18 research outputs found

    The Non-Trivial Effective Potential of the `Trivial' lambda Phi^4 Theory: A Lattice Test

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    The strong evidence for the `triviality' of (lambda Phi^4)_4 theory is not incompatible with spontaneous symmetry breaking. Indeed, for a `trivial' theory the effective potential should be given exactly by the classical potential plus the free-field zero-point energy of the shifted field; i.e., by the one-loop effective potential. When this is renormalized in a simple, but nonperturbative way, one finds, self-consistently, that the shifted field does become non-interacting in the continuum limit. For a classically scale-invariant (CSI) lambda Phi^4 theory one finds m_h^2 = 8 pi^2 v^2, predicting a 2.2 TeV Higgs boson. Here we extend our earlier work in three ways: (i) we discuss the analogy with the hard-sphere Bose gas; (ii) we extend the analysis from the CSI case to the general case; and (iii) we propose a test of the predicted shape of the effective potential that could be tested in a lattice simulation.Comment: 22 pages, LaTeX, DE-FG05-92ER40717-

    The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

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    BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

    A Neural Network for Spatial and Temporal Modeling of foF2 Data Based on Satellite Measurements

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    Part 6: Classification Pattern RecognitionInternational audienceThis paper presents the application of Neural Networks for the spatial and temporal modeling of (critical frequency) foF2 data over Europe. foF2 is the most important parameter in describing the electron density profile of the ionosphere since it represents the critical point of maximum electron density in the profile and therefore can be used to drive empirical models of electron density which incorporate foF2 as an anchor point in the profile shape. The model is based on radio occultation (RO) measurements by LEO (Low Earth Orbit) satellites which provide excellent spatial coverage of foF2 measurements
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