1,904 research outputs found

    Corrections, clarifications, and additions to the 1996 checklist of the Alticinae of Central America : including Mexico (Coleoptera: Chrysomelidae)

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    In our checklist of the Alticinae of Central America and Mexico (Furth and Savini, 1996), there were some species whose status or generic combination needs clarification. In preparing the 1996 checklist the authors referred to some unpublished notes of Jan Bechyne in order to understand his system of alticine names and to clarify to which genera he considered various species to belong

    MICROSTRUCTURE AND CONNECTIVITY OF THE CEREBELLUM WITH ADVANCED DIFFUSION MRI IN HEALTH AND PATHOLOGY

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    The cerebellum contains most of the central nervous system neurons and it is classically known to be a key region for sensorimotor coordination and learning. However, its role in higher cognitive functions has been increasingly recognised, thus raising the interest of neuroscience and neuroimaging communities. Despite this, knowledge of cerebellar structure and function is still incomplete and the interpretation of experimental results is often problematic. For these and also technical reasons the cerebellum is still frequently disregarded in magnetic resonance imaging (MRI) studies. Therefore, the principal aim of this work was to use MRI to investigate cerebellar microstructure and macrostructural connectivity in health and pathology, focusing also on technical aspects of image acquisition. The starting point of each project described in the present thesis were techniques, models and pipelines currently accepted in clinical practice. The meeting of inadequacies or problems of such techniques raised questions that pushed research to a more fundamental level. This thesis has three main contributions. The first part presents a clinical study of cerebellar involvement in processing speed deficits in multiple sclerosis, where combined tractography and network science highlighted the importance of the cerebellum in patients\u2019 cognitive performance. Then a deeper investigation conducted on high-quality diffusion MRI data with advanced diffusion signal models showed that subregions of the cerebellar cortex are characterised by different microstructural features: this represents one of the very first attempts to use diffusion MRI to face the widespread idea of cerebellar cortex uniformity, which has been recently challenged by findings from other research fields, thus providing new perspectives for the study of cerebellar information processing in health and pathology. Finally, the emerging technical problems that hamper the study of small structures within the cerebellum were tackled by developing dedicated acquisition protocols that exploit reduced field-of-view techniques for 3T and 7T MRI scanners

    Pseudo Goldstone Bosons Phenomenology in Minimal Walking Technicolor

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    We construct the non-linear realized Lagrangian for the Goldstone Bosons associated to the breaking pattern of SU(4) to SO(4). This pattern is expected to occur in any Technicolor extension of the standard model featuring two Dirac fermions transforming according to real representations of the underlying gauge group. We concentrate on the Minimal Walking Technicolor quantum number assignments with respect to the standard model symmetries. We demonstrate that for, any choice of the quantum numbers, consistent with gauge and Witten anomalies the spectrum of the pseudo Goldstone Bosons contains electrically doubly charged states which can be discovered at the Large Hadron Collider.Comment: 25 pages, 5 figure

    First Principles Simulations of Boron Diffusion in Graphite

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    Boron strongly modifies electronic and diffusion properties of graphite. We report the first ab initio study of boron interaction with the point defects in graphite, which includes structures, thermodynamics, and diffusion. A number of possible diffusion mechanisms of boron in graphite are suggested. We conclude that boron diffuses in graphite by a kick-out mechanism. This mechanism explains the common activation energy, but large magnitude difference, for the rate of boron diffusion parallel and perpendicular to the basal plane. © 2007 The American Physical Society

    Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep

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    Transplacental transmission of bluetongue virus has been shown previously for the North European strain of serotype 8 (BTV-8) and for tissue culture or chicken egg-adapted vaccine strains but not for field strains of other serotypes. In this study, pregnant ewes (6 per group) were inoculated with either field or rescued strains of BTV-2 and BTV-8 in order to determine the ability of these viruses to cross the placental barrier. The field BTV-2 and BTV-8 strains was passaged once in Culicoides KC cells and once in mammalian cells. All virus inoculated sheep became infected and seroconverted against the different BTV strains used in this study. BTV RNA was detectable in the blood of all but two ewes for over 28 days but infectious virus could only be detected in the blood for a much shorter period. Interestingly, transplacental transmission of BTV-2 (both field and rescued strains) was demonstrated at high efficiency (6 out of 13 lambs born to BTV-2 infected ewes) while only 1 lamb of 12 born to BTV-8 infected ewes showed evidence of in utero infection. In addition, evidence for horizontal transmission of BTV-2 between ewes was observed. As expected, the parental BTV-2 and BTV-8 viruses and the viruses rescued by reverse genetics showed very similar properties to each other. This study showed, for the first time, that transplacental transmission of BTV-2, which had been minimally passaged in cell culture, can occur; hence such transmission might be more frequent than previously thought

