Circular dichroism in photoelectron angular distributions from two‐color (1+1) REMPI of NO

A detailed experimental and theoretical study of dichroic effects in photoelectron angular distributions is reported for (1+1), two‐color REMPI of NO via the A^ 2Σ^+, v=0 state. Optically aligned A state rotational levels are probed through ionization by circularly polarized light. Resultant photoelectron angular distributions exhibit significant left–right asymmetry, the phase and magnitude of which are shown to be related to the curvature of the excited state M_J distribution. Theoretical calculations involving a full ab initio treatment of the ionization dynamics result in circularly dichroic angular distribution (CDAD) parameters in good agreement with those derived experimentally. Additional effects including hyperfine depolarization and coherence are also discussed in relation to the observed CDAD data

MICROEMULSIONS: PLATFORM FOR IMPROVEMENT OF SOLUBILITY AND DISSOLUTION OF POORLY SOLUBLE DRUGS

ABSTRACTThis study reviews that solubilization of lipophilic drugs with low aqueous solubility has been a major trust area in recent years. It can be seen thatthere is a real and continuing need for the development of effective drug delivery systems for poorly water-soluble drugs to enhance their absorptionand bioavailability. One such approach might be pharmaceutical microemulsions as they have emerged as potential solubility enhancing technologies.Microemulsion system has considerable potential to act as a drug delivery vehicle by incorporating a wide range of drug molecules. Microemulsionhas got advantage like excellent thermodynamic stability, high drug solubilization capacity, improved oral bioavailability and protection againstenzymatic hydrolysis. This review focuses on the basic concept, formulation, characterization, and recent advances in microemulsions as novel drugdelivery system.Keywords: Microemulsion, Lipophilicity, Solubilization, Bioavailability, Phase behavior

Polarization--universal rejection filtering by ambichiral structures made of indefinite dielectric--magnetic materials

An ambichiral structure comprising sheets of an anisotropic dielectric material rejects normally incident plane waves of one circular polarization (CP) state but not of the other CP state, in its fundamental Bragg regime. However, if the same structure is made of an dielectric--magnetic material with indefinite permittivity and permeability dyadics, it may function as a polarization--universal rejection filter because two of the four planewave components of the electromagnetic field phasors in each sheet are of the positive--phase--velocity type and two are of the negative--phase--velocity type.Comment: Cleaned citations in the tex

Relativistic calculations of the lifetimes and hyperfine structure constants in 67^{67}Zn+^{+}

This work presents accurate {\it ab initio} determination of the magnetic dipole (M1) and electric quadrupole (E2) hyperfine structure constants for the ground and a few low-lying excited states in $^{67}$Zn$^{+}$, which is one of the interesting systems in fundamental physics. The coupled-cluster (CC) theory within the relativistic framework has been used here in this calculations. Long standing demands for a relativistic and highly correlated calculations like CC can be able to resolve the disagreements among the lifetime estimations reported previously for a few low-lying states of Zn$^{+}$. The role of different electron correlation effects in the determination of these quantities are discussed and their contributions are presented.Comment: 9 pages, 1 figure. submitted to J. Phys. B Fast Trac

Magnetostructural and magnetocaloric properties of bulk LaCrO3 system

We studied the magnetic properties of bulk LaCrO3; a GdFeO3-type distorted perovskite, with a predominant antiferromagnetic phase transition at ~ 290 K. The bulk LaCrO3 exhibits intrinsic weak ferromagnetism at room temperature, which may arise due to the tilting of CrO6 octahedra, resulting in a non-zero net magnetic moment, as confirmed from the magnetization measurements. A broad magnetically-induced entropy change (-{\Delta}S) is observed with the maximum at 290 K, close to room temperature in LaCrO3 system.Comment: 13 Pages and 3 Figures Submitted to the Journal Physics Letter A on 15 March 201

Holographic inflation in non-static plane symmetric space-time

The current analysis uses the non-static plane symmetric space-time to dynamically examine the holographic dark energy model as a candidates of IR cut-offs (specifically Hubble's and Granda-Oliveros cut-off). Using the Markov Chain Monte Carlo (MCMC) method, we estimate the best fit values for the model parameters imposed from the combined datasets of $CC+SC+BAO$. Now, it has been found that the characteristics of space-time that have been addressed and formulated using both models are flat universe and observed that the model appears to be in good agreement with the observations. In addition, we investigate the behavior of equation of state parameters along with the energy conditions. Finally, we found that in both the cut-offs the models predict that the present and late universe are accelerating and the equation of state parameter behaves like the quintessence model.Comment: 15-pages; 13-figure

