248 research outputs found
Thermal Testing of the Heatshield for Extreme Entry Environment Technology (HEEET) TPS
The testing of a thermal protection system (TPS) in multiple arc jets and laser facilities is critical not only to determine the ability of a material to withstand the harsh aerothermal environments but is also required to collect relevant data that allows construction of a thermal response model of the TPS for flight design. The present talk provides an overview of recent arcjet testing of the HEEET material, one of the families of materials from the 3D Woven TPS program, being developed under NASAs Heatshield for Extreme Entry Environment Technology (HEEET) project
Biosensors for EVA: Muscle Oxygen and pH During Walking, Running and Simulated Reduced Gravity
During lunar excursions in the EVA suit, real-time measurement of metabolic rate is required to manage consumables and guide activities to ensure safe return to the base. Metabolic rate, or oxygen consumption (VO2), is normally measured from pulmonary parameters but cannot be determined with standard techniques in the oxygen-rich environment of a spacesuit. Our group developed novel near infrared spectroscopic (NIRS) methods to calculate muscle oxygen saturation (SmO2), hematocrit, and pH, and we recently demonstrated that we can use our NIRS sensor to measure VO2 on the leg during cycling. Our NSBRI-funded project is looking to extend this methodology to examine activities which more appropriately represent EVA activities, such as walking and running and to better understand factors that determine the metabolic cost of exercise in both normal and lunar gravity. Our 4 year project specifically addresses risk: ExMC 4.18: Lack of adequate biomedical monitoring capability for Constellation EVA Suits and EPSP risk: Risk of compromised EVA performance and crew health due to inadequate EVA suit systems
An FPGA Implementation to Detect Selective Cationic Antibacterial Peptides
Exhaustive prediction of physicochemical properties of peptide sequences is used in different areas of biological research. One example is the identification of selective cationic antibacterial peptides (SCAPs), which may be used in the treatment of different diseases. Due to the discrete nature of peptide sequences, the physicochemical properties calculation is considered a high-performance computing problem. A competitive solution for this class of problems is to embed algorithms into dedicated hardware. In the present work we present the adaptation, design and implementation of an algorithm for SCAPs prediction into a Field Programmable Gate Array (FPGA) platform. Four physicochemical properties codes useful in the identification of peptide sequences with potential selective antibacterial activity were implemented into an FPGA board. The speed-up gained in a single-copy implementation was up to 108 times compared with a single Intel processor cycle for cycle. The inherent scalability of our design allows for replication of this code into multiple FPGA cards and consequently improvements in speed are possible. Our results show the first embedded SCAPs prediction solution described and constitutes the grounds to efficiently perform the exhaustive analysis of the sequence-physicochemical properties relationship of peptides
PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposition of β-sheet rich aggregates. Recent evidence suggests that the misfolding mechanism is context-dependent, and that properties of the host protein, including the domain architecture and location of the repeat tract, can modulate aggregation. In order to allow the bioinformatic investigation of the context of polyglutamines, we have constructed a database, PolyQ (http://pxgrid.med.monash.edu.au/polyq). We have collected the sequences of all human proteins containing runs of seven or more glutamine residues and annotated their sequences with domain information. PolyQ can be interrogated such that the sequence context of polyglutamine repeats in disease and non-disease associated proteins can be investigated
Recommended from our members
Investigation of the Effect of Microstructure on the R-Curve Behavior of Metal-Ceramic Composites
An investigation was made into the effect of microstructure on the peak toughness and shape of the crack growth resistance curves for two ceramic-metal composites. An Al{sup 2}O{sup 3}/Al composite formed by Reactive Metal Penetration was used along with an AlN/Al composite formed using a reactive infiltration technique. The results indicate that the toughness increases with an increase in the volume fraction of the metal phase for a particular composite composition, and the peak toughness and shape of the R-Curve also depend on the composite microstructure and metal composition
Superconductivity in the Intercalated Graphite Compounds C6Yb and C6Ca
In this letter we report the discovery of superconductivity in the
isostructural graphite intercalation compounds C6Yb and C6Ca, with transition
temperatures of 6.5K and 11.5K respectively. A structural characterisation of
these compounds shows them to be hexagonal layered systems in the same class as
other graphite intercalates. If we assume that all the outer s-electrons are
transferred from the intercalant to the graphite sheets, then the charge
transfer in these compounds is comparable to other superconducting graphite
intercalants such as C8K 1,2 . However, the superconducting transition
temperatures of C6Yb and C6Ca are up to two orders of magnitude greater.
