179 research outputs found

    Compression and intelligence: social environments and communication

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    Compression has been advocated as one of the principles which pervades inductive inference and prediction - and, from there, it has also been recurrent in definitions and tests of intelligence. However, this connection is less explicit in new approaches to intelligence. In this paper, we advocate that the notion of compression can appear again in definitions and tests of intelligence through the concepts of `mind-reading¿ and `communication¿ in the context of multi-agent systems and social environments. Our main position is that two-part Minimum Message Length (MML) compression is not only more natural and effective for agents with limited resources, but it is also much more appropriate for agents in (co-operative) social environments than one-part compression schemes - particularly those using a posterior-weighted mixture of all available models following Solomonoff¿s theory of prediction. We think that the realisation of these differences is important to avoid a naive view of `intelligence as compression¿ in favour of a better understanding of how, why and where (one-part or two-part, lossless or lossy) compression is needed.We thank the anonymous reviewers for their helpful comments, and we thank Kurt Kleiner for some challenging and ultimately very helpful questions in the broad area of this work. We also acknowledge the funding from the Spanish MEC and MICINN for projects TIN2009-06078-E/TIN, Consolider-Ingenio CSD2007-00022 and TIN2010-21062-C02, and Generalitat Valenciana for Prometeo/2008/051.Dowe, DL.; Hernández Orallo, J.; Das, PK. (2011). Compression and intelligence: social environments and communication. En Artificial General Intelligence. Springer Verlag (Germany). 6830:204-211. https://doi.org/10.1007/978-3-642-22887-2_21S2042116830Chaitin, G.J.: Godel’s theorem and information. 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Conf. on Computational Intelligence & multimedia applications (ICCIMA 1998), Gippsland, Australia, pp. 101–106 (February 1998)Hernández-Orallo, J.: Beyond the Turing Test. J. Logic, Language & Information 9(4), 447–466 (2000)Hernández-Orallo, J.: Constructive reinforcement learning. International Journal of Intelligent Systems 15(3), 241–264 (2000)Hernández-Orallo, J.: On the computational measurement of intelligence factors. In: Meystel, A. (ed.) Performance metrics for intelligent systems workshop, pp. 1–8. National Institute of Standards and Technology, Gaithersburg, MD, U.S.A (2000)Hernández-Orallo, J., Dowe, D.L.: Measuring universal intelligence: Towards an anytime intelligence test. Artificial Intelligence 174(18), 1508–1539 (2010)Hernández-Orallo, J., Minaya-Collado, N.: A formal definition of intelligence based on an intensional variant of Kolmogorov complexity. In: Proc. Intl Symposium of Engineering of Intelligent Systems (EIS 1998), pp. 146–163. ICSC Press (1998)Legg, S., Hutter, M.: Universal intelligence: A definition of machine intelligence. Minds and Machines 17(4), 391–444 (2007)Lewis, D.K., Shelby-Richardson, J.: Scriven on human unpredictability. Philosophical Studies: An International Journal for Philosophy in the Analytic Tradition 17(5), 69–74 (1966)Oppy, G., Dowe, D.L.: The Turing Test. In: Zalta, E.N. (ed.) Stanford Encyclopedia of Philosophy, Stanford University, Stanford (2011), http://plato.stanford.edu/entries/turing-test/Salomon, D., Motta, G., Bryant, D.C.O.N.: Handbook of data compression. Springer-Verlag New York Inc., Heidelberg (2009)Sanghi, P., Dowe, D.L.: A computer program capable of passing I.Q. tests. In: 4th International Conference on Cognitive Science (and 7th Australasian Society for Cognitive Science Conference), vol. 2, pp. 570–575. Univ. of NSW, Sydney, Australia (July 2003)Sayood, K.: Introduction to data compression. 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    Feasibility Study of an Electrodialysis System for In-Home Water Desalination and Purification in Urban India

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    Desalination of high salinity water is an effective way of improving the aesthetic quality of drinking water and has been demonstrated to be a characteristic valued by consumers. Across India, 60% of the groundwater, the primary water source for millions, is brackish or contains a high salt content with total dissolved solids (TDS) ranging from 500 parts per million (ppm) to 3,000ppm. The government does not provide sufficient desalination treatment before the water reaches the tap of a consumer. Therefore consumers have turned to in-home desalination. However, current products are either expensive or have low recovery, product water output per untreated feed water, (∼30%) wasting water resources. Electrodialysis (ED) is a promising technology that desalinates water while maintaining higher recovery (up to 95%) compared to existing consumer reverse osmosis (RO) products. This paper first explores the in-home desalination market to determine critical design requirements for an in-home ED system. A model was then used to evaluate and optimize the performance of an ED stack at this scale and designated salinity range. Additionally, testing was conducted in order to validate the model and demonstrate feasibility. Finally, cost estimates of the proposed in-home ED system and product design concept are presented. The results of this work identified a system design that provides consumers with up to 80% recovery of feed water with cost and size competitive to currently available in-home RO products

