Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Mitochondrial decline in ageing robs cells of ATP. However, animal studies show that long wavelength exposure (650-900 nm) over weeks partially restores ATP and improves function. The likely mechanism is via long wavelengths reducing nanoscopic interfacial water viscosity around ATP rota pumps, improving their efficiency. Recently, repeated 670 nm exposures have been used on the aged human retina, which has high-energy demands and significant mitochondrial and functional decline, to improve vision. We show here that single 3 min 670 nm exposures, at much lower energies than previously used, are sufficient to significantly improve for 1 week cone mediated colour contrast thresholds (detection) in ageing populations (37-70 years) to levels associated with younger subjects. But light needs to be delivered at specific times. In environments with artificial lighting humans are rarely dark-adapted, hence cone function becomes critical. This intervention, demonstrated to improve aged mitochondrial function can be applied to enhance colour vision in old age

Singular measures in circle dynamics

Critical circle homeomorphisms have an invariant measure totally singular with respect to the Lebesgue measure. We prove that singularities of the invariant measure are of Holder type. The Hausdorff dimension of the invariant measure is less than 1 but greater than 0

Improved planning abilities in binge eating.

OBJECTIVE: The role of planning in binge eating episodes is unknown. We investigated the characteristics of planning associated with food cues in binging patients. We studied planning based on backward reasoning, reasoning that determines a sequence of actions back to front from the final outcome. METHOD: A cross-sectional study was conducted with 20 healthy participants, 20 bulimia nervosa (BN), 22 restrictive (ANR) and 23 binging anorexia nervosa (ANB), without any concomitant impulsive disorder. In neutral/relaxing, binge food and stressful conditions, backward reasoning was assessed with the Race game, promotion of delayed large rewards with an intertemporal discounting task, attention with the Simon task, and repeating a dominant behavior with the Go/No-go task. RESULTS: BN and to a lower extent ANB patients succeeded more at the Race game in food than in neutral condition. This difference discriminated binging from non-binging participants. Backward reasoning in the food condition was associated with lower approach behavior toward food in BN patients, and higher food avoidance in ANB patients. Enhanced backward reasoning in the food condition related to preferences for delayed large rewards in BN patients. In BN and ANB patients the enhanced success rate at the Race game in the food condition was associated with higher attention paid to binge food. CONCLUSION: These findings introduce a novel process underlying binges: planning based on backward reasoning is associated with binges. It likely aims to reduce craving for binge foods and extend binge refractory period in BN patients, and avoid binging in ANB patients. Shifts between these goals might explain shifts between eating disorder subtypes

Exact 1/N and Optimized Perturbative Evaluation of mu_c for Homogeneous Interacting Bose Gases

In the framework of the O(N) three-dimensional effective scalar field model for homogeneous dilute weakly interacting Bose gases we use the 1/N expansion to evaluate, within the large N limit, the parameter r_c which is directly related to the critical chemical potential mu_c. This quantity enters the order-a^2 n^{2/3} coefficient contributing to the critical temperature shift Delta T_c where a represents the s-wave scattering length and n represents the density. Compared to the recent precise numerical lattice simulation results, our calculation suggests that the large N approximation performs rather well even for the physical case N=2. We then calculate the same quantity but using different forms of the optimized perturbative (variational) method, showing that these produce excellent results both for the finite N and large-N cases.Comment: 12 pages, 2 figures. We have performed a refined and extended numerical analysis to take into account the very recent results of Ref. [15

The Fokker-Planck equation for bistable potential in the optimized expansion

The optimized expansion is used to formulate a systematic approximation scheme to the probability distribution of a stochastic system. The first order approximation for the one-dimensional system driven by noise in an anharmonic potential is shown to agree well with the exact solution of the Fokker-Planck equation. Even for a bistable system the whole period of evolution to equilibrium is correctly described at various noise intensities.Comment: 12 pages, LATEX, 3 Postscript figures compressed an

Challenges in Bridging Social Semantics and Formal Semantics on the Web

This paper describes several results of Wimmics, a research lab which names stands for: web-instrumented man-machine interactions, communities, and semantics. The approaches introduced here rely on graph-oriented knowledge representation, reasoning and operationalization to model and support actors, actions and interactions in web-based epistemic communities. The re-search results are applied to support and foster interactions in online communities and manage their resources

The Possibility of Reconciling Quantum Mechanics with Classical Probability Theory

We describe a scheme for constructing quantum mechanics in which a quantum system is considered as a collection of open classical subsystems. This allows using the formal classical logic and classical probability theory in quantum mechanics. Our approach nevertheless allows completely reproducing the standard mathematical formalism of quantum mechanics and identifying its applicability limits. We especially attend to the quantum state reduction problem.Comment: Latex, 14 pages, 1 figur

String Organization of Field Theories: Duality and Gauge Invariance

String theories should reduce to ordinary four-dimensional field theories at low energies. Yet the formulation of the two are so different that such a connection, if it exists, is not immediately obvious. With the Schwinger proper-time representation, and the spinor helicity technique, it has been shown that field theories can indeed be written in a string-like manner, thus resulting in simplifications in practical calculations, and providing novel insights into gauge and gravitational theories. This paper continues the study of string organization of field theories by focusing on the question of local duality. It is shown that a single expression for the sum of many diagrams can indeed be written for QED, thereby simulating the duality property in strings. The relation between a single diagram and the dual sum is somewhat analogous to the relation between a old- fashioned perturbation diagram and a Feynman diagram. Dual expressions are particularly significant for gauge theories because they are gauge invariant while expressions for single diagrams are not.Comment: 20 pages in Latex, including seven figures in postscrip