512 research outputs found

    Geografia e televisione: dagli spazi locali agli spazi globali

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    Il rapporto tra geografia e televisione \ue8 un campo di studio ancora troppo poco esplorato. La comunicazione televisiva ha portato alla globalizzazione dei mercati e delle idee e, contemporaneamente, ha rafforzato le culture locali. La domanda \ue8 allora, per i geografi, se la televisione pu\uf2 aiutare ad abbattere le frontiere o se, al contrario, contribuisce a rafforzare i confini determinati da vincoli di identit\ue0 culturale. The relationship between Geography and Television is a field of study still too little explored. The television communication has led to the globalization of markets and of ideas and, simultaneously, has reinforced local cultures The question is then, to geographers, if television can help to tear down the borders or whether, on the contrary, contributes to strengthen the boundaries affected by ties of cultural identity

    Optical and electrical recording of neural activity evoked by graded contrast visual stimulus

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    BackgroundBrain activity has been investigated by several methods with different principles, notably optical ones. Each method may offer information on distinct physiological or pathological aspects of brain function. The ideal instrument to measure brain activity should include complementary techniques and integrate the resultant information. As a "low cost" approach towards this objective, we combined the well-grounded electroencephalography technique with the newer near infrared spectroscopy methods to investigate human visual function.MethodsThe article describes an embedded instrumentation combining a continuous-wave near-infrared spectroscopy system and an electroencephalography system to simultaneously monitor functional hemodynamics and electrical activity. Near infrared spectroscopy (NIRS) signal depends on the light absorption spectra of haemoglobin and measures the blood volume and blood oxygenation regulation supporting the neural activity. The NIRS and visual evoked potential (VEP) are concurrently acquired during steady state visual stimulation, at 8 Hz, with a b/w "windmill" pattern, in nine human subjects. The pattern contrast is varied (1%, 10%, 100%) according to a stimulation protocol.ResultsIn this study, we present the measuring system; the results consist in concurrent recordings of hemodynamic changes and evoked potential responses emerging from different contrast levels of a patterned stimulus.The concentration of [HbO2] increases and [HHb] decreases after the onset of the stimulus. Their variation shows a clear relationship with the contrast value: large contrast produce huge difference in concentration, while low contrast provokes small concentration difference. This behaviour is similar to the already known relationship between VEP response amplitude and contrast.ConclusionThe simultaneous recording and analysis of NIRS and VEP signals in humans during visual stimulation with a b/w pattern at variable contrast, demonstrates a strong linear correlation between hemodynamic changes and evoked potential amplitude. Furthermore both responses present a logarithmic profile with stimulus contrast

    Measuring Dynamics of Scattering Centers in the Ocular Fundus

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    The study is focused on the analysis of the diffusing-wave-spectroscopy signalrecorded invivo on the ocular fundus of a rabbit eye. The motion of the scattered sites wasmeasured as a function of the pressure exerted by a Goldmann contact lens and during themoderate temperature increase induced by a therapeutic laser diode. Temporal fluctuations ofthe signal revel motion of molecules and thus changes in tissues temperature andchorioretinal blood velocity. Experimental results show the ability of the system to detectmotion of the scattering sites in the ocular fundus layers during variations of the ocularpressure and laser heating

    In-vivo diffusing-wave-spectroscopy measurements of the ocular fundus

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    We present what is to our knowledge the first observation of a diffusing-wave-spectroscopy signal recorded in-vivo on the ocular fundus. A modified ophthalmic microscope was developed which can acquire diffusing-wave-spectroscopy signal from the eye fundus. The diffusing-wave-spectroscopy signal was recorded in-vivo on a rabbit eye during transpupillary thermotherapy. Experimental results show the ability of the system to detect motion of the scattering sites in the ocular fundus layers during laser thermal heating. (c) 2007 Optical Society of America

    Reciprocal interference between the NRF2 and LPS signaling pathways on the immune-metabolic phenotype of peritoneal macrophages

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    The metabolic and immune adaptation to extracellular signals allows macrophages to carry out specialized functions involved in immune protection and tissue homeostasis. Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that coordinates cell redox and metabolic responses to stressors. However, the individual and concomitant activation of NRF2 and inflammatory pathways have been poorly investigated in isolated macrophages. We here took advantage of reporter mice for the transcriptional activities of NRF2 and nuclear factor-kB (NF\u3baB), a key transcription factor in inflammation, and observe a persisting reciprocal interference in the response of peritoneal macrophages to the respective activators, tert-Butylhydroquinone (tBHQ) and lipopolysaccharide (LPS). When analyzed separately by gene expression studies, these pathways trigger macrophage-specific metabolic and proliferative target genes that are associated with tBHQ-induced pentose phosphate pathway (PPP) with no proliferative response, and with opposite effects observed with LPS. Importantly, the simultaneous administration of tBHQ + LPS alters the effects of each individual pathway in a target gene-specific manner. In fact, this co-treatment potentiates the effects of tBHQ on the antioxidant enzyme, HMOX1, and the antibacterial enzyme, IRG1, respectively; moreover, the combined treatment reduces tBHQ activity on the glycolytic enzymes, TALDO1 and TKT, and decreases LPS effects on the metabolic enzyme IDH1, the proliferation-related proteins KI67 and PPAT, and the inflammatory cytokines IL-1\u3b2, IL-6, and TNF\u3b1. Altogether, our results show that the activation of NRF2 redirects the metabolic, immune, and proliferative response of peritoneal macrophages to inflammatory signals, with relevant consequences for the pharmacological treatment of diseases that are associated with unopposed inflammatory responses

