High-precision determination of the electric and magnetic radius of the proton

Using dispersion theory with an improved description of the two-pion continuum based on the precise Roy-Steiner analysis of pion-nucleon scattering, we analyze recent data from electron-proton scattering. This allows for a high-precision determination of the electric and magnetic radius of the proton, $r_E = (0.838^{+0.005}_{-0.004}{}^{+0.004}_{-0.003})\,$fm and $r_M = (0.847\pm{0.004}\pm{0.004})\,$fm, where the first error refers to the fitting procedure using bootstrap and the data while the second one refers to the systematic uncertainty related to the underlying spectral functions.Comment: 8 pages, 2 figures, more discussions and references added, version accepted for publication in Physics Letters

Dispersion-theoretical analysis of the electromagnetic form factors of the nucleon: Past, present and future

We review the dispersion-theoretical analysis of the electromagnetic form factors of the nucleon. We emphasize in particular the role of unitarity and analyticity in the construction of the isoscalar and isovector spectral functions. We present new results on the extraction of the nucleon radii, the electric and magnetic form factors and the extraction of $\omega$-meson couplings. All this is supplemented by a detailed calculation of the theoretical uncertainties, using bootstrap and Bayesian methods to pin down the statistical errors, while systematic errors are determined from variations of the spectral functions. We also discuss the physics of the time-like form factors and point out further issues to be addressed in this framework.Comment: 31 pages, 33 pages, commissioned review article for EPJ

Pseudoscalar mixing in J/psi and psi(2S) decay

Based on the branching fractions of J/psi(psi(2S))-> VP from different collaborations, the pseudoscalar mixing is extensively discussed with a well established phenomenological model. The mixing angle is determined to be -14 degree by fitting to the new world average if only quark content is considered. After taking into account the gluonic content in eta and eta prime simultaneously, the investigation shows that eta favors only consisting of light quarks, while the gluonic content of eta prime is Z_{eta prime}^2=0.30\pm0.24.Comment: 8 page

A Wave Function Describing Superfluidity in a Perfect Crystal

We propose a many-body wave function that exhibits both diagonal and off-diagonal long-range order. Incorporating short-range correlations due to interatomic repulsion, this wave function is shown to allow condensation of zero-point lattice vibrations and phase rigidity. In the presence of an external velocity field, such a perfect crystal will develop non-classical rotational inertia, exhibiting the supersolid behavior. In a sample calculation we show that the superfluid fraction in this state can be as large as of order 0.01 in a reasonable range of microscopic parameters. The relevance to the recent experimental evidence of a supersolid state by Chan and Kim is discussed.Comment: final version to be published in Journal of Statistical Mechanics: Theory and Experimen

Isomeric triazines exhibit unique profiles of bioorthogonal reactivity.

Expanding the scope of bioorthogonal reactivity requires access to new and mutually compatible reagents. We report here that 1,2,4-triazines can be tuned to exhibit unique reaction profiles with biocompatible strained alkenes and alkynes. Computational analyses were used to identify candidate orthogonal reactions, and the predictions were experimentally verified. Notably, 5-substituted triazines, unlike their 6-substituted counterparts, undergo rapid [4 + 2] cycloadditions with a sterically encumbered strained alkyne. This unique, sterically controlled reactivity was exploited for dual bioorthogonal labeling. Mutually orthogonal triazines and cycloaddition chemistries will enable new multi-component imaging applications

Isospin-conserving hadronic decay of the Ds1(2460){D_{s1}(2460)} into Dsπ+π−{D_s\pi^+\pi^-}

The internal structure of the charm-strange mesons $D_{s0}^*(2317)$ and $D_{s1}(2460)$ are subject of intensive studies. Their widths are small because they decay dominantly through isospin-breaking hadronic channels $D_{s0}^*(2317)^+\to D_s^+\pi^0$ and $D_{s1}(2460)^+\to D_s^{*+}\pi^0$. The $D_{s1}(2460)$ can also decay into the hadronic final states $D_s^+\pi\pi$, conserving isospin. In that case there is, however, a strong suppression from phase space. We study the transition $D_{s1}(2460)^+\to D_s^+\pi^+\pi^-$ in the scenario that the $D_{s1}(2460)$ is a $D^*K$ hadronic molecule. The $\pi\pi$ final state interaction is taken into account through dispersion relations. We find that the ratio of the partial widths of the $\Gamma(D_{s1}(2460)^+\to D_s^+\pi^+\pi^-)/\Gamma(D_{s1}(2460)^+\to D_s^{*+}\pi^0)$ obtained in the molecular picture is consistent with the existing experimental measurement. More interestingly, we demonstrate that the $\pi^+\pi^-$ invariant mass distribution shows a double bump structure, which can be used to disentangle the hadronic molecular picture from the compact state picture for the $D_{s1}(2460)^+$. Predictions on the $B_{s1}^0\to B_s^0\pi^+\pi^-$ are also made.Comment: 16 pages, 5 figure

Analysis of electrophysiological activation of the uterus during human labor contractions

This cohort study uses electromyometrial imaging to examine the underlying electrophysiological origins of human labor at the myometrium level

