1,043 research outputs found
Vacuum ultraviolet holography
The authors report the first demonstration of holographic techniques in the vacuum ultraviolet spectral region. Holograms were produced with coherent 1182 A radiation. The holograms were recorded in polymethyl methacrylate and read out with an electron microscope. A holographic grating with a fringe spacing of 836 A was produced and far-field Fraunhofer holograms of sub-micron particles were recorded
Laser action from a terbium beta-ketoenolate at room temperature
Laser activity is achieved in a solution of terbium tris at room temperature in a liquid solvent of acetonitrile or p-dioxane. After precipitation, the microcrystals of hydrated tris chelate are filtered, washed in distilled water, and dried. They show no signs of deterioration after storage
Doppler-Free Spectroscopy of Weak Transitions: An Analytical Model Applied to Formaldehyde
Experimental observation of Doppler-free signals for weak transitions can be
greatly facilitated by an estimate for their expected amplitudes. We derive an
analytical model which allows the Doppler-free amplitude to be estimated for
small Doppler-free signals. Application of this model to formaldehyde allows
the amplitude of experimentally observed Doppler-free signals to be reproduced
to within the experimental error.Comment: 7 pages, 7 figures, 1 table, v2: many small improvements + corrected
line assignmen
The Potential Role of Gut Microbiota in Alzheimer’s Disease: from Diagnosis to Treatment
Gut microbiota is emerging as a key regulator of many disease conditions and its dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal disorders. More recently, gut microbiome alterations have been linked to neurodegeneration through the increasingly defined gut microbiota brain axis, opening the possibility for new microbiota-based therapeutic options. Although several studies have been conducted to unravel the possible relationship between Alzheimer’s Disease (AD) pathogenesis and progression, the diagnostic and therapeutic potential of approaches aiming at restoring gut microbiota eubiosis remain to be fully addressed. In this narrative review, we briefly summarize the role of gut microbiota homeostasis in brain health and disease, and we present evidence for its dysregulation in AD patients. Based on these observations, we then discuss how dysbiosis might be exploited as a new diagnostic tool in early and advanced disease stages, and we examine the potential of prebiotics, probiotics, fecal microbiota transplantation, and diets as complementary therapeutic interventions on disease pathogenesis and progression, thus offering new insights into the diagnosis and treatment of this devastating and progressive disease
Gain without population inversion in V-type systems driven by a frequency-modulated field
We obtain gain of the probe field at multiple frequencies in a closed
three-level V-type system using frequency modulated pump field. There is no
associated population inversion among the atomic states of the probe
transition. We describe both the steady-state and transient dynamics of this
system. Under suitable conditions, the system exhibits large gain
simultaneously at series of frequencies far removed from resonance. Moreover,
the system can be tailored to exhibit multiple frequency regimes where the
probe experiences anomalous dispersion accompanied by negligible
gain-absorption over a large bandwidth, a desirable feature for obtaining
superluminal propagation of pulses with negligible distortion.Comment: 10 pages + 8 figures; To appear in Physical Review
The role of long-lived dark states in the photoluminescence dynamics of poly(phenylene vinylene) conjugated polymers. II. Excited-state quenching versus ground-state depletion
The two pulse fluorescence bleaching experiments reported in an earlier paper ͓J. Chem. Phys. 117, 454 ͑2002͔͒ are reanalyzed in the context of additional experiments. The fluorescence bleaching observed in that paper was originally ascribed to ground-state depletion. By analyzing the absorption saturation behavior and the magnitude of the pump-probe signal, we find that the absorption cross section of poly͑phenylene vinylene͒ at 400 nm is two orders of magnitude too small to significantly deplete the ground state given the pump fluences used in that experiment. Instead, the observed depletion is due to a combination of exciton-exciton annihilation at early times and dark state luminescence quenching at later times. Different experiments have different sensitivities to the fluence-dependent quenching, with time-resolved experiments like transient emission and fluorescence decay time consistently underestimating the exciton-exciton annihilation rate. Experiments that measure the integrated fluorescence, such as fluorescence saturation and bleaching, result in a consistent value for the exciton-exciton annihilation constant of 6 ϫ10 Ϫ9 cm 3 /s, while the dark state quenching constant is estimated to be at least 1.2 ϫ10 Ϫ8 cm 3 /s. Indirect evidence based on the wavelength and sample dependence of the dark state formation suggest that the dark states are charge-separated polarons. The relatively large quenching constants are consistent with what has been observed in other conjugated polymers and suggest that the long-lived dark states in particular are effective quenchers, capable of quenching thousands of surrounding chromophores
Microwave Spectroscopy of Cold Rubidium Atoms
The effect of microwave radiation on the resonance fluorescence of a cloud of
cold atoms in a magnetooptical trap is studied. The radiation
frequency was tuned near the hyperfine splitting frequency of rubidium atoms in
the 5S ground state. The microwave field induced magnetic dipole transitions
between the magnetic sublevels of the 5S(F=2) and 5S(F=3) states, resulting in
a change in the fluorescence signal. The resonance fluorescence spectra were
recorded by tuning the microwave radiation frequency. The observed spectra were
found to be substantially dependent on the transition under study and the
frequency of a repump laser used in the cooling scheme.Comment: 6 pages, 4 figure
Narrowband frequency tunable light source of continuous quadrature entanglement
We report the observation of non-classical quantum correlations of continuous
light variables from a novel type of source. It is a frequency non-degenerate
optical parametric oscillator below threshold, where signal and idler fields
are separated by 740MHz corresponding to two free spectrum ranges of the
parametric oscillator cavity. The degree of entanglement observed, - 3.8 dB, is
the highest to-date for a narrowband tunable source suitable for atomic quantum
memory and other applications in atomic physics. Finally we use the latter to
visualize the Einstein-Podolsky-Rosen paradox.Comment: 11 pages, 9 figures, LaTe
Quantum noise in the position measurement of a cavity mirror undergoing Brownian motion
We perform a quantum theoretical calculation of the noise power spectrum for
a phase measurement of the light output from a coherently driven optical cavity
with a freely moving rear mirror. We examine how the noise resulting from the
quantum back action appears among the various contributions from other noise
sources. We do not assume an ideal (homodyne) phase measurement, but rather
consider phase modulation detection, which we show has a different shot noise
level. We also take into account the effects of thermal damping of the mirror,
losses within the cavity, and classical laser noise. We relate our theoretical
results to experimental parameters, so as to make direct comparisons with
current experiments simple. We also show that in this situation, the standard
Brownian motion master equation is inadequate for describing the thermal
damping of the mirror, as it produces a spurious term in the steady-state phase
fluctuation spectrum. The corrected Brownian motion master equation [L. Diosi,
Europhys. Lett. {\bf 22}, 1 (1993)] rectifies this inadequacy.Comment: 12 pages revtex, 2 figure
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