1,802 research outputs found

    Comparison between an integral and algebraic formulation for the eddy diffusivity using the Copenhagen experimental dataset

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    In this work an algebraic formulation to evaluate the eddy diffusivities in the Convective Boundary Layer (CBL) is derived. The expression depends on the turbulence properties (z height dependence) and the distance from the source. It is based on the turbulent kinetic energy spectra and Taylor’s statistical diffusion theory. It has been tested and compared through an experimental dataset, with another complex integral formulation taken from the literature. The Agreement between the complex integral formulation and simple algebraic expression points out that this new parameterization is valid and can be used as a surrogate for eddy diffusivities in the inhomogeneous convective turbulence present in the CBL. The validation shows that the proposed algebraic vertical eddy diffusivity is suitable for application in advanced air quality regulatory models

    The Association of Compact Groups of Galaxies with Large-scale Structures

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    We use various samples of compact groups (CGs) to examine the types of association CGs have with rich and poor clusters of galaxies at low (z~0.04) and intermediate (z~0.1) redshifts. We find that ~10-20 % of CGs are associated with rich clusters and a much larger fraction with poorer clusters or loose groups. Considering the incompleteness of catalogs of poorer systems at intermediate redshift, our result is consistent with all CGs at intermediate redshift being associated with larger-scale systems. The richness of the clusters associated with CGs significantly increases from z~0.04 to z~0.1, while their Bautz-Morgan type changes from early to late type for the same range in z. Neither trend is compatible with a selection effect in the cluster catalogs used. We find earlier morphological types of galaxies to be more frequent in CGs associated with larger-scale structures, compared to those in CGs not associated to such structures. We consider this as new evidence that CGs are part of the large-scale structure formation process and that they may play an important role in the evolution of galaxies in these structures.Comment: 5 pages, no figures, Proc. ESO Workshop "Groups of galaxies in the nearby Universe", Santiago, Chile, 5-9 Dec. 2005, ESO Astrophysics Symposia, eds. I. Saviane, V. Ivanov & J. Borissova, Springer-Verlag; very minor revision of text on 15 Mar 2006, added one referenc

    Fermentation characteristics and chemical composition of elephant grass silage with ground maize and fermented juice of epiphytic lactic acid bacteria

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    This study aimed to evaluate the microbial populations, fermentation profile, dry matter recovery and chemical composition of elephant grass silage with ground maize (GM) and the fermented juice of epiphytic lactic acid bacteria (FJLB). A factorial design was used with four levels of GM (0 g/kg, 50 g/kg, 100 g/kg and 200 g/kg), untreated or treated with FJLB, in a completely randomized design with five replicates. A pre-experiment was undertaken to determine the optimum level of sucrose to be added to fermented juice for the development of epiphytic microflora. In this pre-experiment, a completely randomized design with three replications was used. The treatments were represented by the levels of sucrose (0 g/kg, 5 g/kg, 10 g/kg, 20 g/kg, 40 g/kg, 60 g/kg and 80 g/kg, fresh matter basis). The microbial populations, dry matter recovery, and effluent losses were affected by the interaction between GM and FJLB. Dry matter (DM) and crude protein (CP) contents increased linearly with the inclusion of GM. The addition of GM enhanced the fermentation process via a reduction in losses, and improvements were identified in the nutritional value of elephant grass silages. The use of fermented juice increased dry matter recovery, and its effect was more pronounced when ground maize was added.Keywords: dry matter recovery, lactic acid, microbiology, Pennisetum purpureu

    NMD inhibition fails to identify tumour suppressor genes in microsatellite stable gastric cancer cell lines

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    BACKGROUND: Gastric cancers frequently show chromosomal alterations which can cause activation of oncogenes, and/or inactivation of tumour suppressor genes. In gastric cancer several chromosomal regions are described to be frequently lost, but for most of the regions, no tumour suppressor genes have been identified yet. The present study aimed to identify tumour suppressor genes inactivated by nonsense mutation and deletion in gastric cancer by means of GINI (gene identification by nonsense mediated decay inhibition) and whole genome copy number analysis. METHODS: Two non-commercial gastric cancer cell lines, GP202 and IPA220, were transfected with siRNA directed against UPF1, to specifically inhibit the nonsense mediated decay (NMD) pathway, and with siRNA directed against non-specific siRNA duplexes (CVII) as a control. Microarray expression experiments were performed in triplicate on 4 Ă— 44 K Agilent arrays by hybridizing RNA from UPF1-transfected cells against non-specific CVII-transfected cells. In addition, array CGH of the two cell lines was performed on 4 Ă— 44K agilent arrays to obtain the DNA copy number profiles. Mutation analysis of GINI candidates was performed by sequencing. RESULTS: UPF1 expression was reduced for >70% and >80% in the GP202 and IPA220 gastric cancer cell lines, respectively. Integration of array CGH and microarray expression data provided a list of 134 and 50 candidate genes inactivated by nonsense mutation and deletion for GP202 and IPA220, respectively. We selected 12 candidate genes for mutation analysis. Of these, sequence analysis was performed on 11 genes. One gene, PLA2G4A, showed a silent mutation, and in two genes, CTSA and PTPRJ, missense mutations were detected. No nonsense mutations were detected in any of the 11 genes tested. CONCLUSION: Although UPF1 was substantially repressed, thus resulting in the inhibition of the NMD system, we did not find genes inactivated by nonsense mutations. Our results show that the GINI strategy leads to a high number of false positives

    Statistical Theory for Incoherent Light Propagation in Nonlinear Media

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    A novel statistical approach based on the Wigner transform is proposed for the description of partially incoherent optical wave dynamics in nonlinear media. An evolution equation for the Wigner transform is derived from a nonlinear Schrodinger equation with arbitrary nonlinearity. It is shown that random phase fluctuations of an incoherent plane wave lead to a Landau-like damping effect, which can stabilize the modulational instability. In the limit of the geometrical optics approximation, incoherent, localized, and stationary wave-fields are shown to exist for a wide class of nonlinear media.Comment: 4 pages, REVTeX4. Submitted to Physical Review E. Revised manuscrip
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