5,659 research outputs found
Unmet need, epistemic injustice and early death: how social policy for Autistic adults in England and Wales fails to slay Beveridgeâs Five Giants
Listeria Monocytogenes: a rare cause of endophthalmitis, a case report.
Listeria monocytogenes is a known cause of gastroenteritis. Invasive disease can follow bacteremia causing meningoencephalitis, endocarditis and spontaneous miscarriages in immunocompromised patients and pregnant women respectively. We present the first case in England of endogenous endophthalmitis caused by L. monocytogenes following acute gastroenteritis in an immunocompetent host. A 50-year-old South Asian female presented with acute painful unilateral visual loss occurring shortly after an episode of self-limiting gastroenteritis. On examination, the eye was very inflamed with a hypopyon uveitis. A vitreous biopsy confirmed growth of L.monocytogenes serotype 1/2a. Diagnostic delay commonly occurs in endogenous endophthalmitis and exacerbates an already poor visual prognosis. Listeria spp. must be considered in ocular inflammation following gastroenteritis. The intraocular inflammation subsided but surgical intervention was required to remove vitreous debris and improve visual acuity
Late Light Curves of Normal Type Ia Supernovae
We present late-epoch optical photometry (BVRI) of seven
normal/super-luminous Type Ia supernovae: SN 2000E, SN 2000ce, SN 2000cx, SN
2001C, SN 2001V, SN 2001bg, SN 2001dp. The photometry of these objects was
obtained using a template subtraction method to eliminate galaxy light
contamination during aperture photometry. We show the optical light curves of
these supernovae out to epochs of up to ~640 days after the explosion of the
supernova. We show a linear decline in these data during the epoch of 200-500
days after explosion with the decline rate in the B,V,& R bands equal to about
1.4 mag/100 days, but the decline rate of the I-band is much shallower at 0.94
mag/100 days.Comment: 33 pages, 11 figures, Accepted for publication in The Astronomical
Journa
Growth, Body Composition, and Lung Function in Prepubertal Children with Cystic Fibrosis Diagnosed by Newborn Screening
Background:
Children with cystic fibrosis (CF) are at risk of altered body composition (BC). Newborn screening (NBS) may lead to improved BC outcomes. We investigated BC and its relationship with lung function in prepubertal children diagnosed with CF by NBS. Secondary aims explored predictors of fatâfree mass (FFM) and lung function. /
Methods:
Thirtyâseven screened (nonâmeconium ileus) children with CF (20 boys) born 2007â2012 had a dualâenergy xâray absorptiometry scan at 5â8 years to determine wholeâbody (WB) and appendicular BC. Anthropometry was performed and routine spirometry recorded. Results were converted to zâscores, heightâadjusted (fat mass index [FMI] and FFM index [FFMI]) and compared with population mean values. Predictors of forced expiratory volume in 1 second (FEV1) were assessed using linear regression. /
Results:
Height, body mass index (BMI), and FEV1 were within normal limits, however, weight and BC were significantly low compared with reference data (weight, P = .03; WB FMI, P = .001; WB FFMI, P = .009). Gender differences were detected, with lower appendicular BC in boys and lower weight, BMI, and BC in girls. The association between FEV1 and WB FFMI (r = 0.38; P = .02) was stronger than with BMI (r = 0.29; P = .08). WB FFMI was the only significant predictor of FEV1 in a multivariable model (95% CI, 0.11â0.99; P = .016). /
Conclusion:
In this NBS CF population, gender differences in growth and BC were apparent despite preserved lung function. These results support BC assessment in prepubertal children, particularly girls, with an opportunity to direct interventions to optimize FFM
Late Light Curves of Normally-Luminous Type Ia Supernovae
The use of Type Ia supernovae as cosmological tools has reinforced the need
to better understand these objects and their light curves. The light curves of
Type Ia supernovae are powered by the nuclear decay of . The late time light curves can provide insight into the behavior of
the decay products and their effect of the shape of the curves. We present the
optical light curves of six "normal" Type Ia supernovae, obtained at late times
with template image subtraction, and the fits of these light curves to
supernova energy deposition models.Comment: Proceedings of Astronomy with Radioactivities V Conferenc
Are inner disc misalignments common? ALMA reveals an isotropic outer disc inclination distribution for young dipper stars
Dippers are a common class of young variable star exhibiting day-long dimmings with depths of up to several tens of perâcent. A standard explanation is that dippers host nearly edge-on (id â 70°) protoplanetary discs that allow close-in (10 au) disc resolved by ALMA and that inner disc misalignments may be common during the protoplanetary phase. More than one mechanism may contribute to the dipper phenomenon, including accretion-driven warps and âbrokenâ discs caused by inclined (sub-)stellar or planetary companions
Flame propagation in random media
We introduce a phase-field model to describe the dynamics of a
self-sustaining propagating combustion front within a medium of randomly
distributed reactants. Numerical simulations of this model show that a flame
front exists for reactant concentration , while its vanishing at
is consistent with mean-field percolation theory. For , we find
that the interface associated with the diffuse combustion zone exhibits kinetic
roughening characteristic of the Kardar-Parisi-Zhang equation.Comment: 4, LR541
SN2013fs and SN2013fr: Exploring the circumstellar-material diversity in Type II supernovae
We present photometry and spectroscopy of SN2013fs and SN2013fr in the first
100 days post-explosion. Both objects showed transient, relatively narrow
H emission lines characteristic of SNeIIn, but later resembled normal
SNeII-P or SNeII-L, indicative of fleeting interaction with circumstellar
material (CSM). SN2013fs was discovered within 8hr of explosion. Its light
curve exhibits a plateau, with spectra revealing strong CSM interaction at
early times. It is a less luminous version of the transitional SNIIn PTF11iqb,
further demonstrating a continuum of CSM interaction intensity between SNeII-P
and IIn. It requires dense CSM within 6.510~cm of the
progenitor, from a phase of advanced pre-SN mass loss shortly before explosion.
Spectropolarimetry of SN2013fs shows little continuum polarization, but
noticeable line polarization during the plateau phase. SN2013fr morphed from a
SNIIn at early times to a SNII-L. After the first epoch its narrow lines
probably arose from host-galaxy emission, but the bright, narrow H
emission at early times may be intrinsic. As for SN2013fs, this would point to
a short-lived phase of strong CSM interaction if proven to be intrinsic,
suggesting a continuum between SNeIIn and II-L. It is a low-velocity SNII-L,
like SN2009kr but more luminous. SN2013fr also developed an IR excess at later
times, due to warm CSM dust that require a more sustained phase of strong
pre-SN mass loss.Comment: MNRAS accepted. 28 pages, 23 figures, 8 table
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