26,504 research outputs found
Arctic marine climate of the early nineteenth century
The climate of the early nineteenth century is likely to have been significantly cooler than that of today, as it was a period of low solar activity (the Dalton minimum) and followed a series of large volcanic eruptions. Proxy reconstructions of the temperature of the period do not agree well on the size of the temperature change, so other observational records from the period are particularly valuable. Weather observations have been extracted from the reports of the noted whaling captain William Scoresby Jr., and from the records of a series of Royal Navy expeditions to the Arctic, preserved in the UK National Archives. They demonstrate that marine climate in 1810 - 1825 was marked by consistently cold summers, with abundant sea-ice. But although the period was significantly colder than the modern average, there was considerable variability: in the Greenland Sea the summers following the Tambora eruption (1816 and 1817) were noticeably warmer, and had less sea-ice coverage, than the years immediately preceding them; and the sea-ice coverage in Lancaster Sound in 1819 and 1820 was low even by modern standards. © 2010 Author(s)
Passivation of Si nanocrystals in SiO[sub 2]: Atomic versus molecular hydrogen
Photoluminescence measurements were used to investigate the effect of atomic and molecular hydrogen on the passivation of Si nanocrystals in SiO₂. Significant increases in the luminescence intensity and lifetime were found in samples coated with a thin Al layer prior to a standard anneal in molecular hydrogen. This is shown to be consistent with enhanced passivation of the nanocrystals by atomic hydrogen.The authors acknowledge financial support from the
Australian Research Council
BARTER:promoting local spending behavior
In the wake of the 2008 economic collapse, there is renewed interest in strategies for ensuring the future economic success of nations in a globalized marketplace. One of the main ideas being championed by governments is to promote growth by encouraging local spending, although it is not clear how to motivate this behavioral shift. Local currency initiatives are increasingly popular, though due to certain practicalities are rarely successful in fostering long term and widespread change in spending behaviors. We report on the development of a persuasive system (BARTER) that leverages mobile and ubiquitous technology to overcome some of the limitations of local currencies, while also providing users with the insight needed to determine for themselves how local spending may benet their community
Matrix Degradation in Human Immunodeficiency Virus Type 1-Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study.
Background: Extensive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in HIV-associated TB. Methods: We performed a cross-sectional study of matrix turnover in HIV type 1 (HIV-1)-infected and -uninfected TB patients and controls, and a prospective cohort study of HIV-1-infected TB patients at risk of TB immune reconstitution inflammatory syndrome (TB-IRIS), in Cape Town, South Africa. Sputum and plasma MMP concentrations were quantified by Luminex, plasma procollagen III N-terminal propeptide (PIIINP) by enzyme-linked immunosorbent assay, and urinary lipoarabinomannan (LAM) by Alere Determine TB LAM assay. Peripheral blood mononuclear cells from healthy donors were cultured with Mycobacterium tuberculosis and extracellular matrix in a 3D model of TB granuloma formation. Results: MMP activity differed between HIV-1-infected and -uninfected TB patients and corresponded with specific TB clinical phenotypes. HIV-1-infected TB patients had reduced pulmonary MMP concentrations, associated with reduced cavitation, but increased plasma PIIINP, compared to HIV-1-uninfected TB patients. Elevated extrapulmonary extracellular matrix turnover was associated with TB-IRIS, both before and during TB-IRIS onset. The predominant collagenase was MMP-8, which was likely neutrophil derived and M. tuberculosis-antigen driven. Mycobacterium tuberculosis-induced matrix degradation was suppressed by the MMP inhibitor doxycycline in vitro. Conclusions: MMP activity in TB differs by HIV-1 status and compartment, and releases matrix degradation products. Matrix turnover in HIV-1-infected patients is increased before and during TB-IRIS, informing novel diagnostic strategies. MMP inhibition is a potential host-directed therapy strategy for prevention and treatment of TB-IRIS
A model for alignment between microscopic rods and vorticity
Numerical simulations show that microscopic rod-like bodies suspended in a
turbulent flow tend to align with the vorticity vector, rather than with the
dominant eignevector of the strain-rate tensor. This paper investigates an
analytically solvable limit of a model for alignment in a random velocity field
with isotropic statistics. The vorticity varies very slowly and the isotropic
random flow is equivalent to a pure strain with statistics which are
axisymmetric about the direction of the vorticity. We analyse the alignment in
a weakly fluctuating uniaxial strain field, as a function of the product of the
strain relaxation time and the angular velocity about
the vorticity axis. We find that when , the rods are
predominantly either perpendicular or parallel to the vorticity
Office buildings and the environment : the increasing role of facility managers
The Australian commercial stock emits 12% of all greenhouse gas emissions however the commercial property market has some inherent barriers to sustainability (DSE, 2005). A substantial proportion of the stock is owned by institutional investors who are unconvinced by the need to improve their stock and pass on running costs to tenants (Callender & Key, 1997). The links between the built environment and sustainability issues such as fossil fuel consumption and climate change is clear. In developed countries buildings contribute around half of all carbon dioxide emissions and offer considerable scope for a significant contribution to sustainability through ecologically aware design and increased energy efficiency (BRE, 1996). As capital values are not greatly affected by sustainability, owners react by doing little or nothing and the effect is to limit sustainability-related investment and undermine efforts to deliver sustainability in the sector. Facility managers are in an influential position to help address sustainability issues via an increased awareness of energy efficiency and CO2 emissions.Even though the efficiency of buildings is primarily focused on new stock, with an existing churn replacement rate of approximately 2-3% the existing stock must be improved if urban built environment greenhouse gas emissions are to be reduced – clearly the management of existing stock must therefore contribute to substantial savings in energy use. Much of the property and surveying research has previously adopted an illustrative case study approach advocating the benefits of ESD and energy efficiency in existing buildings. This research adopts a radically different approach and profiles the entire office stock of a global CBD, namely Melbourne, which is seeking to become a carbon neutral city by 2020 (City of Melbourne, 2003). The research also employs scenario forecasting to model future changes to the stock over a fifteen year period. This paper sets out the rationale for the research and establishes the methodological approach adopted by the research team. The results provides a unique insight into the variations between different building types and grades of office buildings, which in turn will allow facility managers to gain a better understanding of where gains in energy efficiency can be made.<br /
The kink Casimir energy in a lattice sine-Gordon model
The Casimir energy of quantum fluctuations about the classical kink
configuration is computed numerically for a recently proposed lattice
sine-Gordon model. This energy depends periodically on the kink position and is
found to be approximately sinusoidal.Comment: 10 pages, 4 postscript figure
Expression and regulation of Cek-8, a cell to cell signalling receptor in developing chick limb buds
The structural and behaviourial barriers to sustainable real estate development
Sustainable real estate development appears, on literal translation of both terms, to be an oxymoron - however it is a concept that the real estate profession needs to embrace knowledgably. On one hand it can be argued that real estate development is required for continued economic growth and the adoption of sustainability measures is required to mitigate climate change and global warming. Over the last few years there has been growth in the number of sustainability tools available to designers and operators of buildings. For example, in the US the LEED scheme enables designers to assess the environmental impact of their design and to benchmark the sustainability of the design against industry recognised criteria. LEED follows a similar format to the UK’s Building Research Establishment Environmental Assessment Method (BREEAM) introduced in 1990 and the Australian ‘GreenStar’ introduced in 2004. Even though there are an increasing number of sustainability tools available to designers, it still remains that the degree of uptake of the tools has been sporadic. This paper discusses the barriers to sustainable real estate development. Firstly it identifies the barriers to uptake and secondly it establishes the structural barriers in the market which prevent the wider uptake of tools.<br /
- …