    A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases

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    In high-grade serous ovarian cancer (HGSOC), higher densities of both B cells and the CD8 + T-cell infiltrate were associated with a better prognosis. However, the precise role of B cells in the antitumor response remains unknown. As peritoneal metastases are often responsible for relapse, our aim was to characterize the role of B cells in the antitumor immune response in HGSOC metastases. Unmatched pre and post-chemotherapy HGSOC metastases were studied. B-cell localization was assessed by immunostaining. Their cytokines and chemokines were measured by a multiplex assay, and their phenotype was assessed by flow cytometry. Further in vitro and in vivo assays highlighted the role of B cells and plasma cell IgGs in the development of cytotoxic responses and dendritic cell activation. B cells mainly infiltrated lymphoid structures in the stroma of HGSOC metastases. There was a strong B-cell memory response directed at a restricted repertoire of antigens and production of tumor-specific IgGs by plasma cells. These responses were enhanced by chemotherapy. Interestingly, transcript levels of CD20 correlated with markers of immune cytolytic responses and immune complexes with tumor-derived IgGs stimulated the expression of the costimulatory molecule CD86 on antigen-presenting cells. A positive role for B cells in the antitumor response was also supported by B-cell depletion in a syngeneic mouse model of peritoneal metastasis. Our data showed that B cells infiltrating HGSOC omental metastases support the development of an antitumor response. Clin Cancer Res; 1-13. ©2016 AACR

    Multivariate analysis as a tool for selecting the vine pruning pretreatment towards the highest enzymatic hydrolysis yield

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    Lignocellulosic materials require pretreatment to remove lignin enabling the enzyme access to the cellulose. This work used multivariate analysis to investigate the acid and alkali pretreatments of vine pruning followed by enzymatic hydrolysis. The best acid pretreatment conditions were H2SO4 1.5%, 120 °C for 30 min, removing 68.7% of hemicellulose, enabling 95.8% of cellulose recovery. However, this treatment was not enough to allow the enzyme hydrolysis. A second step of treatment with NaOH 3.0% at 120 °C without agitation for 60 min led to a material with 75.0% of cellulose and 25.0% of lignin. However, the lowest glucose yield (80.86% and 32.26 g L?1 of glucose) was obtained after the enzyme hydrolysis of this material. The highest glucose yield (98.72% with 35.06 g L?1) was obtained using a pretreated material containing 68.1% of cellulose and 31.9% of lignin obtained after a milder condition (NaOH 2% at 100 °C), thus showing that not all the lignin need to be removed to obtain a high saccharification yield. A less severe pretreatment with no adverse effect on the glucose yield with the advantage of preserving the non-cellulose biomass fractions was effective for vine prune valorization.This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit, BioTecNorte operation (NORTE-01-0145-FEDER000004), the projects Multibiorefinery (POCI-01-0145-FEDER-016403), FoSynBio (POCI-01-0145-FEDER-029549) and Lignozymes (POCI-01- 0145-FEDER-029773) funded by the European Regional Development Fund under the scope of Norte 2020. In Brazil, this study was funded in part by the Coordenaçao ~ de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) - Finance Code 001, Conselho Nacional de Desenvolvimento Científico e Tecnologico (CNPq) and Fundaçao Cearense de Apoio ao Desenvolvimento Científico e Tecnologico (FUNCAP). The authors would like to acknowledge the Central Analytical (Physical Department) of Federal University of Ceara for conducting the SEM analysis and the Centro de Tecnologia Canavieira – CTC/Brazil for the support. E. Gudina and L. Rodrigues acknowledge FCT for the Post-doctoral (CEB-BPD/01/2015/07) and sabbatical (SFRH/BSAB/142991/2019) grants, respectively.info:eu-repo/semantics/publishedVersio

    Valorization, comparison and characterization of coconuts waste and cactus in a biorefinery context using NaClO2-C2H4O2 and sequential NaClO2-C2H4O2/autohydrolysis pretreatment

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    The search for new sources of lignocellulosic raw materials for the generation of energy and new compounds encourages the search for locations not well known and with a high potential for biomass availability as is the case of the Northeast Region of Brazil. Thus, the cactus (CAC), green coconut shell (GCS), mature coconut fibre and mature coconut shell were pretreated by NaClO2C2H4O2 and sequential NaClO2C2H4O2/autohydrolysis aiming at the obtention of high added-value compounds in the liquid fraction and solid phase. The yield of the solid phase was between 61.42 and 90.97% and the reduction up to 91.63% of lignin in the materials pretreated by NaClO2C2H4O2. After NaClO2C2H4O2/autohydrolysis pretreatment the obtained solids yield was between 43.57 and 52.08%, with a solubilization of the hemicellulose content up to 81.42%. For both pretreatments the cellulosic content remained almost unchanged. The pretreated solids were characterized by SEM, X-ray and crystallinity indexes showing significant modifications when submitted to pretreatments. These results were further confirmed by the enzymatic conversion yields of 81.6890.03 and 86.9790.36% of the LCMs pretreated by NaClO2C2H4O2 and pretreated by NaClO2C2H4O2/autohydrolysis, respectively. The resulting liquors had a total phenolic compounds content between 0.20 and 3.05 g/L, lignin recovered up to 7.40 g/L (absence of sulphur) and xylooligosaccharides between 16.13 and 20.37 g/L. Thus, these pretreatments showed an efficient fractionation of LCMs, especially in the GCS, being an important requirement for the generation of products and byproducts in the context of the biorefinery.The authors gratefully acknowledge the Brazilian research funding agencies CNPq and CAPES for financial support. Financial support from the Energy Sustainability Fund 2014-05 (CONACYT-SENER), Mexican Centre for Innovation in Bioenergy (CemieBio), Cluster of Bioalcohols (Ref. 249564) is gratefully acknowledged. We also gratefully acknowledge support for this research by the Mexican Science and Technology Council (CONACYT, Mexico) for the infrastructure project - INFR201601 (Ref. 269461) and CB-2015-01 (Ref. 254808).info:eu-repo/semantics/publishedVersio
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