Bearings-Only Guidance in Cis-Lunar Rendezvous

The current plans of returning to the Moon involve rendezvous and docking/berthing operations with a passive permanent station, whose targeted orbit is a Near Rectilinear Halo Orbit. In this work a preliminary guidance algorithm for the close-range rendezvous phase is proposed, based on a sample mission application, assuming the active chaser can measure relative angles only to the target. The navigation performance is affected by the maneuvers performed because their execution is necessary to make the problem observable. The relative motion equations with third body perturbation are considered directly in the guidance algorithm, with the additional aim of improving observability during the approach trajectory. Numerical simulations are presented to validate the proposed methodology

Aids and surgery

HIV constitutes one of the most difficult challenges facing the healthcare profession today. It is estimated that HIV infects over 40 million people in the world and 14 million have died from the disease so far. The objective of the study was to evaluate the outcome of treatment of HIV-related surgical conditions, estimating the morbidity and mortality of surgical intervention cross infection risks to surgical equipes and analysing preventive strategies to HIV perioperative transmission

The Interval Kicking Program (IKP) as a Reprogramming Technique for the Soccer Player in an Anterior Cruciate Ligament (ACL) Rehabilitation: A Technical Report

Introduction. We can state as technical-athletic gestural movements that we might call clinical (pivoting, cutting maneuvers, sidestep cuts, changes of direction) associated with ACL injuries. Objective. This technical report was conducted to research methods of reprogramming basic technical skills in the soccer player after anterior cruciate ligament reconstructive surgery. Technical report results. The Interval Kicking Program (IKP) is a model proposed as a neuromotor remodelling of basic gestures and techniques after an ACL injury in soccer player. The teaching progression is ordered regarding the diversified techniques of passing and receiving the ball. The volume, intensity, and progression steps are governed by 1) clinical status (i.e., type of injury, conservative/surgical treatment type, type of sport), 2) performance status, and 3) objective evaluative analysis of periodic follow-ups. The steps provid-ed by the IKP can be 15 and end with the introduction of the player into technical drills with the presence of opponents the first sessions include about 30 minutes of sport-specific, low-intensity exercises, while in the last ones, the volume remains constant, but the intensity and technical complexity of the movements increase. Conclusions. In this technical report, we have highlighted how IKP can be a teaching model for reprogramming basic technical skills in the soccer player after injury. It remains fair to point out how aberrant technical movement partners, side-to-side asymmetries, and postur-al dysfunction are predictive of the risk of compliance and second injury. Further studies and insights are needed to customize the reprogramming of the soccer player’s gestural movements during return to play. © 2023, EDRA S.p.A. All rights reserved

Il ruolo degli effetti di sito sulla risposta strutturale degli edifici nella conca aquilana

Il terremoto de L’Aquila del 6 aprile 2009 è stato significativamente caratterizzato dagli effetti di sito, evidenziati sia dalla variabilità delle registrazioni accelerometriche in zona near fault che dalla disuniforme distribuzione del danno rilevato. In particolare, nel quartiere aquilano di Pettino, in corrispondenza di un complesso residenziale composto da sette edifici della stessa tipologia strutturale, è stato osservato un danneggiamento molto diversificato. La nota riporta i risultati di una serie di analisi di risposta sismica locale 1D, condotte in corrispondenza di alcuni degli edifici del quartiere, per i quali si disponeva di indagini geotecniche di dettaglio, finalizzate a valutare l’influenza degli effetti di sito sulla risposta delle strutture. I risultati delle analisi condotte in condizioni di campo libero hanno mostrato significative amplificazioni del moto proprio in corrispondenza delle frequenze fondamentali del moto di input. Le analisi del sistema sottosuolo-edificio, condotte mediante l’utilizzo di un codice con formulazione a masse concentrate hanno inoltre consentito di verificare l’incidenza dell’interazione inerziale sul moto in superficie, nonché di riprodurre in forma semplificata il meccanismo di piano soffice osservato

Milk Metabolomics Reveals Potential Biomarkers for Early Prediction of Pregnancy in Buffaloes Having Undergone Artificial Insemination.

This study aimed to identify potential biomarkers for early pregnancy diagnosis in buffaloes subjected to artificial insemination (AI). The study was carried out on 10 pregnant and 10 non-pregnant buffaloes that were synchronized by Ovsynch-Timed Artificial Insemination Program and have undergone the first AI. Furthermore, milk samples were individually collected ten days before AI (the start of the synchronization treatment), on the day of AI, day 7 and 18 after AI, and were analyzed by LC–MS. Statistical analysis was carried out by using Mass Profile Professional (Agilent Technologies, Santa Clara, CA, USA). Metabolomic analysis revealed the presence of several metabolites differentially expressed between pregnant and non-pregnant buffaloes. Among these, a total of five metabolites were identified by comparison with an online database and a standard compound as acetylcarnitine (3-Acetoxy-4-(trimethylammonio)butanoate), argininesuccinic acid hydrate, 5’-O-{[3-({4-[(3aminopropyl)amino]butyl}amino)propyl]carbamoyl}-2’deoxyadenosine, N-(1-Hydroxy-2-hexadecanyl)pentadecanamide, and N-[2,3Bis(dodecyloxy)propyl]-L-lysinamide). Interestingly, acetylcarnitine was dominant in milk samples collected from non-pregnant buffaloes. The results obtained from milk metabolic profile and hierarchical clustering analysis revealed significant differences between pregnant and non-pregnant buffaloes, as well as in the metabolite expression. Overall, the findings indicate the potential of milk metabolomics as a powerful tool to identify biomarkers of early pregnancy in buffalo undergoing AI

