High Temperature Oxidized SnO 2

Undoped and Sb-doped tin oxide films were prepared by d.c. reactive ion sputtering in an argon atmosphere with oxygen partial pressures ranging from 0 to 50%. The films were anneled in oxygen in the temperature range 360 - 893℃. The effect of thermal annealing on the changes in electrical and structural properties is described

Exotic Smoothness and Quantum Gravity

Since the first work on exotic smoothness in physics, it was folklore to assume a direct influence of exotic smoothness to quantum gravity. Thus, the negative result of Duston (arXiv:0911.4068) was a surprise. A closer look into the semi-classical approach uncovered the implicit assumption of a close connection between geometry and smoothness structure. But both structures, geometry and smoothness, are independent of each other. In this paper we calculate the "smoothness structure" part of the path integral in quantum gravity assuming that the "sum over geometries" is already given. For that purpose we use the knot surgery of Fintushel and Stern applied to the class E(n) of elliptic surfaces. We mainly focus our attention to the K3 surfaces E(2). Then we assume that every exotic smoothness structure of the K3 surface can be generated by knot or link surgery a la Fintushel and Stern. The results are applied to the calculation of expectation values. Here we discuss the two observables, volume and Wilson loop, for the construction of an exotic 4-manifold using the knot $5_{2}$ and the Whitehead link $Wh$. By using Mostow rigidity, we obtain a topological contribution to the expectation value of the volume. Furthermore we obtain a justification of area quantization.Comment: 16 pages, 1 Figure, 1 Table subm. Class. Quant. Grav

The application of whole-body vibration in physiotherapy – A narrative review

Whole-body vibration (WBV) training is a very popular kind of practice in sport, fitness and physiotherapy. This work reviews the current knowledge regarding the use and effectiveness of WBV in the physiotherapy. The discrepancies between different authors’ results are probably due to divergence in WBV training protocols. The paperwork clearly showed that despite its ultimate effects, exercises on a vibration platform are safe, feasible, and well tolerated by patients with different disorders. This narrative review should help physiotherapists verify therapy programs regarding patients’ exposure to WBV

Studies of the magnetic axis switching in magnetite

The influence of the external magnetic field on magnetic and crystallographic structure of magnetite was studied. We have confirmed, by means of vibrating sample magnetometer measurements, that external magnetic field can switch the easy magnetic axis to the new crystallographic direction. We have also proved by the direct observation of the crystalline structure that this phenomenon is strictly related to the crystallographic structure relaxation

Ditto: Towards Decentralised Similarity Search for Web3 Services

The Web has become an integral part of life, and over the past decade, it has become increasingly centralised, leading to a number of challenges such as censorship and control, particularly in search engines. Recently, the paradigm of the decentralised Web (DWeb), or Web3, has emerged, which aims to provide decentralised alternatives to current systems with decentralised control, transparency, and openness. In this paper we introduce Ditto, a decentralised search mechanism for DWeb content, based on similarity search. Ditto uses locality sensitive hashing (LSH) to extract similarity signatures and records from content, which are stored on a decentralised index on top of a distributed hash table (DHT). Ditto uniquely supports numerous underlying content networks and types, and supports various use-cases, including keyword-search. Our evaluation shows that our system is feasible and that our search quality, delay, and overhead are comparable to those currently accepted by users of DWeb and search systems

A Survey on Content Retrieval on the Decentralised Web

The control, governance, and management of the web have become increasingly centralised, resulting in security, privacy, and censorship concerns. Decentralised initiatives have emerged to address these issues, beginning with decentralised file systems. These systems have gained popularity, with major platforms serving millions of content requests daily. Complementing the file systems are decentralised search engines and name registry infrastructures, together forming the basis of a decentralised web. This survey paper analyses research trends and emerging technologies for content retrieval on the decentralised web, encompassing both academic literature and industrial projects. Several challenges hinder the realisation of a fully decentralised web. Achieving comparable performance to centralised systems without compromising decentralisation is a key challenge. Hybrid infrastructures, blending centralised components with verifiability mechanisms, show promise to improve decentralised initiatives. While decentralised file systems have seen more mature deployments, they still face challenges such as usability, performance, privacy, and content moderation. Integrating these systems with decentralised name-registries offers a potential for improved usability with human-readable and persistent names for content. Further research is needed to address security concerns in decentralised name-registries and enhance governance and crypto-economic incentive mechanisms

Density of Gr1-positive myeloid precursor cells, p-STAT3 expression and gene expression pattern in canine mammary cancer metastasis

The very recent studies on human and mice models have indicated an important role of myeloid precursor cells (progenitors or not fully differentiated cells that express the Gr1 antigen also called Gr1-positive myeloid suppressor cells) in the tumor progression and metastasis. They are thought to suppress the immune system and promote angiogenesis via Signal transducer and activator of transcription 3 (STAT3) activation. As of now there is no data available on the correlation of Gr1-positive cell number, phosphorylated STAT3 (p-STAT3) expression and cancer ability to metastasis. Thus, we counted the myeloid precursor cell number and analyzed p-STAT3 expression in 50 canine mammary tumors that gave local/distant metastases and did not metastasize. We showed that the number of Gr1-positive cells and p-STAT3 expression are significantly higher (p < 0.001) in the metastatic tumors than in the non-metastatic ones. We also observed higher expression of p-STAT3 in the canine mammary cancer cell lines with metastatic potential than in other cell lines (p < 0.001). Moreover, the number of myeloid precursors and p-STAT3 expression in metastatic tumors correlate strongly. The tumor infiltrating myeloid precursor cells may invigorate the STAT3 activity (probably via vascular endothelial growth factor – VEGF) that contributes to the tumor angiogenesis and furthermore tumor`s ability to metastasize. The analysis of gene expression in canine mammary cancer cell lines with metastatic potential indicated that semaphorin 3B (SEMA3B) and neuropilin receptors (NRP) may also be important elements in this process. Thus, we discuss the possible interactions within the tumor that may be required for cancer metastatis

Photoperiodic regulation in a wild-derived mouse strain

MSM/Ms (MSM) is a mouse strain derived from Japanese wild mice, Mus musculus molossinus, that maintains the ability to synthesize melatonin in patterns reflecting the ambient photoperiod. The objective of this study was to characterize the effects of photoperiodic variation on metabolic and reproductive traits, and the related changes in pituitary–hypothalamic gene expression in MSM mice. MSM mice were kept in long (LP) or short photoperiod (SP) for 6 weeks. Our results demonstrate that MSM mice kept in LP, as compared with mice kept in SP, display higher expression of genes encoding thyrotropin (TSH) in the pars tuberalis, thyroid hormone deiodinase 2 (dio2) in the tanycytes and RFamide-related peptide (RFRP3) in the hypothalamus, and lower expression of dio3 in the tanycytes, along with larger body and reproductive organ mass. Additionally, to assess the effects of the gestational photoperiodic environment on the expression of these genes, we kept MSM mice in LP or SP from gestation and studied their offspring. We show that the gestational photoperiod affects the TSH/dio pathway in newborn MSM mice in a similar way to adults. This result indicates a transgenerational effect of photoperiod from the mother to the fetus in utero. Overall, these results indicate that photoperiod can influence neuroendocrine regulation in a melatonin-proficient mouse strain, in a manner similar to that documented in other seasonal rodent species. MSM mice may therefore become a useful model for research into the molecular basis of photoperiodic regulation of seasonal biology