Alzheimer Detection System Using Hybrid Deep Convolutional Neural Network

Alzheimer’s disease of the sixth leading causes of death in the United States of America is projected to grow to the third place of all causes of death for the elderly soon to cancer and heart decease. Timely detection and prevention are crucial to it. AD detection is based on multiple medical examinations which all lead to extensive multivariate heterogeneous data. This factor makes manual comparison, evaluation, and analysis hardly possible. The hereby study proposes a new approach to the detection of AD at the earliest stage hybrid deep learning algorithms. Several feature extraction and selection draw possible features. The method involves InceptionV3 and DenseNet for both pre-processing and classification tasks, while MobileNet enables data pre-processing and object detection. Experimental results with 100 epochs and 15 hidden layers show InceptionV3 has an accuracy of 98%, which outperforms other models available. The comparative analysis with other CNN models endorses the proposed method, achieving the highest performance across the board from our system

Patterns of Individual Shopping Behavior

Much of economic theory is built on observations of aggregate, rather than individual, behavior. Here, we present novel findings on human shopping patterns at the resolution of a single purchase. Our results suggest that much of our seemingly elective activity is actually driven by simple routines. While the interleaving of shopping events creates randomness at the small scale, on the whole consumer behavior is largely predictable. We also examine income-dependent differences in how people shop, and find that wealthy individuals are more likely to bundle shopping trips. These results validate previous work on mobility from cell phone data, while describing the unpredictability of behavior at higher resolution.Comment: 4 pages, 5 figure

Comparative evaluation of efficacy of terbinafine and itraconazole in treatment of tinea cruris

Background: In a hot and humid country like India, the prevalence of superficial mycotic infections is on the rise due to contributing environmental and demographic factors. In this study, we sought to assess the efficacies of two oral antifungal drugs, Itraconazole (a traditional azole) and Terbinafine (the only orally available allylamine). The two drugs were analyzed to see whether they differed significantly in their cure rates of tinea cruris. Since data, that compares only systemically administered Itraconazole and Terbinafine in the treatment of tinea cruris, is limited, this study becomes imperative.Methods: 60 patients, all clinically confirmed cases of tinea cruris and belonging to the age group of 18-65 years, were recruited for this prospective study. Patients were then randomly divided into groups A and B and followed-up for a month. Group A received cap. Itraconazole 100 mg, twice a day, for 15 days while group B received tab. Terbinafine 250 mg, once a day, for 4 weeks. Both groups were given topical 2% Sertaconazole that had to be continued for 8 weeks. During the 4 visits, scores for the 3 parameters (erythema, pruritis and scaling) were calculated and recorded for statistical analysis.Results: Authors observed that majority of the patients were exposed to hot and humid environment that contributed to sweating and poor personal hygiene. The changes in scores of erythema, pruritis and scaling from the baseline visit for both, Itraconazole and Terbinafine, were statistically significant at week 4 with P < 0.05 for all parameters. But the difference between the scores of the two drugs was not found to be statistically significant.Conclusions: Although the sample size of this study was small and the data was limited, findings of this study supported that both Itraconazole and Terbinafine were highly effective in the treatment of tinea cruris

Computing welfare losses from data under imperfect competition with heterogeneous goods

We study the percentage of welfare losses (PWL) yielded by imperfect competition under product differentiation. When demand is linear, if prices, outputs, costs and the number of firms can be observed, PWL is arbitrary in both Cournot and Bertrand equilibria. If in addition, the elasticity of demand (resp. cross elasticity of demand) is known, we can calculate PWL in Cournot (resp. Bertrand) equilibrium. When demand is isoelastic and there are many firms, PWL can be computed from prices, outputs, costs and the number of .rms. In all these cases we find that price-marginal cost margins and demand elasticities may influence PWL in a counterintuitive way. We also provide conditions under which PWL increases or decreases with concentration