1,448 research outputs found

    On the Solution to Octic Equations

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    We present a novel decomposition method to decompose an eighth-degree polynomial equation, into its two constituent fourth-degree polynomials, as factors, leading to its solution. The salient feature of the octic equation solved here is that, the sum of its four roots being equal to the sum of the remaining four roots. We derive the condition to be satisfied by coefficients so that the given octic is solvable by the proposed method

    Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes

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    Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need. Toward the goal of informing T1D biomarker strategies, we profiled coding and noncoding RNAs in human islet-derived exosomes and identified RNAs that were differentially expressed under proinflammatory cytokine stress conditions. Human pancreatic islets were obtained from cadaveric donors and treated with/without IL-1β and IFN-γ. Total RNA and small RNA sequencing were performed from islet-derived exosomes to identify mRNAs, long noncoding RNAs, and small noncoding RNAs. RNAs with a fold change ≥1.3 and a p-value <0.05 were considered as differentially expressed. mRNAs and miRNAs represented the most abundant long and small RNA species, respectively. Each of the RNA species showed altered expression patterns with cytokine treatment, and differentially expressed RNAs were predicted to be involved in insulin secretion, calcium signaling, necrosis, and apoptosis. Taken together, our data identify RNAs that are dysregulated under cytokine stress in human islet-derived exosomes, providing a comprehensive catalog of protein coding and noncoding RNAs that may serve as potential circulating biomarkers in T1D

    DATA Analytics of Agriculture Production, Wages and Income in Rural Areas of India using Big Data and Python Matplot Lib

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    Agriculture Sector is the major contribution in GDP growth rate of India and Most of the Rural India it will become major resource of Income generator it contains different sectors like paddy, poultry, fisheries, Milk, and other crops. In this paper we studied general, commercial, dairy and other related Agricultural out comes and their Incomes and wages. In this paper we are performing different Data Analytics by taking parameters Daily wages, Income and production of Rural India. In this we are using Big Data Hive and Python Matplotlib to produce Graphical Analytical Reports. and finding results of different crops and daily wages of rural workers. The results we are finding year of production, crop wise production, crop wise and sector wise wages and Income of different crops. In this paper we collected Data and sample Analytical Reports from Agriculture Statistics Ministry of Agriculture, Co operation & Farmers Welfare and Data.gov.in . we are revealing different Analytical Reports regarding wages, Income and Production

    A novel predictive optimization scheme for energy-efficient reliable operation of a sensor in dynamic scenarios

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    Wireless Sensor Network (WSN) has been studied for more than a decades that resulted in evolution of the significant applications towards assisting in sensing physical information from human inaccesible area. It was also observed from existing sysem that energy attribute is the root cause of majority of the problems associated with WSN that also gives rise to various operational reliability issue. Therefore, the prime goal of the proposed study is to present a novel predictive optimization approach of data fusion in order to jointly address the problems associated with energy efficiency and reliable operation of sensor nodes in WSN. An analytical research approach is carried out in order to ensure that a time-based synchronization scheme contributes to offer an evolutionary approach towards significant energy optimization. A simulation-based benchmarking analysis is carried out to find that proposed system offers good energy-efficient performance in comparison to existing approaches

    Quality of Service Issues for Reinforcement Learning Based Routing Algorithm for Ad-Hoc Networks

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    Mobile ad-hoc networks are dynamic networks which are decentralized and autonomous in nature. Many routing algorithms have been proposed for these dynamic networks. It is an important problem to model Quality of Service requirements on these types of algorithms which traditionally have certain limitations. To model this scenario we have considered a reinforcement learning algorithm SAMPLE. SAMPLE promises to deal effectively with congestion and under high traffic load. As it is natural for ad-hoc networks to move in groups, we have considered the various group mobility models. The Pursue Mobility Model with its superiormobilitymetrics exhibits better performance. At the data link layer we have considered IEEE 802.11e, a MAC layer which has provisions to support QoS. As mobile ad-hoc networks are constrained by resources like energy and bandwidth, it is imperative for them to cooperate in a reasonably selfish manner. Thus, in this paper we propose cooperation with a moderately punishing algorithm based on game theory. The proposed algorithm in synchronization with SAMPLE yields better results on IEEE 802.11e

    Information Retrieval based on Content and Location Ontology for Search Engine (CLOSE)

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    This paper mainly focuses on the personalization of the search engine based on data mining technique, such that user preferences are taken into consideration. Clickthrough data is applied on the user profile to mine the user preferences in order to extract the features to know in which users are really interested. The basic idea behind the concept is to construct the content and location ontology2019;s, where content represent the previous search records of the user and location refer to current location of user. SpyNB is the approach used to mining the user preferences from the Clickthrough data. The ranked support vector machine (RVSM) is performed on the searched results in order to display results according to user preferences by considering Clickthrough data

    Analytical Modelling of Power Efficient Reliable Operation of Data Fusion in Wireless Sensor Network

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    Irrespective of inclusion of Wireless Sensor Network (WSN) in majority of the research proposition for smart city planning, it is still shrouded with some significant issues. A closer look into problems in WSN shows that energy parameter is the origination point of majority of the other problems in resource-constrained sensors as well as it significant minimizes the reliability in standard sensory operation in adverse environment. Therefore, this manuscript presents a novel analytical model that is meant for establishing a well balance between energy efficiency over multi-path data forwarding and reliable operation with improved network performance. The complete process is emphasized during data fusion stage to ensure data quality too. A simulation study has been carried out using benchmarked test-bed of MEMSIC nodes to find that proposed system offers good energy conservation process during data fusion operation as well as it also ensure good reliable operation in comparison to existing system
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