    An IoT Measurement System Based on LoRaWAN for Additive Manufacturing

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    The Industrial Internet of Things (IIoT) paradigm represents a significant leap forward for sensor networks, potentially enabling wide-area and innovative measurement systems. In this scenario, smart sensors might be equipped with novel low-power and long range communication technologies to realize a so-called low-power wide-area network (LPWAN). One of the most popular representative cases is the LoRaWAN (Long Range WAN) network, where nodes are based on the widespread LoRa physical layer, generally optimized to minimize energy consumption, while guaranteeing long-range coverage and low-cost deployment. Additive manufacturing is a further pillar of the IIoT paradigm, and advanced measurement capabilities may be required to monitor significant parameters during the production of artifacts, as well as to evaluate environmental indicators in the deployment site. To this end, this study addresses some specific LoRa-based smart sensors embedded within artifacts during the early stage of the production phase, as well as their behavior once they have been deployed in the final location. An experimental evaluation was carried out considering two different LoRa end-nodes, namely, the Microchip RN2483 LoRa Mote and the Tinovi PM-IO-5-SM LoRaWAN IO Module. The final goal of this research was to assess the effectiveness of the LoRa-based sensor network design, both in terms of suitability for the aforementioned application and, specifically, in terms of energy consumption and long-range operation capabilities. Energy optimization, battery life prediction, and connectivity range evaluation are key aspects in this application context, since, once the sensors are embedded into artifacts, they will no longer be accessible

    Comparison of VLP-16 and MRS-1000 LiDAR systems with absolute interferometer

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    Nowadays, LiDARs hold a relevant place in providing the environmental sensing required by most ADAS. Promoted by such increasing demand, many new manufacturers are emerging and, new LiDARs are continuously made available on the market. If, on the one hand, the availability of LiDARs with increasing performance and reducing cost has brought significant benefits also promoting the spread of such measuring systems in other areas such as industrial controls and agriculture, on the other, it has made it more difficult to extricate in the immense set of LiDARs present on the market today. In response to this growing need for standards and methods capable of comparing the various LiDARs, many international standards and scientific publications are being produced on the subject. In this paper, we continue our work on LiDARs characterization, focusing our attention on comparing the performances of two of the must popular systems - namely, the MRS 1000 by Sick and the VLP 16 by Velodyne. Starting from the analysis of the warm-up time and stability, such a comparison focused on analyzing the axial error of both systems. Such errors have been estimated by exploiting a custom rail system and an absolute interferometer. The obtained results revealed warm-up times of a few tens of minutes and maximum absolute axial errors of a few centimeters in the range [1.5,21] m

    Driver Drowsiness Detection: A Machine Learning Approach on Skin Conductance

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    The majority of car accidents worldwide are caused by drowsy drivers. Therefore, it is important to be able to detect when a driver is starting to feel drowsy in order to warn them before a serious accident occurs. Sometimes, drivers are not aware of their own drowsiness, but changes in their body signals can indicate that they are getting tired. Previous studies have used large and intrusive sensor systems that can be worn by the driver or placed in the vehicle to collect information about the driver’s physical status from a variety of signals that are either physiological or vehicle-related. This study focuses on the use of a single wrist device that is comfortable for the driver to wear and appropriate signal processing to detect drowsiness by analyzing only the physiological skin conductance (SC) signal. To determine whether the driver is drowsy, the study tests three ensemble algorithms and finds that the Boosting algorithm is the most effective in detecting drowsiness with an accuracy of 89.4%. The results of this study show that it is possible to identify when a driver is drowsy using only signals from the skin on the wrist, and this encourages further research to develop a real-time warning system for early detection of drowsiness

    LiDARs detected signal and Target distance estimation: measurement errors from Target reflectance and multiple echos

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    The use of LiDARs in automotive is increasingly widespread. In order to operate in a critical environment such as that of mobility, these systems must offer increasingly high performance. In particular, the ability to estimate the position of objects regardless of their reflectance and presence of diffusing backgrounds is a very sought-after feature by manufacturers. In commercial systems various strategies are used to make the measurement as insensitive as possible to these effects, however, it is not possible to fully compensate for the measurement errors caused by them. In this paper, we propose two simple experimental setups to verify the presence of these measurement errors in two scenarios. Moreover, we report the performance of a commercial LiDAR (MRS 6000 by Sick) using certified reflectance standards (Spectralon (R) Diffuse Reflectance Standards, by Labsphere). For this LiDAR, the results obtained show that a logarithmic variation of the reflectance of the target of 1.26-log at a target distance 2.4 m provides incompatible measurements. Furthermore, the presence of a background at a distance shorter than 11 cm, 12 cm and 13 cm respectively with 50 %, 75 % and 99 % reflectance also provides incompatible measurements for a target distance of 1.3 m from the LiDAR
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