The high-energy gamma-ray light curve of PSR B1259 -63

The high-energy gamma-ray light curve of the binary system PSR B1259 -63, is computed using the approach that successfully predicted the spectrum at periastron. The simultaneous INTEGRAL and H.E.S.S. spectra taken 16 days after periastron currently permit both a model with dominant radiative losses, high pulsar wind Lorentz factor and modest efficiency as well as one with dominant adiabatic losses, a slower wind and higher efficiency. In this paper we shown how the long-term light curve may help to lift this degeneracy.Comment: 4 pages, to appear in proceedings of: Astrophysical Sources of High Energy Particles and Radiation, Torun (2005

Supporting children and young people to assume responsibility from their parents for the self-management of their long-term condition: An integrative review

© 2019 John Wiley & Sons Ltd Background: Children and young people with long-term conditions (LTCs) are usually dependent on, or share management with, their families and are expected to develop self-management skills as they mature. However, during adolescence, young people can find it challenging to follow prescribed treatment regimens resulting in poor clinical outcomes. Though reviews have looked at children's and parents' experiences of self-management, none have explicitly examined the parent-to-child transfer of self-management responsibility. Methods: An integrative review was conducted with the aim of exploring the parent-to-child transfer of LTC self-management responsibility, through addressing two questions: (a) How do children assume responsibility from their parents for self-management of their LTC? (b) What influences the parent-to-child transfer of this responsibility? Eight databases were searched for papers published from 1995 to 2017. Methodological quality was assessed; included papers were synthesized to identify themes. Results: Twenty-nine papers were identified. Most papers used qualitative designs and focused on children with diabetes. Participants were predominantly children and/or parents; only two studies included health professionals. Assuming self-management responsibility was viewed as part of normal development but was rarely explored within the context of the child gaining independence in other areas of their life. Children and parents adopted strategies to help the transfer, but there was limited evidence around health professionals' roles and ambivalence around what was helpful. There was a lack of clarity over whether children and parents were aiming for shared management, or self-management, and whether this was a realistic or desired goal for families. Multiple factors such as the child, family, social networks, health professional, and LTC influenced how a child assumed responsibility. Conclusions: Evidence suggests that the parent-to-child transfer of self-management responsibility is a complex, individualized process. Further research across childhood LTCs is needed to explore children's, parents', and professionals' views on this process and what support families require as responsibilities change

Failure of non-vacuum steam sterilization processes for dental handpieces

Background: Dental handpieces are used in critical and semi-critical operative interventions. Although a number of dental professional bodies recommend that dental handpieces are sterilized between patient use there is a lack of clarity and understanding of the effectiveness of different steam sterilization processes. The internal mechanisms of dental handpieces contain narrow lumens (0·8-2·3mm) which can impede the removal of air and ingress of saturated steam required to achieve sterilization conditions. Aim: To identify the extent of sterilization failure in dental handpieces using a non-vacuum process. Methods: In-vitro and in-vivo investigations were conducted on commonly used UK benchtop steam sterilizers and three different types of dental handpieces. The sterilization process was monitored inside the lumens of dental handpieces using thermometric (TM) methods (dataloggers), chemical indicators (CI) and biological indicators (BI). Findings: All three methods of assessing achievement of sterility within dental handpieces that had been exposed to non-vacuum sterilization conditions demonstrated a significant number of failures (CI=8/3,024(fails/n tests); BI=15/3,024; TM=56/56) compared to vacuum sterilization conditions (CI=2/1,944; BI=0/1,944; TM=0/36). The dental handpiece most likely to fail sterilization in the non-vacuum process was the surgical handpiece. Non-vacuum sterilizers located in general dental practice had a higher rate of sterilization failure (CI=25/1,620; BI=32/1,620; TM=56/56) with no failures in vacuum process. Conclusion: Non-vacuum downward/gravity displacement, type-N steam sterilizers are an unreliable method for sterilization of dental handpieces in general dental practice. The handpiece most likely to fail sterilization is the type most frequently used for surgical interventions

Investigating steam penetration using thermometric methods in dental handpieces with narrow internal lumens during sterilizing processes with non-vacuum or vacuum processes

Background: Dental handpieces are required to be sterilized between patient use. Vacuum steam sterilization processes with fractionated pre/post-vacuum phases or unique cycles for specified medical devices, are required for hollow instruments with internal lumens to assure successful air removal. Entrapped air will compromise achievement of required sterilization conditions. Many countries and professional organisations still advocate non-vacuum sterilization processes for these devices. Aim: To investigate non-vacuum downward/gravity displacement, type-N steam sterilization of dental handpieces, using thermometric methods to measure time to achieve sterilization temperature at different handpiece locations. Methods: Measurements at different positions within air turbines were undertaken with thermocouples and dataloggers. Two examples of commonly used UK benchtop steam sterilizers were tested; a non-vacuum benchtop sterilizer (Little Sister 3, Eschmann, UK) and a vacuum benchtop sterilizer (Lisa, W&H, Austria). Each sterilizer cycle was completed with three handpieces and each cycle in triplicate. Findings: A total of 140 measurements inside dental handpiece lumens were recorded. We demonstrate that the non-vacuum process fails (time range 0-150 seconds) to reliably achieve sterilization temperatures within the time limit specified by the International standard (15 seconds equilibration time). The measurement point at the base of the handpiece failed in all test runs (n=9) to meet the standard. No failures were detected with the vacuum steam sterilization type B process with fractionated pre-vacuum and post-vacuum phases. Conclusion: Non-vacuum downward/gravity displacement, type-N steam sterilization processes are unreliable in achieving sterilization conditions inside dental handpieces and the base of the handpiece is the site most likely to fail

