Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep

Transplacental transmission of bluetongue virus has been shown previously for the North European strain of serotype 8 (BTV-8) and for tissue culture or chicken egg-adapted vaccine strains but not for field strains of other serotypes. In this study, pregnant ewes (6 per group) were inoculated with either field or rescued strains of BTV-2 and BTV-8 in order to determine the ability of these viruses to cross the placental barrier. The field BTV-2 and BTV-8 strains was passaged once in Culicoides KC cells and once in mammalian cells. All virus inoculated sheep became infected and seroconverted against the different BTV strains used in this study. BTV RNA was detectable in the blood of all but two ewes for over 28 days but infectious virus could only be detected in the blood for a much shorter period. Interestingly, transplacental transmission of BTV-2 (both field and rescued strains) was demonstrated at high efficiency (6 out of 13 lambs born to BTV-2 infected ewes) while only 1 lamb of 12 born to BTV-8 infected ewes showed evidence of in utero infection. In addition, evidence for horizontal transmission of BTV-2 between ewes was observed. As expected, the parental BTV-2 and BTV-8 viruses and the viruses rescued by reverse genetics showed very similar properties to each other. This study showed, for the first time, that transplacental transmission of BTV-2, which had been minimally passaged in cell culture, can occur; hence such transmission might be more frequent than previously thought

Comment on "Can one predict DNA Transcription Start Sites by Studying Bubbles?"

Comment on T.S. van Erp, S. Cuesta-Lopez, J.-G. Hagmann, and M. Peyrard, Phys. Rev. Lett. 95, 218104 (2005) [arXiv: physics/0508094]

Discrete Nonlinear Schr{\"o}dinger Breathers in a Phonon Bath

We study the dynamics of the discrete nonlinear Schr{\"o}dinger lattice initialized such that a very long transitory period of time in which standard Boltzmann statistics is insufficient is reached. Our study of the nonlinear system locked in this {\em non-Gibbsian} state focuses on the dynamics of discrete breathers (also called intrinsic localized modes). It is found that part of the energy spontaneously condenses into several discrete breathers. Although these discrete breathers are extremely long lived, their total number is found to decrease as the evolution progresses. Even though the total number of discrete breathers decreases we report the surprising observation that the energy content in the discrete breather population increases. We interpret these observations in the perspective of discrete breather creation and annihilation and find that the death of a discrete breather cause effective energy transfer to a spatially nearby discrete breather. It is found that the concepts of a multi-frequency discrete breather and of internal modes is crucial for this process. Finally, we find that the existence of a discrete breather tends to soften the lattice in its immediate neighborhood, resulting in high amplitude thermal fluctuation close to an existing discrete breather. This in turn nucleates discrete breather creation close to a already existing discrete breather

Note on SLE and logarithmic CFT

It is discussed how stochastic evolutions may be linked to logarithmic conformal field theory. This introduces an extension of the stochastic Loewner evolutions. Based on the existence of a logarithmic null vector in an indecomposable highest-weight module of the Virasoro algebra, the representation theory of the logarithmic conformal field theory is related to entities conserved in mean under the stochastic process.Comment: 10 pages, LaTeX, v2: version to be publishe

Magnetoinductive breathers in magnetic metamaterials

The existence and stability of discrete breathers (DBs) in one-dimensional and two-dimensional magnetic metamaterials (MMs), which consist of periodic arrangem ents (arrays) of split-ring resonators (SRRs), is investigated numerically. We consider different configurations of the SRR arrays, which are related to the relative orientation of the SRRs in the MM, both in one and two spatial dimensions. In the latter case we also consider anisotropic MMs. Using standard numerical methods we construct several types of linearly stable breather excitations both in Hamiltonian and dissipative MMs (dissipative breathers). The study of stability in both cases is performed using standard Floquet analysi s. In both cases we found that the increase of dimensionality from one to two spatial dimensions does not destroy the DBs, which may also exist in the case of moderate anisotropy (in two dimensions). In dissipative MMs, the dynamics is governed by a power balance between the mainly Ohmic dissipation and driving by an alternating magnetic field. In that case it is demonstrated that DB excitation locally alters the magnetic response of MMs from paramagnetic to diamagnetic. Moreover, when the frequency of the applied field approaches the SRR resonance frequency, the magnetic response of the MM in the region of the DB excitation may even become negative (extreme diamagnetic).Comment: 12 pages 15 figure

Simulation of transition dynamics to high confinement in fusion plasmas

The transition dynamics from the low (L) to the high (H) confinement mode in magnetically confined plasmas is investigated using a first-principles four-field fluid model. Numerical results are in close agreement with measurements from the Experimental Advanced Superconducting Tokamak - EAST. Particularly, the slow transition with an intermediate dithering phase is well reproduced by the numerical solutions. Additionally, the model reproduces the experimentally determined L-H transition power threshold scaling that the ion power threshold increases with increasing particle density. The results hold promise for developing predictive models of the transition, essential for understanding and optimizing future fusion power reactors

Research study of some RAM antennas Final report, 18 Nov. 1964 - 18 Jun. 1965

Input impedance and radiation pattern determinations for cylindrical gap, waveguide excited and circular waveguide slot antenna array

Hanle effect in coherent backscattering

We study the shape of the coherent backscattering (CBS) cone obtained when resonant light illuminates a thick cloud of laser-cooled rubidium atoms in presence of a homogenous magnetic field. We observe new magnetic field-dependent anisotropies in the CBS signal. We show that the observed behavior is due to the modification of the atomic radiation pattern by the magnetic field (Hanle effect in the excited state).Comment: 4 pages, 3 figure

Quantum transport in carbon nanotubes

Carbon nanotubes are a versatile material in which many aspects of condensed matter physics come together. Recent discoveries, enabled by sophisticated fabrication, have uncovered new phenomena that completely change our understanding of transport in these devices, especially the role of the spin and valley degrees of freedom. This review describes the modern understanding of transport through nanotube devices. Unlike conventional semiconductors, electrons in nanotubes have two angular momentum quantum numbers, arising from spin and from valley freedom. We focus on the interplay between the two. In single quantum dots defined in short lengths of nanotube, the energy levels associated with each degree of freedom, and the spin-orbit coupling between them, are revealed by Coulomb blockade spectroscopy. In double quantum dots, the combination of quantum numbers modifies the selection rules of Pauli blockade. This can be exploited to read out spin and valley qubits, and to measure the decay of these states through coupling to nuclear spins and phonons. A second unique property of carbon nanotubes is that the combination of valley freedom and electron-electron interactions in one dimension strongly modifies their transport behaviour. Interaction between electrons inside and outside a quantum dot is manifested in SU(4) Kondo behavior and level renormalization. Interaction within a dot leads to Wigner molecules and more complex correlated states. This review takes an experimental perspective informed by recent advances in theory. As well as the well-understood overall picture, we also state clearly open questions for the field. These advances position nanotubes as a leading system for the study of spin and valley physics in one dimension where electronic disorder and hyperfine interaction can both be reduced to a very low level.Comment: In press at Reviews of Modern Physics. 68 pages, 55 figure