Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β-Cyclodextrin Derivatives

β-cyclodextrin (βCyD) derivatives equipped with aromatic appendages at the secondary face exhibit tailorable self-assembling capabilities. The aromatic modules can participate in inclusion phenomena and/or aromatic-aromatic interactions. Supramolecular species can thus form that, at their turn, can engage in further co-assembling with third components in a highly regulated manner; the design of nonviral gene delivery systems is an illustrative example. Endowing such systems with stimuli responsiveness while keeping diastereomeric purity and a low synthetic effort is a highly wanted advancement. Here, we show that an azobenzene moiety can be “clicked” to a single secondary O-2 position of βCyD affording 1,2,3-triazole-linked βCyD-azobenzene derivatives that undergo reversible light-controlled self-organization into dimers where the monomer components face their secondary rims. Their photoswitching and supramolecular properties have been thoroughly characterized by UV-vis absorption, induced circular dichroism, nuclear magnetic resonance, and computational techniques. As model processes, the formation of inclusion complexes between a water-soluble triazolylazobenzene derivative and βCyD as well as the assembly of native βCyD/βCyD-azobenzene derivative heterodimers have been investigated in parallel. The stability of the host-guest supramolecules has been challenged against the competitor guest adamantylamine and the decrease of the medium polarity using methanol-water mixtures. The collective data support that the E-configured βCyD-azobenzene derivatives, in aqueous solution, form dimers stabilized by the interplay of aromatic-aromatic and aromatic-βCyD cavity interactions after partial reciprocal inclusion. Photoswitching to the Z-isomer disrupts the dimers into monomeric species, offering opportunity for the spatiotemporal control of the organizational status by light.Ministerio de Ciencia e Innovación PID2019-105858RB-I00, PID2020-118403GB-I00, PID2020-118384GB-I00, PID2020-119130GB-I00Fondo Europeo de Desarrollo Regional PID2021-124247OB-C21Junta de Andalucía P20_00166, US-1380698, P12-FQM-1467Universidad de Sevilla FPU18/02922, FPU19/0436

Spanish Research Report for 2018.

Spanish catch and effort information used in this Report is based on the preliminary logbook data contributed by the Spanish Administration. The logbooks information for 2018 was available haul by haul. Table 1 presents the preliminary Spanish catches by species and Division in 2018 in NAFO Regulatory Area. Total effort of the Spanish fleet in 2018 was 1,082 fishing days. In 2018, IEO scientific observers were on board 279 fishing days that it means 26 % of the Spanish total effort. All length, age and biological information presented in this paper is based on sampling carried out by IEO scientific observers. In 2018, 425 samples were taken with 44,499 individuals of different species examined (Table 2)

BROMATOLOGICAL ANALYSIS OF ANNATTO (Bixa orellana L.) SEEDS

The objective of this study was to carry out a bromatological and physicochemical analysis of local annatto seeds and a commercial pasteObjective: to carry out a bromatological and physicochemical analysis of local annatto seeds and a commercialpaste.Materials and Methods: local annatto seeds to which a physicochemical analysis was carried out whereash, humidity (weight difference), dry matter, proteins were determined. ADF and NDF, fat, and in addition,bromatological analysis was carried out on the samples and the commercial pasta.Results: sample M3 (dark heart-shaped annatto without filaments) presented the highest values. The bixincontent was recorded with 4.09% in sample M2 (heart-shaped red annatto without filaments) and thecommercial paste was the lowest with 0.56%.Limitations and Implications of the study: the importance of performing the bromatological and physicalchemicalanalysis of annatto seeds of local genotypes determined which of the local samples and the commercialpaste are the ones that contain the greatest amount of bixin.Findings and Conclusions: Sample M3 (dark heart-shaped annatto without filaments) presented the highestvalues. The highest bixin content was found in the smooth heart-red variety and the lowest value in thecommercial pasta

Spanish Research Report for 2017

Spanish catch and effort information used in this Report is based on the logbook data contributed by the Spanish Administration. The logbooks information for 2017 was available haul by haul. Table 1 presents the Spanish catches by species and Division in 2017 in NAFO Regulatory Area. Total effort of the Spanish fleet in 2017 was 1,037 fishing days. In 2017, IEO scientific observers were on board 329 fishing days that it means 32 % of the Spanish total effort. All length, age and biological information presented in this paper is based on sampling carried out by IEO scientific observers. In 2017, 483 samples were taken with 57,988 individuals of different species examined (Table 2)

Spanish Research Report for 2019

Spanish catch and effort information used in this Report is based on the preliminary logbook data contributed by the Spanish Administration. The logbooks information for 2019 was available haul by haul. Table 1 presents the preliminary Spanish catches by species and Division in 2019 in NAFO Regulatory Area. Total effort of the Spanish fleet in 2019 was 1,272 fishing days. In 2019, IEO scientific observers were on board 257 fishing days that it means 20 % of the Spanish total effort. All length, age and biological information presented in this paper is based on sampling carried out by IEO scientific observers. In 2019, 376 samples were taken with 45,831 individuals of different species examined (Table 2)

