Perceived Damage by Elk in the Arkansas Ozarks

Wildlife managers in Arkansas are faced with managing a growing population of Rocky Mountain elk (Cervus elaphus neloni) that has extended its range to incorporate private lands near the Buffalo National River (BNR) in northcentral Arkansas. This range expansion has created conflicts between private landowners and wildlife management personnel. To document the extent of damage and assess attitudes of landowners with elk on their land, interviews were conducted with landowners who contacted us or the Arkansas Game and Fish Commission about problems with elk. A survey also was created and sent to landowners who live near the BNR in Boone and Newton counties and who may have elk on their land. Ten of 18 respondents with elk on their land reported having a problem with nuisance activity. Landowners indicated that most damage was to pastures, hay crops, and food plots. Damage appeared to occur more often in summer, when elk home ranges were smallest, than in other seasons. Landowners incurring damage from elk had a strong negative opinion. Continued research into effective management practices should be conducted to properly manage this growing population of elk and reduce conflicts between elk and Arkansas landowners

The shell structure and chamber production cycle of the cephalopod Spirula (Coleoidea, Decabrachia)

The endocochleate coleoid cephalopod Spirula spirula, the only present-day representative of the order Spirulida, secretes a coiled shell consisting of a series of chambers divided by septa and connected by a siphuncle. It is the shell closest to those of Recent and extinct ectochleate cephalopods: nautiloids, ammonoids. Therefore, its study may help to understand which characters remained unchanged or became transformed during the evolution of endocochleates. We have carried out detailed observations on the different structures composing the Spirula shell, with the aim of reconstructing their morphology, distribution, and mutual relationships. Alongside this, we also review the previous profuse terminology. Taking into account the additional information provided by growth lines and crystal orientations, we propose mechanisms for the secretion of the shell structures. All these mechanisms are integrated in a consistent way into a general model of chamber formation. The periostracum is secreted within a distinct periostracal groove. The outer shell layer is secreted externally to the periostracum by the soft tissues lining the shell externally. The inner shell layer is produced by the shell wall mantle, whereas the septa and the siphuncle are made periodically by a differentiated septal/siphuncular mantle. The most adoral septal mantle edge changes from secreting septal to inner shell wall material to produce the mural flap. The adapical ridge is formed by passive precipitates from cameral fluid residues trapped by surface tension, whereas the fibrous prismatic deposits of the connecting ring are biominerals produced remotely within mantle secretions. Homologies with Nautilus and Sepia are discussed.Projekt DEA

Arms and the mollusc: An evolutionary arms race has produced armor based on molluscan biomineralization

A.G.C. acknowledges funding from Project No. PID2020116660GB-I00, funded by Spanish Ministry of Science and Innovation (MCIN/AEI/10.13039/ 501100011033). Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature.More than half a billion years ago in the early Cambrian period, there began an evolutionary arms race between molluscs and their predators, in which molluscs developed armor in the form of a biomineral exoskeleton—a shell—to avoid being eaten by predators that were developing jaws and other novel means of devouring them. The mollusc fabricates multiple layers of shell, each of a particular microstructure of a composite between an inorganic and an organic phase, which are the end result of more than 500 million years of coevolution with increasingly deadly predators. Molluscan biomineralization is an excellent case to study how a biological process produces a complex structure, because the shell is constructed as an extracellular structure in which all construction materials are passed out of the cells to self-assemble outside the cell wall. We consider what is known of the development of multilayer composite armor in the form of nacre (mother of pearl) and the other strong microstructures with which molluscs construct their shells.MCIN/AEI/10.13039/ 501100011033 PID2020116660GB-I00CRUE-CSI

Nonlinear Dynamics of the Perceived Pitch of Complex Sounds

We apply results from nonlinear dynamics to an old problem in acoustical physics: the mechanism of the perception of the pitch of sounds, especially the sounds known as complex tones that are important for music and speech intelligibility

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function.

STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk? SUMMARY ANSWER Expression levels of PLGF, sIL-2R, endostatin and angiogenin were significantly increased by dNK cells from high-risk pregnancies, and angiogenin and endostatin were found to alter trophoblast function. WHAT IS KNOWN ALREADY During early pregnancy, maternal uterine spiral arteries are remodelled from small diameter, low-flow, high-resistance vessels into larger diameter, higher flow vessels, with low-resistance. This change is essential for the developing fetus to obtain sufficient oxygen and nutrients. dNK cells have been implicated in this process. STUDY DESIGN, SIZE, DURATION dNK cells were isolated from first trimester terminations of pregnancies (obtained with local ethical approval) screened for normal- or high-resistance index, indicative of cases least (21%) likely to have developed pre-eclampsia had the pregnancy not been terminated (n = 18 each group). Secreted factors and the effects of these on the trophoblast cell line, SGHPL-4, were assessed in vitro. PARTICIPANTS/MATERIALS, SETTING, METHODS A multiplex assay was used to assess dNK cell-secreted factors. SGHPL-4 cell functions were assessed using time-lapse microscopy, 3D invasion assays, endothelial-like tube formation ability and western blot analysis. MAIN RESULTS AND THE ROLE OF CHANCE The expression levels of PLGF (P < 0.01), sIL-2R (P < 0.01), endostatin (P < 0.05) and angiogenin (P < 0.05) were significantly increased by dNK cells from high-risk pregnancies. Endostatin significantly decreased SGHPL-4 invasion (P < 0.05), SGHPL-4 tube formation (P < 0.05) and SGHPL-4 Aktser473 phosphorylation (P < 0.05). Angiogenin significantly decreased SGHPL-4 invasion (P < 0.05), but increased SGHPL-4 tube formation (P < 0.01) and decreased SGHPL-4 Aktser473 phosphorylation (P < 0.05). LIMITATIONS, REASONS FOR CAUTION The culture of dNK cells and protein concentrations in vitro may not fully represent the in vivo situation. Although SGHPL-4 cells are extravillous trophoblast derived, further studies would be needed to confirm the roles of angiogenin and endostatin in vivo. WIDER IMPLICATIONS OF THE FINDINGS The altered expression of secreted factors of dNK cells may contribute to pregnancy disorders associated with poor spiral artery remodelling. STUDY FUNDING/COMPETING INTEREST(S) This study was supported by the Wellcome Trust (project reference 091550). R.F. was a recipient of a PhD studentship from the Division of Biomedical Sciences, St. George's, University of London. The authors have no conflict of interests

Crystal growth as an excitable medium

Crystal growth has been widely studied for many years, and, since the pioneering work of Burton, Cabrera and Frank, spirals and target patterns on the crystal surface have been understood as forms of tangential crystal growth mediated by defects and by two-dimensional nucleation. Similar spirals and target patterns are ubiquitous in physical systems describable as excitable media. Here, we demonstrate that this is not merely a superficial resemblance, that the physics of crystal growth can be set within the framework of an excitable medium, and that appreciating this correspondence may prove useful to both fields. Apart from solid crystals, we discuss how our model applies to the biomaterial nacre, formed by layer growth of a biological liquid crystal

CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXXIX. THE ANEMIA OF INFECTION. STUDIES ON THE IRON-BINDING CAPACITY OF SERUM 1

It has been generally recognized since Barkan&apos;s original observations in 1929 (1) that the iron in serum is non-dialyzable and non-ultrafilterable at pH 7.3 and, therefore, is probably protein-bound (2-4). To which of the serum proteins the iron is bound was not clearly established until recently. Earlier work indicated that half-saturation with ammonium sulfate precipitated serum iron quantitatively together with the globulins (5). Vahlquist (4) with the aid of the electrophoretic technique concluded that the iron in serum is bound to both albumin and globulin, the a and ,3 globulins serving as the principal carriers. Following their demonstration of a protein component in raw egg white capable of binding iron (6), Schade and Caroline investigated various fractions of human plasma prepared by E. J. Cohn and his associates for a similar property (7) and discovered that, qualitatively, Fraction IV-3, 4 was active in this respect, as shown by biological and colorimetric tests. lin is 90,000, the iron content of the iron-protein complex is 0.125 per cent. Studies over a wide range of pH have revealed that at neutral pH the iron is non-dialyzable whereas at pH 5 the iron becomes dialyzable

Triggering synchronized oscillations through arbitrarily weak diversity in close-to-threshold excitable media

It is shown that arbitrarily weak (frozen) heterogeneity can induce global synchronized oscillations in excitable media close to threshold. The work is carried out on networks of coupled van der Pol-FitzHugh-Nagumo oscillators. The result is shown to be robust against the presence of internal dynamical noise.Comment: 4 pages (RevTeX 3 style), 5 EPS figures, submitted to Phys. Rev. E (16 aug 2001