Non-universal gauge boson Z′Z' and the spin correlation of top quark pair production at e−e+e^{-}e^{+} colliders

In the off-diagonal basis, we discuss the contributions of the non-universal gauge boson $Z'$ predicted by the topcolor-assisted technicolor ($TC2$) model to the spin configurations and the spin correlation observable of the top quark pair production via the process $e^{-}e^{+}\to t\bar{t}$. Our numerical results show that the production cross sections for the like-spin states, which vanish in the standard model, can be significantly large as $M_{Z'}\approx \sqrt{S}$. With reasonable values of the $Z'$ mass $M_{Z'}$ and the coupling parameter $k_{1}$, $Z'$ exchange can generate large corrections to the spin correlation observable.Comment: 16 pages, 5 figure

Radiative corrections to the semileptonic and hadronic Higgs-boson decays H -> W W/Z Z -> 4 fermions

The radiative corrections of the strong and electroweak interactions are calculated for the Higgs-boson decays H -> WW/ZZ -> 4f with semileptonic or hadronic four-fermion final states in next-to-leading order. This calculation is improved by higher-order corrections originating from heavy-Higgs-boson effects and photonic final-state radiation off charged leptons. The W- and Z-boson resonances are treated within the complex-mass scheme, i.e. without any resonance expansion or on-shell approximation. The calculation essentially follows our previous study of purely leptonic final states. The electroweak corrections are similar for all four-fermion final states; for integrated quantities they amount to some per cent and increase with growing Higgs-boson mass M_H, reaching 7-8% at M_H \sim 500 GeV. For distributions, the corrections are somewhat larger and, in general, distort the shapes. Among the QCD corrections, which include corrections to interference contributions of the Born diagrams, only the corrections to the squared Born diagrams turn out to be relevant. These contributions can be attributed to the gauge-boson decays, i.e. they approximately amount to \alpha_s/\pi for semileptonic final states and 2\alpha_s/\pi for hadronic final states. The discussed corrections have been implemented in the Monte Carlo event generator PROPHECY4F.Comment: 29 pages, LaTeX, 30 postscript figure

Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds.

Implants formed of metals, bioceramics, or polymers may provide an alternative to autografts for treating large bone defects. However, limitations to each material motivate the examination of composites to capitalize on the beneficial aspects of individual components and to address the need for conferring bioactive behavior to the polymer matrix. We hypothesized that the inclusion of different bioceramics in a ceramic-polymer composite would alter the physical properties of the implant and the cellular osteogenic response. To test this, composite scaffolds formed from poly(lactide-co-glycolide) (PLG) and either hydroxyapatite (HA), β-tricalcium phosphate (TCP), or bioactive glass (Bioglass 45S®, BG) were fabricated, and the physical properties of each scaffold were examined. We quantified cell proliferation by DNA content, osteogenic response of human osteoblasts (NHOsts) to composite scaffolds by alkaline phosphatase (ALP) activity, and changes in gene expression by qPCR. Compared to BG-PLG scaffolds, HA-PLG and TCP-PLG composite scaffolds possessed greater compressive moduli. NHOsts on BG-PLG substrates exhibited higher ALP activity than those on control, HA-, or TCP-PLG scaffolds after 21 days, and cells on composites exhibited a 3-fold increase in ALP activity between 7 and 21 days versus a minimal increase on control scaffolds. Compared to cells on PLG controls, RUNX2 expression in NHOsts on composite scaffolds was lower at both 7 and 21 days, while expression of genes encoding for bone matrix proteins (COL1A1 and SPARC) was higher on BG-PLG scaffolds at both time points. These data demonstrate the importance of selecting a ceramic when fabricating composites applied for bone healing

Precision Measurements and Fermion Geography in the Randall-Sundrum Model Revisited

We re-examine the implications of allowing fermion fields to propagate in the five-dimensional bulk of the Randall-Sundrum (RS) localized gravity model. We find that mixing between the Standard Model top quark and its Kaluza Klein excitations generates large contributions to the rho parameter and consequently restricts the fundamental RS scale to lie above 100 TeV. To circumvent this bound we propose a `mixed' scenario which localizes the third generation fermions on the TeV brane and allows the lighter generations to propagate in the full five-dimensional bulk. We show that this construction naturally reproduces the observed m_c / m_t and m_s / m_b hierarchies. We explore the signatures of this scenario in precision measurements and future high energy collider experiments. We find that the region of parameter space that addresses the hierarchies of fermion Yukawa couplings permits a Higgs boson with a mass of 500 GeV and remains otherwise invisible at the LHC. However, the entire parameter region consistent with electroweak precision data is testable at future linear colliders. We briefly discuss possible constraints on this scenario arising from flavor changing neutral currents.Comment: 44 pages, 20 ps files; VII, typos fixed and refs adde