Spanish Research Report for 2015

Spanish catch information used in this Report is based on the logbook data contributed by the Spanish Administration. Table 1 presents the catches by species and Division in 2015 based on this information. The split of catches and effort between the different gears in this Report are based on information from NAFO observers on board. In 2015 NAFO observers information from 1,272 days was available while total effort of the Spanish fleet in NAFO Regulatory Area was 1,317 days (around 97% coverage). In addition to NAFO observers, IEO scientific observers were on board 320 fishing days that it means 24 % of the Spanish total effort. All length, age and biological information presented in this paper is based on sampling carried out by IEO scientific observers: 576 samples were taken in 2015, with 59,883 individuals of different species examined (Table 2).Postprint0,000

Observation of two excited Bc+ states and measurement of the Bc+ (2S) mass in pp collisions at √s = 13 TeV

CMS Collaboration: et al.Signals consistent with the Bc+(2S) and Bc∗+(2S) states are observed in proton-proton collisions at √s = 13 TeV, in an event sample corresponding to an integrated luminosity of 143 fb-1, collected by the CMS experiment during the 2015-2018 LHC running periods. These excited bc states are observed in the Bc+π+π- invariant mass spectrum, with the ground state Bc+ reconstructed through its decay to J/ψπ+. The two states are reconstructed as two well-resolved peaks, separated in mass by 29.1±1.5(stat)±0.7(syst) MeV. The observation of two peaks, rather than one, is established with a significance exceeding five standard deviations. The mass of the Bc+(2S) meson is measured to be 6871.0±1.2(stat)±0.8(syst)±0.8(Bc+) MeV, where the last term corresponds to the uncertainty in the world-average Bc+ mass

Search for supersymmetry in proton-proton collisions at 13 TeV in final states with jets and missing transverse momentum

Results are reported from a search for supersymmetric particles in the final state with multiple jets and large missing transverse momentum. The search uses a sample of proton-proton collisions at s = 13 TeV collected with the CMS detector in 2016–2018, corresponding to an integrated luminosity of 137 fb, representing essentially the full LHC Run 2 data sample. The analysis is performed in a four-dimensional search region defined in terms of the number of jets, the number of tagged bottom quark jets, the scalar sum of jet transverse momenta, and the magnitude of the vector sum of jet transverse momenta. No significant excess in the event yield is observed relative to the expected background contributions from standard model processes. Limits on the pair production of gluinos and squarks are obtained in the framework of simplified models for supersymmetric particle production and decay processes. Assuming the lightest supersymmetric particle to be a neutralino, lower limits on the gluino mass as large as 2000 to 2310 GeV are obtained at 95% confidence level, while lower limits on the squark mass as large as 1190 to 1630 GeV are obtained, depending on the production scenario.Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract No. 675440 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the “Excellence of Science — EOS” — be.h project n. 30820817; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Lendület (“Momentum”) Program and the J´anos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850 and 125105 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia María de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Welch Foundation, contract C-1845; and the Weston Havens Foundation (U.S.A.)

Observation of single top quark production in association with a Z Boson in proton-proton collisions at √s =13 TeV

CMS Collaboration: et al.The observation of single top quark production in association with a Z boson and a quark (tZq) is reported. Events from proton-proton collisions at a center-of-mass energy of 13 TeV containing three charged leptons (either electrons or muons) and at least two jets are analyzed. The data were collected with the CMS detector in 2016 and 2017 and correspond to an integrated luminosity of 77.4fb-1. The increased integrated luminosity, a multivariate lepton identification, and a redesigned analysis strategy improve significantly the sensitivity of the analysis compared to previous searches for tZq production. The tZq signal is observed with a significance well over 5 standard deviations. The measured tZq production cross section is σ(pp→tZq→t?+?-q)=111±13(stat)-9+11(syst) fb, for dilepton invariant masses above 30 GeV, in agreement with the standard model expectation

Search for a W' boson decaying to a τ lepton and a neutrino in proton-proton collisions at s=13TeV

A search for a new high-mass resonance decaying to a τlepton and a neutrino is reported. The analysis uses proton-proton collision data collected by the CMS experiment at the LHC at √s=13 TeV, corresponding to an integrated luminosity of 35.9 fb−1. The search utilizes hadronically decaying τleptons. No excess in the event yield is observed at high transverse masses of the τand missing transverse momentum. An interpretation of results within the sequential standard model excludes W′boson masses below 4.0 TeV at 95% confidence level. Existing limits are also improved on models in which the W′boson decays preferentially to fermions of the third generation. Heavy W′bosons with masses less than 1.7–3.9 TeV, depending on the coupling in the non-universal G(221) model, are excluded at 95% confidence level. These are the most stringent limits on this model to dateIndividuals have received support from the Marie-Curie programme and the European Research Council and Horizon 2020 Grant, contract No. 675440 (European Union); the Leventis Foundation; the Alfred P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the “Excellence of Science - EOS” - be.h project n. 30820817; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Lendület (“Momentum”) Programme and the János Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program ÚNKP, the NKFIA research grants 123842, 123959, 124845, 124850 and 125105 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS programme of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus programme of the Ministry of Science and Higher Education, the National Science Centre (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia María de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programmes cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Welch Foundation, contract C-1845; and the Weston Havens Foundation (USA)