31,226 research outputs found

    Short turn-around intercontinental clock synchronization using very-long-baseline interferometry

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    During the past year work was accomplished to bring into regular operation a VLBI system for making intercontinental clock comparisons with a turn around of a few days from the time of data taking. Earlier VLBI systems required several weeks to produce results. The present system, which is not yet complete, incorporates a number of refinements not available in earlier systems, such as dual frequency inosopheric delay cancellation and wider synthesized bandwidths with instrumental phase calibration

    Cytokine gene polymorphisms in preterm infants with necrotising enterocolitis: genetic association study

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    BACKGROUND The inflammatory cytokine cascade is implicated in the pathogenesis of necrotising enterocolitis (NEC). Genetic association studies of cytokine polymorphisms may help to detect molecular mechanisms that are causally related to the disease process. AIM To examine associations between the common genetic variants in candidate inflammatory cytokine genes and NEC in preterm infants. METHODS Multi-centre case-control and genetic association study. DNA samples were collected from 50 preterm infants with NEC and 50 controls matched for gestational age and ethnic group recruited to a multi-centre case-control study. Ten candidate single-nucleotide polymorphisms in cytokines previously associated with infectious or inflammatory diseases were genotyped. The findings were included in random-effects meta-analyses with data from previous genetic association studies. RESULTS All allele distributions were in Hardy-Weinberg equilibrium. None of the studied cytokine polymorphisms was significantly associated with NEC. Four previous genetic association studies of cytokine polymorphisms and NEC in preterm infants were found. Meta-analyses were possible for several single-nucleotide polymorphisms. These increased the precision of the estimates of effect size but did not reveal any significant associations. CONCLUSIONS The available data are not consistent with more than modest associations between these candidate cytokine variant alleles and NEC in preterm infants. Data from future association studies of these polymorphisms may be added to the meta-analyses to obtain more precise estimates of effects sizes.The study was funded by Tenovus (Scotland)

    Earth orbital teleoperator systems evaluation

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    The mechanical extension of the human operator to remote and specialized environments poses a series of complex operational questions. A technical and scientific team was organized to investigate these questions through conducting specific laboratory and analytical studies. The intent of the studies was to determine the human operator requirements for remotely manned systems and to determine the particular effects that various system parameters have on human operator performance. In so doing, certain design criteria based on empirically derived data concerning the ultimate control system, the human operator, were added to the Teleoperator Development Program

    The H1 Forward Track Detector at HERA II

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    In order to maintain efficient tracking in the forward region of H1 after the luminosity upgrade of the HERA machine, the H1 Forward Track Detector was also upgraded. While much of the original software and techniques used for the HERA I phase could be reused, the software for pattern recognition was completely rewritten. This, along with several other improvements in hit finding and high-level track reconstruction, are described in detail together with a summary of the performance of the detector.Comment: Minor revision requested by journal (JINST) edito

    Developing mathematical thinking in the primary classroom: liberating students and teachers as learners of mathematics

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    This paper reports on a research study conducted with a group of practising primary school teachers (n = 24) in North East Scotland during 2011–2012. The teachers were all participants in a newly developed Masters course that had been designed with the aim of promoting the development of mathematical thinking in the primary classroom as part of project supported by the Scottish Government. The paper presents the background for this initiative within the context of the Scottish Curriculum for Excellence reform. Particular attention is given to the epistemological positioning of the researchers as this influenced both the curriculum design process and also the theoretical framing of the research study which are both described. The project was set up within a design research framework, which aimed to promote classroom-based action research on the part of participants through the course and also research by the university researchers into the process of curriculum development. The research questions focused on the teachers’ confidence, competence, attitudes and beliefs in relation to mathematics and their expectations and experiences of the impact on pupil learning arising from this course. Empirical data were drawn from pre- and post-course surveys, interviews and observations of the discussion forums in the online environment. Findings from this study highlight the way the course had a transformational and emancipatory impact on these teachers. They also highlight ways in which the ‘framing’ of particular aspects of the curriculum had an oppressive impact on learners in the ways that suppressed creativity and limited the exercise of learner autonomy. Furthermore, they highlight the ways in which a number of these teachers had experienced mathematics as a school subject in very negative ways, involving high levels of ‘symbolic violence’ and of being ‘labelled’

    What Do All These Numbers Mean? Data Visualization as an Innovative Methodology to Make Program Decisions

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    Background: There is a lack of consistent, comprehensible data collection and analysis methods for evaluating teacher preparation program’s coverage of required standards for accreditation. Of particular concern is the adequate coverage of standards and competencies that address the teaching of English learners and teachers of students from culturally and linguistically diverse backgrounds. Purpose: To graphically convey the findings of a faculty survey regarding English learner and multicultural content in teacher preparation coursework in order to inform them of inadequate coverage (and saturation) of those particular teaching standards and competencies. Setting: A small teacher preparation program in a Northern California public university that prepares elementary school teachers and special education teachers. Intervention: 10 full and part-time faculty members in a teacher preparation program that prepares elementary and special education teachers. Research Design: Congruency study, in which raw data from faculty survey responses were compared with rated program responses to teacher preparation standards by means of a relational database with graphing output capabilities. Data Collection: A survey instrument was designed and administered to all faculty members in the program. Findings: The resulting radar maps and other graphic outputs allowed faculty to clearly see where their course content aligned with the program accreditation response and where more coverage of that particular competency was necessary. Conclusions: The use of relational databases was a highly effective method for helping one teacher preparation program to visualize their progress towards meeting standards for teacher preparation in the area of student diversity and the teaching of English learners. Keywords: data visualization, program evaluation, teacher developmen

    Colloidal Electrostatic Interactions Near a Conducting Surface

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    Charge-stabilized colloidal spheres dispersed in deionized water are supposed to repel each other. Instead, artifact-corrected video microscopy measurements reveal an anomalous long-ranged like-charge attraction in the interparticle pair potential when the spheres are confined to a layer by even a single charged glass surface. These attractions can be masked by electrostatic repulsions at low ionic strengths. Coating the bounding surfaces with a conducting gold layer suppresses the attraction. These observations suggest a possible mechanism for confinement-induced attractions.Comment: 4 pages, 2 figure

    Witness for initial system-environment correlations in open system dynamics

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    We study the evolution of a general open quantum system when the system and its environment are initially correlated. We show that the trace distance between two states of the open system can increase above its initial value, and derive tight upper bounds for the growth of the distinguishability of open system states. This represents a generalization of the contraction property of quantum dynamical maps. The obtained inequalities can be interpreted in terms of the exchange of information between the system and the environment, and lead to a witness for system-environment correlations which can be determined through measurements on the open system alone.Comment: 4 pages, 1 figur
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