Recursion relations, Helicity Amplitudes and Dimensional Regularization

Using the method of on-shell recursion relations we compute tree level amplitudes including D-dimensional scalars and fermions. These tree level amplitudes are needed for calculations of one-loop amplitudes in QCD involving external quarks and gluons.Comment: 28 pages, 6 figures, clarifications adde

Disseminated chlorellosis in a dog

An adult dog with ataxia and a lingual mass, previously diagnosed as protothecosis, was euthanized. At the postmortem examination, the lingual mass, regions of the lungs and hilar lymph nodes, liver, mesenteric and sublumbar lymph nodes, and spinal meninges had pronounced green discoloration. Histologically, pyogranulomatous inflammation and algal organisms were found in the tongue, spinal meninges, hilar and mesenteric lymph nodes, liver, and lung. The algae had cell walls positive for periodic acid-Schiff and cytoplasmic granules. Ultrastructurally, the algae had a well-defined cell wall, stacks of grana and thylakoid membrane, and dense bodies, typical of starch granules. The organisms were identified as Chlorella, a green alga, based on the results of histochemistical and electron microscopic examination. To the author's knowledge this is the first report of disseminated Chlorella infection and the first report in a companion animal.The published version of this article may be found at http://www.vetpathology.org/cgi/content/abstract/46/3/43

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

Off-target binding of hydrophobic drugs can lead to unwanted side effects, either through specific or non-specific binding to unintended membrane protein targets. However, distinguishing the binding of drugs to membrane proteins from that of detergents, lipids and cofactors is challenging. Here, we use high-resolution mass spectrometry to study the effects of HIV protease inhibitors on the human zinc metalloprotease ZMPSTE24. This intramembrane protease plays a major role in converting prelamin A to mature lamin A. We monitored the proteolysis of farnesylated prelamin A peptide by ZMPSTE24 and unexpectedly found retention of the C-terminal peptide product with the enzyme. We also resolved binding of zinc, lipids and HIV protease inhibitors and showed that drug binding blocked prelamin A peptide cleavage and conferred stability to ZMPSTE24. Our results not only have relevance for the progeria-like side effects of certain HIV protease inhibitor drugs, but also highlight new approaches for documenting off-target drug binding

Changes in Pasture Growth Rate Due to Fertiliser and Grazing Management

It is imperative that sheep production systems in southern Australia continue to be refined so producers remain financially viable but at the same time the environment is not degraded. As part of a national thrust for development and promotion of better production systems, one research site has been established in Victoria where pastures and animal production are measured together with water and nutrient movement. Results for pasture growth rates over two years are presented here and will be used to develop best industry practice at completion of the project

Graduate Teaching Assistant Training: Preparing Instructors to Assist ESL Students in the Introductory Public Speaking Course

Much research identifies the need to assist English as a Second Language (ESL) students in our classrooms. Some communication educators have addressed this need by enrolling students in special sections of introductory courses for ESL students only. With a focus specifically on graduate teaching assistant (GTA) training, this paper suggests ways to assist ESL students, along with native speaking students, enrolled in regular sections of the introductory public speaking course. We first identify steps for assessing whether an ESL student is appropriately enrolled in a course. We then focus on ways instructors can assist ESL students with: 1) pronunciation, comprehensibility, and listening, 2) thinking rhetorically, and 3) delivery skills

Maintaining Relationships With Supply Chain Partners: A Case Study

This case study describes efforts of a market leader in the communication infrastructure industry to assess the relationships they have developed with their global supply chain partners.  Changes in the industry have resulted in geographic shifts of existing and potential supply chain suppliers and customers.  In an effort to determine if commitment to customer service has resulted in increased customer satisfaction and loyalty, research was conducted to assess their performance.  The results of this research were compared to previous research to determine if their service program has successfully differentiated them from their competitors

Thundermist Health Center: Extending Pharmaceutical Services To Underserved Patients

This paper describes a not-for-profit healthcare providers strategy to provide its economically disadvantaged patients with access to low cost pharmaceuticals. Initially, an in-house pharmacy was established, supported by a satellite distribution system using a telepharmacy solution to extend medications to its patients at remote sites. New federal legislation which provided access to low cost insurance through Medicare Part D to many of the providers disadvantaged patients, along with state licensing requirements forced the healthcare provider to reassess the economics of its pharmaceutical distribution system and seek other alternatives. Among the alternatives the healthcare provider considered was partnering with for-profit pharmaceutical companies in order to reach their patients

What happens when you tell someone you self-injure? The effects of disclosing NSSI to adults and peers

Background: Non-suicidal self-injury (NSSI) is associated with significant adverse consequences, including increased risk of suicide, and is a growing public health concern. Consequently, facilitating help-seeking in youth who self-injure is an important goal. Although young people who disclose their NSSI typically confide in peers and family, it is unclear how this disclosure and related variables (e.g. support from family and friends, coping behaviours, reasons for living) affect help-seeking over time. The aim of this study was to advance understanding of the impact of disclosure of NSSI by young people and to investigate these effects over time. Methods: A sample of 2637 adolescents completed self-report questionnaires at three time points, one year apart. Results: Of the sample, 526 reported a history of NSSI and 308 of those who self-injured had disclosed their behaviour to someone else, most commonly friends and parents. Conclusions: Overall, we observed that disclosure of NSSI to parents facilitates informal help-seeking, improves coping and reduces suicidality, but that disclosure to peers might reduce perceived social support and encourage NSSI in others. We discuss these findings in light of their clinical and research implications