Geometry and optics calibration of WFCTA prototype telescopes using star light

The Large High Altitude Air Shower Observatory project is proposed to study high energy gamma ray astronomy ( 40 GeV-1 PeV ) and cosmic ray physics ( 20 TeV-1 EeV ). The wide field of view Cherenkov telescope array, as a component of the LHAASO project, will be used to study energy spectrum and compositions of cosmic ray by measuring the total Cherenkov light generated by air showers and shower maximum depth. Two prototype telescopes have been in operation since 2008. The pointing accuracy of each telescope is crucial to the direction reconstruction of the primary particles. On the other hand the primary energy reconstruction relies on the shape of the Cherenkov image on the camera and the unrecorded photons due to the imperfect connections between photomultiplier tubes. UV bright stars are used as point-like objects to calibrate the pointing and to study the optical properties of the camera, the spot size and the fractions of unrecorded photons in the insensitive areas of the camera.Comment: 5 pages, 6 figures, submitted to Chinese Physics

Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region

<p>Abstract</p> <p>Background</p> <p>Prader-Willi syndrome (PWS) is a neurobehavioral disorder characterized by neonatal hypotonia, childhood obesity, dysmorphic features, hypogonadism, mental retardation, and behavioral problems. Although PWS is most often caused by a paternal interstitial deletion of a 6-Mb region of chromosome 15q11-q13, the identity of the exact protein coding or noncoding RNAs whose deficiency produces the PWS phenotype is uncertain. There are also reports describing a PWS-like phenotype in a subset of patients with full mutations in the <it>FMR1 </it>(fragile X mental retardation 1) gene. Taking advantage of the human genome sequence, we have performed extensive sequence analysis and molecular studies for the PWS candidate region.</p> <p>Results</p> <p>We have characterized transcripts for the first time for two UCSC Genome Browser predicted protein-coding genes, <it>GOLGA8E </it>(golgin subfamily a, 8E) and <it>WHDC1L1 </it>(WAS protein homology region containing 1-like 1) and have further characterized two previously reported genes, <it>CYF1P1 </it>and <it>NIPA2</it>; all four genes are in the region close to the proximal/centromeric deletion breakpoint (BP1). <it>GOLGA8E</it> belongs to the golgin subfamily of coiled-coil proteins associated with the Golgi apparatus. Six out of 16 golgin subfamily proteins in the human genome have been mapped in the chromosome 15q11-q13 and 15q24-q26 regions. We have also identified more than 38 copies of <it>GOLGA8E</it>-like sequence in the 15q11-q14 and 15q23-q26 regions which supports the presence of a <it>GOLGA8E</it>-associated low copy repeat (LCR). Analysis of the 15q11-q13 region by PFGE also revealed a polymorphic region between BP1 and BP2. <it>WHDC1L1 </it>is a novel gene with similarity to mouse <it>Whdc1 </it>(WAS protein homology region 2 domain containing 1) and human JMY protein (junction-mediating and regulatory protein). Expression analysis of cultured human cells and brain tissues from PWS patients indicates that <it>CYFIP1 </it>and <it>NIPA2</it> are biallelically expressed. However, we were not able to determine the allele-specific expression pattern for <it>GOLGA8E </it>and <it>WHDC1L1 </it>because these two genes have highly related sequences that might also be expressed.</p> <p>Conclusion</p> <p>We have presented an updated version of a sequence-based physical map for a complex chromosomal region, and we raise the possibility of polymorphism in the genomic orientation of the BP1 to BP2 region. The identification of two new proteins <it>GOLGA8E</it> and <it>WHDC1L1</it> encoded by genes in the 15q11-q13 region may extend our understanding of the molecular basis of PWS. In terms of copy number variation and gene organization, this is one of the most polymorphic regions of the human genome, and perhaps the single most polymorphic region of this type.</p

QED and relativistic nuclear recoil corrections to the 413 nm tune-out wavelength for the 2\,^3S_1 state of helium

Comparison of high accuracy calculations with precision measurement of the 413 nm tune-out wavelength of the He(2\,^3S_1) state provides a unique test of quantum electro-dynamic (QED). We perform large-scale relativistic-configuration-interaction (RCI) calculations of the tune-out wavelength, that include the mass-shift operator, and fully account for leading relativistic nuclear recoil terms in the Dirac-Coulomb-Breit (DCB) Hamiltonian. We obtain the QED correction to the tune-out wavelength using perturbation theory, and the effect of finite nuclear size is also evaluated. The resulting tune-out wavelengths for the 2\,^3S_1(M_J=0) and 2\,^3S_1(M_J=\pm 1) states are 413.084 26(4) nm and 413.090 15(4) nm, respectively. Compared with the only current experimental value of 413.0938(9stat)(20syst) nm for the 2\,^3S_1(M_J=\pm 1) state, there is 1.8$\sigma$ discrepancy between present theoretical work and experiment, which stimulates further theoretical and higher-precision experimental investigations on the 413 nm tune-out wavelength. In addition, we also determine the QED correction for the static dipole polarizability of the He(2\,^3S_1) state to be 22.5 ppm, which may enable a new test of QED in the future.Comment: 6 pages; 2 figure