Redshift-Distance Survey of Early-type Galaxies. I. Sample Selection, Properties and Completeness

This is the first in a series of papers describing the recently completed all-sky redshift-distance survey of nearby early-type galaxies (ENEAR) carried out for peculiar velocity analysis. The sample is divided into two parts and consists of 1607 elliptical and lenticular galaxies with cz < 7000 km/s and with blue magnitudes brighter than m_B=14.5 (ENEARm), and of galaxies in clusters (ENEARc). Galaxy distances based on the Dn-sigma and Fundamental Plane (FP) relations are now available for 1359 and 1107 ENEARm galaxies, respectively, with roughly 80% based on new data gathered by our group. The Dn-sigma and FP template distance relations are derived by combining 569 and 431 galaxies in 28 clusters, respectively, of which about 60% are based on our new measurements. The ENEARm redshift-distance survey extends the earlier work of the 7S and the recent Tully-Fisher surveys sampling a comparable volume. In subsequent papers of this series we intend to use the ENEAR sample by itself or in combination with the SFI Tully-Fisher survey to analyze the properties of the local peculiar velocity field and to test how sensitive the results are to different sampling and to the distance indicators. We also anticipate that the homogeneous database assembled will be used for a variety of other applications and serve as a benchmark for similar studies at high-redshift.Comment: 43 pages, 15 figures, submitted to the Astronomical Journa

Energy and environmental aspects of mobile communication systems

The reduction of the energy consumptions of a Telecommunication Power System represents one of the critical factors of the telecommunication technologies, both to allow a sizeable saving of economic resources and to realize "sustainable" development actions. The consumption of about one hundred base stations for mobile phones were monitored for a total of over one thousand days, in order to study the energy consumption in relation to the environmental, electric and logistics parameters of the stations themselves. It was possible to survey, then, the role of the mobile communication systems in the general national energy framework and to plot the best areas of intervention for saving energy and improving the environmental impact, showing the role played by air conditioning and transmission equipments. Finally, new transmission algorithms and the use of renewable energy based techniques have been tested.Comment: 9 pages, 6 figure

An ontology-based approach for modelling and querying Alzheimer’s disease data

Background The recent advances in biotechnology and computer science have led to an ever-increasing availability of public biomedical data distributed in large databases worldwide. However, these data collections are far from being "standardized" so to be harmonized or even integrated, making it impossible to fully exploit the latest machine learning technologies for the analysis of data themselves. Hence, facing this huge flow of biomedical data is a challenging task for researchers and clinicians due to their complexity and high heterogeneity. This is the case of neurodegenerative diseases and the Alzheimer's Disease (AD) in whose context specialized data collections such as the one by the Alzheimer's Disease Neuroimaging Initiative (ADNI) are maintained.Methods Ontologies are controlled vocabularies that allow the semantics of data and their relationships in a given domain to be represented. They are often exploited to aid knowledge and data management in healthcare research. Computational Ontologies are the result of the combination of data management systems and traditional ontologies. Our approach is i) to define a computational ontology representing a logic-based formal conceptual model of the ADNI data collection and ii) to provide a means for populating the ontology with the actual data in the Alzheimer Disease Neuroimaging Initiative (ADNI). These two components make it possible to semantically query the ADNI database in order to support data extraction in a more intuitive manner.Results We developed: i) a detailed computational ontology for clinical multimodal datasets from the ADNI repository in order to simplify the access to these data; ii) a means for populating this ontology with the actual ADNI data. Such computational ontology immediately makes it possible to facilitate complex queries to the ADNI files, obtaining new diagnostic knowledge about Alzheimer's disease.Conclusions The proposed ontology will improve the access to the ADNI dataset, allowing queries to extract multivariate datasets to perform multidimensional and longitudinal statistical analyses. Moreover, the proposed ontology can be a candidate for supporting the design and implementation of new information systems for the collection and management of AD data and metadata, and for being a reference point for harmonizing or integrating data residing in different sources

The Extragalactic Distance Scale Key Project XXVII. A Derivation of the Hubble Constant Using the Fundamental Plane and Dn-Sigma Relations in Leo I, Virgo, and Fornax

Using published photometry and spectroscopy, we construct the fundamental plane and D_n-Sigma relations in Leo I, Virgo and Fornax. The published Cepheid P-L relations to spirals in these clusters fixes the relation between angular size and metric distance for both the fundamental plane and D_n-Sigma relations. Using the locally calibrated fundamental plane, we infer distances to a sample of clusters with a mean redshift of cz \approx 6000 \kms, and derive a value of H_0=78+- 5+- 9 km/s/Mpc (random, systematic) for the local expansion rate. This value includes a correction for depth effects in the Cepheid distances to the nearby clusters, which decreased the deduced value of the expansion rate by 5% +- 5%. If one further adopts the metallicity correction to the Cepheid PL relation, as derived by the Key Project, the value of the Hubble constant would decrease by a further 6%+- 4%. These two sources of systematic error, when combined with a +- 6% error due to the uncertainty in the distance to the Large Magellanic Cloud, a +- 4% error due to uncertainties in the WFPC2 calibration, and several small sources of uncertainty in the fundamental plane analysis, combine to yield a total systematic uncertainty of +- 11%. We find that the values obtained using either the CMB, or a flow-field model, for the reference frame of the distant clusters, agree to within 1%. The Dn-Sigma relation also produces similar results, as expected from the correlated nature of the two scaling relations. A complete discussion of the sources of random and systematic error in this determination of the Hubble constant is also given, in order to facilitate comparison with the other secondary indicators being used by the Key Project.Comment: 21 pages, 3 figures, Accepted for publication in Ap