558 research outputs found
Octonic Electrodynamics
In this paper we present eight-component values "octons", generating
associative noncommutative algebra. It is shown that the electromagnetic field
in a vacuum can be described by a generalized octonic equation, which leads
both to the wave equations for potentials and fields and to the system of
Maxwell's equations. The octonic algebra allows one to perform compact combined
calculations simultaneously with scalars, vectors, pseudoscalars and
pseudovectors. Examples of such calculations are demonstrated by deriving the
relations for energy, momentum and Lorentz invariants of the electromagnetic
field. The generalized octonic equation for electromagnetic field in a matter
is formulated.Comment: 12 pages, 1 figur
GINA - A Polarized Neutron Reflectometer at the Budapest Neutron Centre
The setup, capabilities and operation parameters of the neutron reflectometer
GINA, the recently installed "Grazing Incidence Neutron Apparatus" at the
Budapest Neutron Centre, are introduced. GINA, a dance-floor-type,
constant-energy, angle-dispersive reflectometer is equipped with a 2D
position-sensitive detector to study specular and off-specular scattering.
Wavelength options between 3.2 and 5.7 {\AA} are available for unpolarized and
polarized neutrons. Spin polarization and analysis are achieved by magnetized
transmission supermirrors and radio-frequency adiabatic spin flippers. As a
result of vertical focusing by the five-element (pyrolytic graphite)
monochromator the reflected intensity from a 20x20 mm sample has doubled. GINA
is dedicated to studies of magnetic films and heterostructures, but unpolarized
options for non-magnetic films, membranes and other surfaces are also provided.
Shortly after its startup, reflectivity values as low as 3x10-5 have been
measured on the instrument. The facility is now open for the international user
community, but its development is continuing mainly to establish new sample
environment options, the spin analysis of off-specularly scattered radiation
and further decrease of the background
The first joint ESGAR/ ESPR consensus statement on the technical performance of cross-sectional small bowel and colonic imaging
Objectives: To develop guidelines describing a standardised approach to patient preparation and acquisition protocols for magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound (US) of the small bowel and colon, with an emphasis on imaging inflammatory bowel disease. Methods: An expert consensus committee of 13 members from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) and European Society of Paediatric Radiology (ESPR) undertook a six-stage modified Delphi process, including a detailed literature review, to create a series of consensus statements concerning patient preparation, imaging hardware and image acquisition protocols. Results: One hundred and fifty-seven statements were scored for agreement by the panel of which 129 statements (82 %) achieved immediate consensus with a further 19 (12 %) achieving consensus after appropriate modification. Nine (6 %) statements were rejected as consensus could not be reached. Conclusions: These expert consensus recommendations can be used to help guide cross-sectional radiological practice for imaging the small bowel and colon. Key points: • Cross-sectional imaging is increasingly used to evaluate the bowel • Image quality is paramount to achieving high diagnostic accuracy • Guidelines concerning patient preparation and image acquisition protocols are provided
Climate change and the kidney
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality. The kidney has a unique role not only in protecting the host from heat and dehydration but also is an important site of heat-associated disease. Here we review the potential impact of global warming and heat extremes on kidney diseases. High temperatures can result in increased core temperatures, dehydration, and blood hyperosmolality. Heatstroke (both clinical and subclinical whole-body hyperthermia) may have a major role in causing both acute kidney disease, leading to increased risk of acute kidney injury from rhabdomyolysis, or heat-induced inflammatory injury to the kidney. Recurrent heat and dehydration can result in chronic kidney disease (CKD) in animals and theoretically plays a role in epidemics of CKD developing in hot regions of the world where workers are exposed to extreme heat. Heat stress and dehydration also has a role in kidney stone formation, and poor hydration habits may increase the risk for recurrent urinary tract infections. The resultant social and economic consequences include disability and loss of productivity and employment. Given the rise in world temperatures, there is a major need to better understand how heat stress can induce kidney disease, how best to provide adequate hydration, and ways to reduce the negative effects of chronic heat exposure.Published versio
Observer agreement for small bowel ultrasound in Crohn's disease: results from the METRIC trial