    Psychiatric profile of motor subtypes of de novo drug-naĂŻve Parkinson's disease patients

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    Background: Parkinson's disease (PD) is a heterogeneous neurodegenerative disorder. It is well established that different motor subtypes of PD evolve with different clinical courses and prognoses. The complete psychiatric profile underlying these different phenotypes since the very early stage of the disease is debated. Aims of the study: We aimed at investigating the psychiatric profile of the three motor subtypes of PD (akinetic-rigid, tremor-dominant, and mixed) in de novo drug-naĂŻve patients with PD. Methods: Sixty-eight patients with PD, divided into 39 akinetic-rigid (AR), seven mixed (MIX), and 22 tremor-dominant (TD) patients underwent a complete assessment of psychiatric, cognitive, and motor symptoms. Results: No significant differences were found among groups. Conclusions: Our results suggest that a differentiation of the psychiatric symptoms associated with specific motor subtypes of PD is not detectable in de novo drug-naĂŻve patients. Previous evidence that emerges later along the disease progression may be a consequence of the dopaminergic and nondopaminergic damage increase

    Absolute calibration and beam reconstruction of MITO (a ground-based instrument in the millimetric region)

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    An efficient sky data reconstruction derives from a precise characterization of the observing instrument. Here we describe the reconstruction of performances of a single-pixel 4-band photometer installed at MITO (Millimeter and Infrared Testagrigia Observatory) focal plane. The strategy of differential sky observations at millimeter wavelengths, by scanning the field of view at constant elevation wobbling the subreflector, induces a good knowledge of beam profile and beam-throw amplitude, allowing efficient data recovery. The problems that arise estimating the detectors throughput by drift scanning on planets are shown. Atmospheric transmission, monitored by skydip technique, is considered for deriving final responsivities for the 4 channels using planets as primary calibrators.Comment: 14 pages, 6 fiugres, accepted for pubblication by New Astronomy (25 March

    Characterization of cerebro-cerebellar structural connections using high-quality diffusion MRI data

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    Finding home: the final step of the pigeons' homing process studied with a GPS data logger

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    Experiments have shown that homing pigeons are able to develop navigational abilities even if reared and kept confined in an aviary, provided that they are exposed to natural winds. These and other experiments performed on inexperienced birds have shown that previous homing experiences are not necessary to determine the direction of displacement. While the cues used in the map process for orienting at the release site have been extensively investigated, the final step of the homing process has received little attention by researchers. Although there is general agreement on the relevance of visual cues in navigation within the home area, there is a lack of clear evidence. In order to investigate the final step of the homing process, we released pigeons raised under confined conditions and others that had been allowed to fly freely around the loft and compared their flight paths recorded with a Global-Positioning-System logger. Our data show that a limited view of the home area impairs the pigeons' ability to relocate the loft at their first homing flight, suggesting that the final step of the homing process is mediated via recognition of familiar visual landmarks in the home area

    Small bodies science with the Twinkle space telescope

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    © 2019 Society of PhotoOptical Instrumentation Engineers (SPIE). Twinkle is an upcoming 0.45-m space-based telescope equipped with a visible and two near-infrared spectrometers covering the spectral range 0.4 to 4.5 μm with a resolving power R 250 (λ 2.42 μm). We explore Twinkle's capabilities for small bodies science and find that, given Twinkle's sensitivity, pointing stability, and spectral range, the mission can observe a large number of small bodies. The sensitivity of Twinkle is calculated and compared to the flux from an object of a given visible magnitude. The number, and brightness, of asteroids and comets that enter Twinkle's field of regard is studied over three time periods of up to a decade. We find that, over a decade, several thousand asteroids enter Twinkle's field of regard with a brightness and nonsidereal rate that will allow Twinkle to characterize them at the instrumentation's native resolution with SNR > 100. Hundreds of comets can also be observed. Therefore, Twinkle offers researchers the opportunity to contribute significantly to the field of Solar System small bodies research
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