Updated Constraints on the Minimal Supergravity Model

Recently, refinements have been made on both the theoretical and experimental determinations of the i.) mass of the lightest Higgs scalar (m_h), ii.) relic density of cold dark matter in the universe (Omega_CDM h^2), iii.) branching fraction for radiative B decay BF(b \to s \gamma), iv.) muon anomalous magnetic moment (a_\mu), and v.) flavor violating decay B_s \to \mu^+\mu^-. Each of these quantities can be predicted in the MSSM, and each depends in a non-trivial way on the spectra of SUSY particles. In this paper, we present updated constraints from each of these quantities on the minimal supergravity (mSUGRA) model as embedded in the computer program ISAJET. The combination of constraints points to certain favored regions of model parameter space where collider and non-accelerator SUSY searches may be more focussed.Comment: 20 pages, 6 figures. Version published in JHE

The SKA view of the Neutral Interstellar Medium in Galaxies

Two major questions in galaxy evolution are how star-formation on small scales leads to global scaling laws and how galaxies acquire sufficient gas to sustain their star formation rates. HI observations with high angular resolution and with sensitivity to very low column densities are some of the important observational ingredients that are currently still missing. Answers to these questions are necessary for a correct interpretation of observations of galaxy evolution in the high-redshift universe and will provide crucial input for the sub-grid physics in hydrodynamical simulations of galaxy evolutions. In this chapter we discuss the progress that will be made with the SKA using targeted observations of nearby individual disk and dwarf galaxies.Comment: 22 pages, 4 figures, to appear as part of 'Neutral Hydrogen' in Proceedings 'Advancing Astrophysics with the SKA (AASKA14)', PoS(AASKA14)12

The High Energy Telescope on EXIST

The Energetic X-ray Imaging Survey Telescope (EXIST) is a proposed next generation multi-wavelength survey mission. The primary instrument is a High Energy telescope (HET) that conducts the deepest survey for Gamma-ray Bursts (GRBs), obscured-accreting and dormant Supermassive Black Holes and Transients of all varieties for immediate followup studies by the two secondary instruments: a Soft X-ray Imager (SXI) and an Optical/Infrared Telescope (IRT). EXIST will explore the early Universe using high redshift GRBs as cosmic probes and survey black holes on all scales. The HET is a coded aperture telescope employing a large array of imaging CZT detectors (4.5 m^2, 0.6 mm pixel) and a hybrid Tungsten mask. We review the current HET concept which follows an intensive design revision by the HET imaging working group and the recent engineering studies in the Instrument and Mission Design Lab at the Goddard Space Flight Center. The HET will locate GRBs and transients quickly (<10-30 sec) and accurately (< 20") for rapid (< 1-3 min) onboard followup soft X-ray and optical/IR (0.3-2.2 micron) imaging and spectroscopy. The broad energy band (5-600 keV) and the wide field of view (~90 deg x 70 deg at 10% coding fraction) are optimal for capturing GRBs, obscured AGNs and rare transients. The continuous scan of the entire sky every 3 hours will establish a finely-sampled long-term history of many X-ray sources, opening up new possibilities for variability studies.Comment: 10 pages, 6 figures, 3 tables, SPIE conference proceedings (UV, X-ray, and Gamma-Ray Space Instrumentation for Astronomy XVI, 7435-9

Inferring individual attributes from search engine queries and auxiliary information

Internet data has surfaced as a primary source for investigation of different aspects of human behavior. A crucial step in such studies is finding a suitable cohort (i.e., a set of users) that shares a common trait of interest to researchers. However, direct identification of users sharing this trait is often impossible, as the data available to researchers is usually anonymized to preserve user privacy. To facilitate research on specific topics of interest, especially in medicine, we introduce an algorithm for identifying a trait of interest in anonymous users. We illustrate how a small set of labeled examples, together with statistical information about the entire population, can be aggregated to obtain labels on unseen examples. We validate our approach using labeled data from the political domain. We provide two applications of the proposed algorithm to the medical domain. In the first, we demonstrate how to identify users whose search patterns indicate they might be suffering from certain types of cancer. In the second, we detail an algorithm to predict the distribution of diseases given their incidence in a subset of the population at study, making it possible to predict disease spread from partial epidemiological data

RooStatsCms: a tool for analyses modelling, combination and statistical studies

The RooStatsCms (RSC) software framework allows analysis modelling and combination, statistical studies together with the access to sophisticated graphics routines for results visualisation. The goal of the project is to complement the existing analyses by means of their combination and accurate statistical studies.Comment: Proceedings of the 11th Topical Seminar on Innovative Particle and Radiation Detectors. 4 pages and 5 figure

Unique Identification of Graviton Exchange Effects in e^+ e^- Collisions

Many types of new physics can lead to contact interaction-like modifications in e^+ e^- processes below direct production threshold. We examine the possibility of uniquely identifying the effects of graviton exchange, which are anticipated in many extra dimensional theories, from amongst this large set of models by using the moments of the angular distribution of the final state particles. In the case of the e^+ e^- --> f bar{f} process we demonstrate that this technique allows for the unique identification of the graviton exchange signature at the 5 sigma level for mass scales as high as 6 sqrt(s). The extension of this method to the e^+ e^- --> W^+ W^- process is also discussed.Comment: 21 pages, 3 figs, LaTe