PURPOSE: To prospectively evaluate interobserver agreement for small bowel ultrasound (SBUS) in newly diagnosed and relapsing Crohn's disease. METHODS: A subset of patients recruited to a prospective trial comparing the diagnostic accuracy of MR enterography and SBUS underwent a second SBUS performed by one of a pool of six practitioners, who recorded the presence, activity and location of small bowel and colonic disease. Detailed segmental mural and extra-mural observations were also scored. Interobserver variability was expressed as percentage agreement with a construct reference standard, split by patient cohort, grouping disease as present or absent. Prevalence adjusted bias adjusted kappa (PABAK), and simple percentage agreement between practitioners, irrespective of the reference standard, were calculated. RESULTS: Thirty-eight patients (11 new diagnosis, 27 relapse) were recruited from two sites. Overall percentage agreement for small bowel disease presence against the consensus reference was 82% (52-95% (95%CI)), kappa coefficient (κ) 0.64, (substantial agreement) for new diagnosis and 81%, κ 0.63 (substantial agreement) for the relapsing cohort. Agreement for colonic disease presence was 64%, κ 0.27 (fair agreement) in new diagnosis and 78%,κ 0.56 (moderate agreement) in the relapsing cohort. Simple agreement between practitioners was 84% and 87% for small bowel and colonic disease presence respectively. Practitioners agreed on small bowel disease activity in 24/27 (89%) where both identified disease. Kappa agreement for detailed mural observations ranged from κ 0.00 to 1.00. CONCLUSION: There is substantial practitioner agreement for small bowel disease presence in newly diagnosed and relapsing CD patients, supporting wider dissemination of enteric US
Anomalous layering at the liquid Sn surface
X-ray reflectivity measurements on the free surface of liquid Sn are
presented. They exhibit the high-angle peak, indicative of surface-induced
layering, also found for other pure liquid metals (Hg, Ga and In). However, a
low-angle peak, not hitherto observed for any pure liquid metal, is also found,
indicating the presence of a high-density surface layer. Fluorescence and
resonant reflectivity measurements rule out the assignment of this layer to
surface-segregation of impurities. The reflectivity is modelled well by a 10%
contraction of the spacing between the first and second atomic surface layers,
relative to that of subsequent layers. Possible reasons for this are discussed.Comment: 8 pages, 9 figures; to be submitted to Phys. Rev. B; updated
references, expanded discussio
X-ray study of the electric double layer at the n-hexane/nanocolloidal silica interface
The spatial structure of the transition region between an insulator and an
electrolyte solution was studied with x-ray scattering.The electron density
profile across the n-hexane/silica sol interface (solutions with 5-nm, 7-nm,
and 12-nm colloidal particles) agrees with the theory of the electrical double
layer and shows separation of positive and negative charges. The interface
consists of three layers, i.e., a compact layer of Na+, a loose monolayer of
nanocolloidal particles as part of a thick diffuse layer, and a low-density
layer sandwiched between them. Its structure is described by a model in which
the potential gradient at the interface reflects the difference in the
potentials of "image forces" between the cationic Na+ and anionic nanoparticles
and the specific adsorption of surface charge. The density of water in the
large electric field (1-10 GV/m) of the transition region and the layering of
silica in the diffuse layer is discussed.Comment: 9 pages, 9 figure
BICEP2 II: Experiment and Three-Year Data Set
We report on the design and performance of the BICEP2 instrument and on its
three-year data set. BICEP2 was designed to measure the polarization of the
cosmic microwave background (CMB) on angular scales of 1 to 5 degrees
(=40-200), near the expected peak of the B-mode polarization signature of
primordial gravitational waves from cosmic inflation. Measuring B-modes
requires dramatic improvements in sensitivity combined with exquisite control
of systematics. The BICEP2 telescope observed from the South Pole with a 26~cm
aperture and cold, on-axis, refractive optics. BICEP2 also adopted a new
detector design in which beam-defining slot antenna arrays couple to
transition-edge sensor (TES) bolometers, all fabricated on a common substrate.
The antenna-coupled TES detectors supported scalable fabrication and
multiplexed readout that allowed BICEP2 to achieve a high detector count of 500
bolometers at 150 GHz, giving unprecedented sensitivity to B-modes at degree
angular scales. After optimization of detector and readout parameters, BICEP2
achieved an instrument noise-equivalent temperature of 15.8 K sqrt(s). The
full data set reached Stokes Q and U map depths of 87.2 nK in square-degree
pixels (5.2 K arcmin) over an effective area of 384 square degrees within
a 1000 square degree field. These are the deepest CMB polarization maps at
degree angular scales to date. The power spectrum analysis presented in a
companion paper has resulted in a significant detection of B-mode polarization
at degree scales.Comment: 30 pages, 24 figure
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