Complex X-ray spectral variability in Mkn 421 observed with XMM-Newton

The bright blazar Mkn 421 has been observed four times for uninterrupted durations of ~ 9 - 13 hr during the performance verification and calibration phases of the XMM-Newton mission. The source was strongly variable in all epochs, with variability amplitudes that generally increased to higher energy bands. Although the detailed relationship between soft (0.1 - 0.75 keV) and hard (2 - 10 keV) band differed from one epoch to the next, in no case was there any evidence for a measurable interband lag, with robust upper limits of $| \tau | < 0.08$ hr in the best-correlated light curves. This is in conflict with previous claims of both hard and soft lags of ~1 hr in this and other blazars. However, previous observations suffered a repeated 1.6 hr feature induced by the low-Earth orbital period, a feature that is not present in the uninterrupted XMM-Newton data. The new upper limit on $|\tau|$ leads to a lower limit on the magnetic field strength and Doppler factor of B \delta^{1/3} \gs 4.7 G, mildly out of line with the predictions from a variety of homogeneous synchrotron self-Compton emission models in the literature of $B \delta^{1/3} = 0.2 - 0.8$ G. Time-dependent spectral fitting was performed on all epochs, and no detectable spectral hysteresis was seen. We note however that the source exhibited significantly different spectral evolutionary behavior from one epoch to the next, with the strongest correlations in the first and last and an actual divergance between soft and hard X-ray bands in the third. This indicates that the range of spectral variability behavior in Mkn 421 is not fully described in these short snippets; significantly longer uninterrupted light curves are required, and can be obtained with XMM-Newton.Comment: 21 pages, 4 figures, accepted for ApJ, scheduled for August 1, 200

Electrical current distribution across a metal-insulator-metal structure during bistable switching

Combining scanning electron microscopy (SEM) and electron-beam-induced current (EBIC) imaging with transport measurements, it is shown that the current flowing across a two-terminal oxide-based capacitor-like structure is preferentially confined in areas localized at defects. As the thin-film device switches between two different resistance states, the distribution and intensity of the current paths, appearing as bright spots, change. This implies that switching and memory effects are mainly determined by the conducting properties along such paths. A model based on the storage and release of charge carriers within the insulator seems adequate to explain the observed memory effect.Comment: 8 pages, 7 figures, submitted to J. Appl. Phy

Direct observation of size scaling and elastic interaction between nano-scale defects in collision cascades

Using in-situ transmission electron microscopy, we have directly observed nano-scale defects formed in ultra-high purity tungsten by low-dose high energy self-ion irradiation at 30K. At cryogenic temperature lattice defects have reduced mobility, so these microscope observations offer a window on the initial, primary damage caused by individual collision cascade events. Electron microscope images provide direct evidence for a power-law size distribution of nano-scale defects formed in high-energy cascades, with an upper size limit independent of the incident ion energy, as predicted by Sand et al. [Eur. Phys. Lett., 103:46003, (2013)]. Furthermore, the analysis of pair distribution functions of defects observed in the micrographs shows significant intra-cascade spatial correlations consistent with strong elastic interaction between the defects

X-Ray Spectral Variability of PKS 2005-489 During the Spectacular November 1998 Flare

We report on monitoring of the BL Lac object PKS 2005-489 by the Rossi X-ray Timing Explorer (RXTE) in October-December 1998. During these months, the source underwent a spectacular flare; at its peak on November 10, its 2-10 keV flux was $3.33 \times 10^{-10} {\rm ~erg ~cm^{-2} ~s^{-1}}$, over 30 times brighter than in quiescence. During the rising phase, the X-ray spectrum of PKS 2005-489 hardened considerably, reaching $\alpha = 1.32~ (F_\nu \propto \nu^{-\alpha})$ near maximum. During the declining phase, the X-ray spectrum steepened rapidly, reaching $\alpha = 1.82$, then became somewhat harder towards the end of December ($\alpha \sim 1.6$). While such behavior has been seen before, the simplicity, magnitude and duration of this flare allowed us to study it in great detail. We argue that this flare was caused by either the injection of particles into the jet or {\it in situ} particle acceleration, and that the spectral steepening which followed the flare maximum was the result of synchrotron cooling. Contrary to other recently observed blazar flares (e.g., Mkn 501, 3C 279, PKS 2155-304), our results do not imply a major shift in the location of the synchrotron peak during this flare.Comment: ApJ Letters in press, 6 pages, 2 figures Corrected reference

Gamma-rays from PSR B1259 -63

The high-energy gamma-ray emission discovered using the H.E.S.S. telescopes from the binary system PSR B1259 -63, is modelled using an extension of the approach that successfully predicted it. We find that the simultaneous INTEGRAL and H.E.S.S. data permit both a model with dominant radiative losses, high pulsar wind Lorentz factor and modest efficiency as well as one with dominant adiabatic losses, a slower wind and higher efficiency. Additional, simultaneous, X-ray and TeV data sets are needed to lift this degeneracy.Comment: 4 pages, to appear in: Proceedings of the 29th International Cosmic Ray Conference, Pune (2005