the large climate changes experienced in the geological past.
In this review, we first outline approaches that estimate climate sensitivity
using instrumental climate observations and then summarise attempts to use the
record of climate change on geological timescales. We examine the limitations
of these studies and suggest ways in which the power of the palaeoclimate
record could be better used to reduce uncertainties in our predictions of
climate sensitivity.Comment: The final, definitive version of this paper has been published in
Progress in Physical Geography, 31(5), 2007 by SAGE Publications Ltd, All
rights reserved. \c{opyright} 2007 Edwards, Crucifix and Harriso
Thermal leptogenesis in a model with mass varying neutrinos
In this paper we consider the possibility of neutrino mass varying during the
evolution of the Universe and study its implications on leptogenesis.
Specifically, we take the minimal seesaw model of neutrino masses and introduce
a coupling between the right-handed neutrinos and the dark energy scalar field,
the Quintessence. In our model, the right-handed neutrino masses change as the
Quintessence scalar evolves. We then examine in detail the parameter space of
this model allowed by the observed baryon number asymmetry. Our results show
that it is possible to lower the reheating temperature in this scenario in
comparison with the case that the neutrino masses are unchanged, which helps
solve the gravitino problem. Furthermore, a degenerate neutrino mass patten
with larger than the upper limit given in the minimal leptogenesis
scenario is permitted.Comment: 18 pages, 7 figures, version to appear in PR
Boundary work: becoming middle class in suburban Dar es Salaam
Suburban space provides a useful window onto contemporary class practices in Africa, where it is difficult to identify social classes on the basis of income or occupation. In this article I argue that the middle classes and the suburbs are mutually constitutive in the Tanzanian city of Dar es Salaam. Using interviews with residents and local government officials in the city's northern suburbs, I discuss the material and representational practices of middle-class boundary work in relation to land and landscape. If the middle classes do not presently constitute a coherent political-economic force, they are nevertheless transforming the city's former northern peri-urban zones into desirable suburban residential neighbourhoods
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