339 research outputs found
Towards new background independent representations for Loop Quantum Gravity
Recently, uniqueness theorems were constructed for the representation used in
Loop Quantum Gravity. We explore the existence of alternate representations by
weakening the assumptions of the so called LOST uniqueness theorem. The
weakened assumptions seem physically reasonable and retain the key requirement
of explicit background independence. For simplicity, we restrict attention to
the case of gauge group U(1).Comment: 22 pages, minor change
Feasibility of intraventricular administration of etoposide in patients with metastatic brain tumours
As the systemic administration of etoposide is effective in the treatment of relapsed and metastatic brain tumours, a pilot trial was designed to study the feasibility of intraventricular administration of etoposide in such patients. 14 patients aged 2.1 to 33.2 years were treated with intraventricular etoposide simultaneously with either oral or intravenous chemotherapy with trofosfamide or carboplatin and etoposide. In 59 courses (1–12/patient) 0.5 mg etoposide was administered daily via an indwelling subcutaneous reservoir for 5 consecutive days every 2–5 weeks over a period of 0–11 months. During 15 courses in 5 patients serial CSF samples were obtained and etoposide levels were determined by reversed-phase HPLC. Side effects included transient headache and bacterial meningitis, each during 2 courses. Pharmacokinetic data analysis in the CSF (11 courses, 4 patients) revealed a terminal half-life of 7.4±1.2 hours and an AUC of 25.0 ± 9.5 μg h ml–1(mean ± standard deviation). The volume of distribution at steady state and total clearance exhibited a large interindividual variability with mean values of 0.16 l and 0.46 ml min–1respectively. Intraventricularly administered etoposide is well tolerated. CSF peak levels exceed more than 100-fold those achieved with intravenous infusions. Further studies should be focused on optimizing the dose and schedule and on determining the effectiveness of intraventricularly administered etoposide. © 2001 Cancer Research Campaign http://www.bjcancer.co
Stratification of the orbit space in gauge theories. The role of nongeneric strata
Gauge theory is a theory with constraints and, for that reason, the space of
physical states is not a manifold but a stratified space (orbifold) with
singularities. The classification of strata for smooth (and generalized)
connections is reviewed as well as the formulation of the physical space as the
zero set of a momentum map. Several important features of nongeneric strata are
discussed and new results are presented suggesting an important role for these
strata as concentrators of the measure in ground state functionals and as a
source of multiple structures in low-lying excitations.Comment: 22 pages Latex, 1 figur
The Early Universe in Loop Quantum Cosmology
Loop quantum cosmology applies techniques derived for a background
independent quantization of general relativity to cosmological situations and
draws conclusions for the very early universe. Direct implications for the
singularity problem as well as phenomenology in the context of inflation or
bouncing universes result, which will be reviewed here. The discussion focuses
on recent new results for structure formation and generalizations of the
methods.Comment: 10 pages, 3 figures, plenary talk at VI Mexican School on Gravitation
and Mathematical Physics, Nov 21-27, 200
Properties of the Volume Operator in Loop Quantum Gravity I: Results
We analyze the spectral properties of the volume operator of Ashtekar and
Lewandowski in Loop Quantum Gravity, which is the quantum analogue of the
classical volume expression for regions in three dimensional Riemannian space.
Our analysis considers for the first time generic graph vertices of valence
greater than four. Here we find that the geometry of the underlying vertex
characterizes the spectral properties of the volume operator, in particular the
presence of a `volume gap' (a smallest non-zero eigenvalue in the spectrum) is
found to depend on the vertex embedding. We compute the set of all
non-spatially diffeomorphic non-coplanar vertex embeddings for vertices of
valence 5--7, and argue that these sets can be used to label spatial
diffeomorphism invariant states. We observe how gauge invariance connects
vertex geometry and representation properties of the underlying gauge group in
a natural way. Analytical results on the spectrum on 4-valent vertices are
included, for which the presence of a volume gap is proved. This paper presents
our main results; details are provided by a companion paper arXiv:0706.0382v1.Comment: 36 pages, 7 figures, LaTeX. See also companion paper
arXiv:0706.0382v1. Version as published in CQG in 2008. See arXiv:1003.2348
for important remarks regarding the sigma configurations. Subsequent
computations have revealed some minor errors, which do not change the
qualitative results but modify some of the numbers presented her
On the Relation between Operator Constraint --, Master Constraint --, Reduced Phase Space --, and Path Integral Quantisation
Path integral formulations for gauge theories must start from the canonical
formulation in order to obtain the correct measure. A possible avenue to derive
it is to start from the reduced phase space formulation. In this article we
review this rather involved procedure in full generality. Moreover, we
demonstrate that the reduced phase space path integral formulation formally
agrees with the Dirac's operator constraint quantisation and, more
specifically, with the Master constraint quantisation for first class
