2,941 research outputs found

    Table and charts of equilibrium normal-shock properties for hydrogen-helium mixtures with velocities to 70 km/sec. Volume 1: 0.95 H2-0.05 He (by volume)

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    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves into hydrogen-helium mixtures representative of postulated outer planet atmospheres. These results are presented in four volumes and the volmetric compositions of the mixtures are 0.95H2-0.05He in Volume 1, 0.90H2-0.10He in Volume 2, 0.85H2-0.15He in Volume 3, and 0.75H2-0.25He in Volume 4. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular-weight ratio, isentropic exponent, velocity, and species mole fractions. Incident (moving) shock velocities are varied from 4 to 70 km/sec for a range of initial pressure of 5 N/sq m to 100 kN/sq m. Results are applicable to shock-tube flows and for determining flow conditions behind the normal portion of the bow shock about a blunt body at high velocities in postulated outer planet atmospheres. The document is a revised version of the original edition of NASA SP-3085 published in 1974

    Tables and charts of equilibrium normal shock and shock tube solutions for pure CO2 with velocities to 16 km/second

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    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves in pure CO2, representative of Mars and Venus atmospheres. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular weight ratio, isentropic exponent, velocity and species mole fractions. Incident (moving) shock velocities are varied from 1 to 16 km/sec for a range of initial pressure of 5 Newtons per square meter to 500 kilo Newtons per square meter. The present results are applicable to shock tube flows, and to free-flight conditions for a blunt body at high velocities. Working charts illustrating idealized shock-tube performance with CO2 test gas and heated helium and hydrogen driver gases are also presented

    Performance implications of waste package emplacement orientation

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    Emplacement borehole orientation directly impacts many aspects of the Engineered Barrier System (EBS) and interactions with the near field environment. This paper considers the impacts of orientation on the hydrologic portion of the environment and its interactions with the EBS. The hydrologic environment is considered from a conceptual standpoint, the numerical analyses are left for subsequent work. As reported in this paper, several aspects of the hydrological environment are more favorable for long term performance of vertically oriented rather than horizontally oriented Waste Packages. 19 refs., 15 figs

    The Effectiveness of the Tarmac Reading Program

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    Statement of the Problem. It was the problem of this study to determine if educationally-deprived students participating in the TARMAC Diagnostic-Prescriptive Reading Program would show significant differences in reading abilities compared with educationally-deprived students who were not participants in that program. Limitations of the Study. The following limitations were imposed upon the study: 1. Initial grade levels in reading in control and experimental groups were measured by California Achievement Test scores as criteria for defining educationally deprived. 2. The 1975-76 school year was used as the experimental period. 3. The results were limited to one school and forty student participants. 4. The results of the experiment were measured by Stanford Achievement Test scores and social studies grades as a related course. (Abstract shortened.

    Do Sharks Swallow Their Young for Protection?

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    Heat-transfer distributions on biconics at incidence in hypersonic-hypervelocity He, N2, air, and CO2 flows

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    Laminar heat transfer rates were measured on spherically blunted, 13 deg/7 deg on axis and bent biconics (fore cone bent 7 deg upward relative to aft cone) at hypersonic hypervelocity flow conditions in the Langley Expansion Tube. Freestream velocities from 4.5 to 6.9 km/sec and Mach numbers from 6 to 9 were generated using helium, nitrogen, air, and carbon dioxide test gases, resulting in normal shock density ratios from 4 to 19. Angle of attack, referenced to the axis of the aft cone, was varied from 0 to 20 deg in 4 deg increments. The effect of nose bend, angle of attack, and real gas phenomena on heating distributions are presented along with comparisons of measurement to prediction from a code which solves the three dimensional parabolized Navier-Stokes equations

    Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C

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    Our previous studies demonstrated a relation between glutathionylation of cardiac myosin binding protein C (cMyBP-C) and diastolic dysfunction in a hypertensive mouse model stressed by treatment with salt, deoxycorticosterone acetate, and unilateral nephrectomy. Although these results strongly indicated an important role for S-glutathionylation of myosin binding protein C as a modifier of myofilament function, indirect effects of other post-translational modifications may have occurred. Moreover, we did not determine the sites of thiol modification by glutathionylation. To address these issues, we developed an in vitro method to mimic the in situ S-glutathionylation of myofilament proteins and determined direct functional effects and sites of oxidative modification employing Western blotting and mass spectrometry. We induced glutathionylation in vitro by treatment of isolated myofibrils and detergent extracted fiber bundles (skinned fibers) with oxidized glutathione (GSSG). Immuno-blotting results revealed increased glutathionylation with GSSG treatment of a protein band around 140 kDa. Using tandem mass spectrometry, we identified the 140 kDa band as cMyBP-C and determined the sites of glutathionylation to be at cysteines 655, 479, and 627. Determination of the relation between Ca(2+)-activation of myofibrillar acto-myosin ATPase rate demonstrated an increased Ca(2+)-sensitivity induced by the S-glutathionylation. Force generating skinned fiber bundles also showed an increase in Ca-sensitivity when treated with oxidized glutathione, which was reversed with the reducing agent, dithiothreitol (DTT). Our data demonstrate that a specific and direct effect of S-glutathionylation of myosin binding protein C is a significant increase in myofilament Ca(2+)-sensitivity. Our data also provide new insights into the functional significance of oxidative modification of myosin binding protein C and the potential role of domains not previously considered to be functionally significant as controllers of myofilament Ca(2+)-responsiveness and dynamics
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