Venture community: democratisation of entrepreneurship in developing economies

The motivation of this paper is to assist SMEs (mainly micro and informal enterprises) in developing economies to find the required resources to establish, or develop, their business. We introduce the concept of 'Venture Communities' to provide direct peer-to-peer connections between individuals and SMEs in all parts of the global market. We draw on the well-established concepts of networking, crowdfunding, living labs and value co-creation. The contribution we make lies in the introduction of a novel ecosystem, constructed by multiple actors, through dynamic and interconnected networks, accumulating resources for the benefit of all stakeholders of this community. Our model presents a challenge to the conventional conceptualizations of dyadic relationships between developed economies and emerging economies. Alternatively, we suggest anti-essentialist communities that are temporary constellation of social elements from all parts of the global market to create "hybridized and nomadic" (Laclau and Mouffe 1995) market arrangements

Patch Antenna for Measuring the Internal Temperature of Biological Objects Using the Near-Field Microwave Radiometric Method

The near-field microwave antenna with central frequency of 2.23 GHz has been designed and manufactured to be used as a part of the medical microwave radiometric system. Experimental studies of the reflection coefficient in different parts of the human body were conducted using the developed antenna. The experimental studies were carried out in a group of volunteers with normal somatic growth. The results of the experiments were used to perform the analysis of the potential errors in the measurements obtained via the developed antenna

Laser acceleration of ion beams

We consider methods of charged particle acceleration by means of high-intensity lasers. As an application we discuss a laser booster for heavy ion beams provided, e.g. by the Dubna nuclotron. Simple estimates show that a cascade of crossed laser beams would be necessary to provide additional acceleration to gold ions of the order of GeV/nucleon.Comment: 4 pages, 4 figures, Talk at the Helmholtz International Summer School "Dense Matter in heavy Ion Collisions and Astrophysics", August 21 - September 1, 2006, JINR Dubna, Russia; v2, misprints correcte

Controlling circular polarization of light emitted by quantum dots using chiral photonic crystal slab

We study the polarization properties of light emitted by quantum dots that are embedded in chiral photonic crystal structures made of achiral planar GaAs waveguides. A modification of the electromagnetic mode structure due to the chiral grating fabricated by partial etching of the wave\-guide layer has been shown to result in a high circular polarization degree $\rho_c$ of the quantum dot emission in the absence of external magnetic field. The physical nature of the phenomenon can be understood in terms of the reciprocity principle taking into account the structural symmetry. At the resonance wavelength, the magnitude of $|\rho_c|$ is predicted to exceed 98%. The experimentally achieved value of $|\rho_c|=81$% is smaller, which is due to the contribution of unpolarized light scattered by grating defects, thus breaking its periodicity. The achieved polarization degree estimated removing the unpolarized nonresonant background from the emission spectra can be estimated to be as high as 96%, close to the theoretical prediction

Construction of stations for applied research at the NICA accelerator complex

This paper presents the applied stations descriptio

Wireless digital traffic signs of the future

[EN] Traffic signs have come a long way since the first automobile was invented. They have long served the purpose of warning and guiding drivers and also enforcing the traffic laws governing speed, parking, turns, and stopping. In this study, the authors discuss the issues and challenges facing current traffic signs, and how it will evolve into a next-generation traffic sign architecture using advanced wireless communications technologies. With technological advances in the areas of wireless communications and embedded electronics and software, we foresee that, in the future, digital traffic sign posts will be capable of transmitting the traffic sign information wirelessly to road users, and this will transform our roads into intelligent roads, where signs will appear promptly and automatically on in-vehicle displays to alert the driver. There is no longer the need to watch out for traffic signs since the detection will be automatic and performed wirelessly. This transformation will lessen burden on the drivers, so that they can then focus more on the traffic ahead while driving. Also, this evolution into wireless digital sign posts will fit well with the vision of future smart cities, where smart transportation technologies will be present to transform how we drive and commute, yielding greater safety, ease, and assistance to drivers.Toh, CK.; Cano, J.; Fernandez-Laguia, C.; Manzoni, P.; Tavares De Araujo Cesariny Calafate, CM. (2019). Wireless digital traffic signs of the future. IET Networks. 8(1):74-78. https://doi.org/10.1049/iet-net.2018.5127S74788