Interestingly, superconducting upper critical field studies and resistivity
measurements suggest that these compounds are significantly more isotropic than
pure graphite. This is unexpected as the effect of introducing the intercalant
is to move the graphite layer further apart.Comment: 2 Figures. Please see accompanying theoretical manuscript,
"Electronic Structure of the Superconducting Graphite Intercalates" by Csanyi
et al., cond-mat/050356
Heatshield for Extreme Entry Environment Technology (HEEET) - Enabling Missions Beyond Heritage Carbon Phenolic
This poster provides an overview of the requirements, design, development and testing of the 3D Woven TPS being developed under NASA's Heatshield for Extreme Entry Environment Technology (HEEET) project. Under this current program, NASA is working to develop a Thermal Protection System (TPS) capable of surviving entry into Venus or Saturn. A primary goal of the project is to build and test an Engineering Test Unit (ETU) to establish a Technical Readiness Level (TRL) of 6 for this technology by 2017
Heatshield for Extreme Entry Environment Technology (HEEET) TPS for Ice Giants Probe Missions
This poster provides an overview of the requirements, design, development and testing of the 3D Woven TPS being developed under NASAs Heatshield for Extreme Entry Environment Technology (HEEET) project. Under this current program, NASA is working to develop a Thermal Protection System (TPS) capable of surviving entry into Saturn. A primary goal of the project is to build and test an Engineering Test Unit (ETU) to establish a Technical Readiness Level (TRL) of 6 for this technology by 2018. Poster also discusses use of HEEET TPS for probe missions to the Ice Giants, Uranus and Neptune
Heatshield for Extreme Entry Environment Technology (HEEET) Enabling Missions Beyond Heritage Carbon Phenolic
Future NASA robotic missions utilizing an entry system into Venus and the outer planets, results in extremely high entry conditions that exceed the capabilities of state of the art low to mid density ablators such as PICA or AVCOAT. Previously, mission planners had to assume the use of fully dense carbon phenolic heatshields similar to what was flown on Pioneer Venus or Galileo. Carbon phenolic is a robust TPS material, however, its high density and relatively high thermal conductivity constrain mission planners to steep entries, with high heat fluxes and pressures and short entry durations. The high entry conditions pose challenges for certification in existing ground based test facilities and the longer-term sustainability of CP will continue to pose challenges. NASA has decided to invest in new technology development rather than invest in reviving carbon phenolic. The HEEET project, funded by STMD is maturing a game changing Woven Thermal Protection System technology. HEEET is a capability development project and is not tied to a single mission or destination, therefore, it is challenging to complete ground testing needed to demonstrate a capability that is much broader than any single mission or destination would require. This presentation will status HEEET progress. Near term infusion target for HEEET is the upcoming New Frontiers (NF-4) class of competitively selected Science Mission Directorate (SMD) missions for which it is incentivized
Heatshield for Extreme Entry Environment Technology (HEEET) Enabling Missions Beyond Heritage Carbon Phenolic
This poster provides an overview of the requirements, design, development and testing of the 3D Woven TPS being developed under NASAs Heatshield for Extreme Entry Environment Technology (HEEET) project. Under this current program, NASA is working to develop a Thermal Protection System (TPS) capable of surviving entry into Venus or Saturn. A primary goal of the project is to build and test an Engineering Test Unit (ETU) to establish a Technical Readiness Level (TRL) of 6 for this technology by 2017
- …