constraints. For first class constraints with non trivial structure functions
the equivalence can only be established by passing to Abelian(ised) constraints
which is always possible locally in phase space. Generically, the correct
configuration space path integral measure deviates from the exponential of the
Lagrangian action. The corrections are especially severe if the theory suffers
from second class secondary constraints. In a companion paper we compute these
corrections for the Holst and Plebanski formulations of GR on which current
spin foam models are based.Comment: 43 page
Loop Quantum Gravity a la Aharonov-Bohm
The state space of Loop Quantum Gravity admits a decomposition into
orthogonal subspaces associated to diffeomorphism equivalence classes of
spin-network graphs. In this paper I investigate the possibility of obtaining
this state space from the quantization of a topological field theory with many
degrees of freedom. The starting point is a 3-manifold with a network of
defect-lines. A locally-flat connection on this manifold can have non-trivial
holonomy around non-contractible loops. This is in fact the mathematical origin
of the Aharonov-Bohm effect. I quantize this theory using standard field
theoretical methods. The functional integral defining the scalar product is
shown to reduce to a finite dimensional integral over moduli space. A
non-trivial measure given by the Faddeev-Popov determinant is derived. I argue
that the scalar product obtained coincides with the one used in Loop Quantum
Gravity. I provide an explicit derivation in the case of a single defect-line,
corresponding to a single loop in Loop Quantum Gravity. Moreover, I discuss the
relation with spin-networks as used in the context of spin foam models.Comment: 19 pages, 1 figure; v2: corrected typos, section 4 expanded
Oriented Matroids -- Combinatorial Structures Underlying Loop Quantum Gravity
We analyze combinatorial structures which play a central role in determining
spectral properties of the volume operator in loop quantum gravity (LQG). These
structures encode geometrical information of the embedding of arbitrary valence
vertices of a graph in 3-dimensional Riemannian space, and can be represented
by sign strings containing relative orientations of embedded edges. We
demonstrate that these signature factors are a special representation of the
general mathematical concept of an oriented matroid. Moreover, we show that
oriented matroids can also be used to describe the topology (connectedness) of
directed graphs. Hence the mathematical methods developed for oriented matroids
can be applied to the difficult combinatorics of embedded graphs underlying the
construction of LQG. As a first application we revisit the analysis of [4-5],
and find that enumeration of all possible sign configurations used there is
equivalent to enumerating all realizable oriented matroids of rank 3, and thus
can be greatly simplified. We find that for 7-valent vertices having no
coplanar triples of edge tangents, the smallest non-zero eigenvalue of the
volume spectrum does not grow as one increases the maximum spin \jmax at the
vertex, for any orientation of the edge tangents. This indicates that, in
contrast to the area operator, considering large \jmax does not necessarily
imply large volume eigenvalues. In addition we give an outlook to possible
starting points for rewriting the combinatorics of LQG in terms of oriented
matroids.Comment: 43 pages, 26 figures, LaTeX. Version published in CQG. Typos
corrected, presentation slightly extende
Discovery of very-high-energy emission from RGB J2243+203 and derivation of its redshift upper limit
Very-high-energy (VHE; 100 GeV) gamma-ray emission from the blazar RGB
J2243+203 was discovered with the VERITAS Cherenkov telescope array, during the
period between 21 and 24 December 2014. The VERITAS energy spectrum from this
source can be fit by a power law with a photon index of , and a
flux normalization at 0.15 TeV of . The integrated
\textit{Fermi}-LAT flux from 1 GeV to 100 GeV during the VERITAS detection is
, which is an order of
magnitude larger than the four-year-averaged flux in the same energy range
reported in the 3FGL catalog, (). The detection with VERITAS
triggered observations in the X-ray band with the \textit{Swift}-XRT. However,
due to scheduling constraints \textit{Swift}-XRT observations were performed 67
hours after the VERITAS detection, not simultaneous with the VERITAS
observations. The observed X-ray energy spectrum between 2 keV and 10 keV can
be fitted with a power-law with a spectral index of , and the
integrated photon flux in the same energy band is . EBL model-dependent upper limits
of the blazar redshift have been derived. Depending on the EBL model used, the
upper limit varies in the range from z to z
Spherically Symmetric Quantum Geometry: Hamiltonian Constraint
Variables adapted to the quantum dynamics of spherically symmetric models are
introduced, which further simplify the spherically symmetric volume operator
and allow an explicit computation of all matrix elements of the Euclidean and
Lorentzian Hamiltonian constraints. The construction fits completely into the
general scheme available in loop quantum gravity for the quantization of the
full theory as well as symmetric models. This then presents a further
consistency check of the whole scheme in inhomogeneous situations, lending
further credence to the physical results obtained so far mainly in homogeneous
models. New applications in particular of the spherically symmetric model in
the context of black hole physics are discussed.Comment: 33 page
- …