Gating strategy for plasmablast enumeration after hepatitis B vaccination

B cell stimulation develops upon vaccination, thus causing occurrence of activated B cells (plasmoblasts) in bloodstream. Similar cells are also observed in some viral infections. The contents of plasmablasts may be a marker of successful vaccination, or a diagnostic feature of ongoing infection. The plasmablasts are normally represented by a small cell subpopulation which is not easy to detect. A study was performed with 15 healthy volunteers who were subjected to a single immunization with a recombinant vaccine against hepatitis B virus. To identify the plasmablasts, we have used labeled antibodies prepared in our laboratory. These reagents were previously validated for counting the plasmablasts. Different gating strategies for plasmablast gating have been compared. Upon staining of lymphocytes from immunized volunteers, we observed a distinct cluster of plasmablasts with CD27++CD38++ phenotype using the following antibody set: CD19-PE, CD3/CD14/CD16-FITC, CD27-PC5.5 and CD38-PC7. Inclusion of a CD20-FITC antibody into the panel caused an increase of CD27++CD38++ plasmablast ratio among CD19+ lymphocytes to > 60%. Upon substitution of CD38 antibody by anti-CD71, a distinct plasmablast cluster was again revealed, which contained ca. 5 per cent В cells. Two strategies for the plasmablast gating using the CD27/ CD38 and CD27/CD71 combinations were compared in dynamics with lymphocyte samples from a single vaccinated volunteer. When applying the CD27/CD38 combination, a sharp and pronounced plasmablast peak was registered on day 7 post-vaccination. With CD27/CD71 combination, the peak was extended between day 7 and day 14 following immunization. Hence, time kinetics of the CD27+CD71+ population proved to be different from occurrence of classic plasmablasts with CD27++CD38++ phenotype. This finding suggests that the CD27++CD71+population contains both plasmablasts and other types of activated B cells. A minor HBV surface antigen was prepared and labeled with phycoerythrin (HBsAg-PE), thus allowing to quantify the antigen-specific plasmablasts. The results of HBsAg-PE-based detection of antigen-specific cells were in compliance with the data obtained by ELISpot technique. At the present time, we use the original plasmablast gating technique for detection of activated B cells in SARS-CoV-2 infection. At the next step, this technique will be applied to sorting of antigen-specific B cells, thus permitting sequencing of Ig genes and design of novel human antibodies against viral antigens.B cell stimulation develops upon vaccination, thus causing occurrence of activated B cells (plasmoblasts) in bloodstream. Similar cells are also observed in some viral infections. The contents of plasmablasts may be a marker of successful vaccination, or a diagnostic feature of ongoing infection. The plasmablasts are normally represented by a small cell subpopulation which is not easy to detect. A study was performed with 15 healthy volunteers who were subjected to a single immunization with a recombinant vaccine against hepatitis B virus. To identify the plasmablasts, we have used labeled antibodies prepared in our laboratory. These reagents were previously validated for counting the plasmablasts. Different gating strategies for plasmablast gating have been compared. Upon staining of lymphocytes from immunized volunteers, we observed a distinct cluster of plasmablasts with CD27++CD38++ phenotype using the following antibody set: CD19-PE, CD3/CD14/CD16-FITC, CD27-PC5.5 and CD38-PC7. Inclusion of a CD20-FITC antibody into the panel caused an increase of CD27++CD38++ plasmablast ratio among CD19+ lymphocytes to > 60%. Upon substitution of CD38 antibody by anti-CD71, a distinct plasmablast cluster was again revealed, which contained ca. 5 per cent В cells. Two strategies for the plasmablast gating using the CD27/ CD38 and CD27/CD71 combinations were compared in dynamics with lymphocyte samples from a single vaccinated volunteer. When applying the CD27/CD38 combination, a sharp and pronounced plasmablast peak was registered on day 7 post-vaccination. With CD27/CD71 combination, the peak was extended between day 7 and day 14 following immunization. Hence, time kinetics of the CD27+CD71+ population proved to be different from occurrence of classic plasmablasts with CD27++CD38++ phenotype. This finding suggests that the CD27++CD71+ population contains both plasmablasts and other types of activated B cells. A minor HBV surface antigen was prepared and labeled with phycoerythrin (HBsAg-PE), thus allowing to quantify the antigen-specific plasmablasts. The results of HBsAg-PE-based detection of antigen-specific cells were in compliance with the data obtained by ELISpot technique. At the present time, we use the original plasmablast gating technique for detection of activated B cells in SARS-CoV-2 infection. At the next step, this technique will be applied to sorting of antigen-specific B cells, thus permitting sequencing of Ig genes and design of novel human antibodies against viral antigens

Particle Creation from Vacuum by Lorentz Violation

It is shown that the vacuum state in presence of Lorentz violation can be followed by a particle-full universe that represents the current status of the universe. In this model the modification in dispersion relation (Lorentz violation) is picked up representing the regime of quantum gravity. The result can be interpreted such that the existence of the particles is an evidence for quantum effects of gravity in the past. It is concluded that only the vacuum state is sufficient to appear the matter fields spontaneously after the process of semi-classical analysis.Comment: 9 pages, 2 figure