741 research outputs found
Workgroup climates and employees' counterproductive work behaviours: A social-cognitive perspective
This research examines employees' anticipation of social and self-sanctions as a self-regulatory mechanism linking workgroup climates and counterproductive work behaviors (CWBs) and personality as a limit to these effects. A cross-level study with 158 employees from 26 workgroups demonstrated that in groups with a high compliance climate-a climate emphasizing the importance of complying with organizational rules-employees anticipate more social and self-sanctions, leading those low in conscientiousness and low in agreeableness to engage less frequently in CWBs. In contrast, a high relational climate-a climate emphasizing the importance of positive social relations over self-interest-indirectly unbridles the CWBs of these employees by alleviating the social and self-sanctions they anticipate for CWBs. Climates did not have indirect effects for employees high in agreeableness and high in conscientiousness. These findings elucidate why workgroup climates do not affect the CWBs of all members in the same way
Imaging Pulsed Laser Deposition oxide growth by in-situ Atomic Force Microscopy
To visualize the topography of thin oxide films during growth, thereby
enabling to study its growth behavior quasi real-time, we have designed and
integrated an atomic force microscope (AFM) in a pulsed laser deposition (PLD)
vacuum setup. The AFM scanner and PLD target are integrated in a single support
frame, combined with a fast sample transfer method, such that in-situ
microscopy can be utilized after subsequent deposition pulses. The in-situ
microscope can be operated from room temperature (RT) up to 700C and at
(process) pressures ranging from the vacuum base pressure of 10 mbar up
to 1 mbar, typical PLD conditions for the growth of oxide films. The
performance of this instrument is demonstrated by resolving unit cell height
surface steps and surface topography under typical oxide PLD growth conditions.Comment: 8 pages, 8 figure
Differential associations of personal and general just-world beliefs with the Five-Factor and HEXACO models of personality.
Recent literature evidences differential associations of personal and general just-world beliefs with constructs in the interpersonal domain. In line with this research, we examine the respective relationships of each just-world belief with the Five-Factor and the HEXACO models of personality in one representative sample of the working population of Switzerland and one sample of the general US population, respectively. One suppressor effect was observed in both samples: Neuroticism and emotionality was positively associated with general just-world belief, but only after controlling for personal just-world belief. In addition, agreeableness was positively and honesty-humility negatively associated with general just-world belief but unrelated to personal just-world belief. Conscientiousness was consistently unrelated to any of the just-world belief and extraversion and openness to experience revealed unstable coefficients across studies. We discuss these points in light of just-world theory and their implications for future research taking both dimensions into account
Subject-Specific Calculation of Left Atrial Appendage Blood-Borne Particle Residence Time Distribution in Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia that leads to thrombus formation,
mostly in the left atrial appendage (LAA). The current standard of stratifying stroke
risk, based on the CHA2DS2-VASc score, does not consider LAA morphology, and
the clinically accepted LAA morphology-based classification is highly subjective. The
aim of this study was to determine whether LAA blood-borne particle residence
time distribution and the proposed quantitative index of LAA 3D geometry can add
independent information to the CHA2DS2-VASc score. Data were collected from 16 AF
subjects. Subject-specific measurements included left atrial (LA) and LAA 3D geometry
obtained by cardiac computed tomography, cardiac output, and heart rate.We quantified
3D LAA appearance in terms of a novel LAA appearance complexity index (LAA-ACI).
We employed computational fluid dynamics analysis and a systems-based approach
to quantify residence time distribution and associated calculated variable (LAA mean
residence time, tm) in each subject. The LAA-ACI captured the subject-specific LAA 3D
geometry in terms of a single number. LAA tm varied significantly within a given LAA
morphology as defined by the current subjectivemethod and it was not simply a reflection
of LAA geometry/appearance. In addition, LAA-ACI and LAA tm varied significantly for a
given CHA2DS2-VASc score, indicating that these two indices of stasis are not simply
a reflection of the subjects’ clinical status. We conclude that LAA-ACI and LAA tm add
independent information to the CHA2DS2-VASc score about stasis risk and thereby can
potentially enhance its ability to stratify stroke risk in AF patients
Infectious titer determination of lentiviral vectors using a temporal immunological real-time imaging approach
The analysis of the infectious titer of the lentiviral vector samples obtained during upstream and downstream processing is of major importance, however, also the most challenging method to be performed. Currently established methods like flow cytometry or qPCR lack the capability of enabling high throughput sample processing while they require a lot of manual handling. To address this limitation, we developed an immunological real-time imaging method to quantify the infectious titer of anti-CD19 CAR lentiviral vectors with a temporal readout using the Incucyte® S3 live-cell analysis system. The infective titers determined with the Incucyte® approach when compared with the flow cytometry-based assay had a lower standard deviation between replicates and a broader linear range. A major advantage of the method is the ability to obtain titer results in real-time, enabling an optimal readout time. The presented protocol significantly decreased labor and increased throughput. The ability of the assay to process high numbers of lentiviral samples in a high throughput manner was proven by performing a virus stability study, demonstrating the effects of temperature, salt, and shear stress on LV infectivity
Exploring the path through which career adaptability increases job satisfaction and lowers work stress : the role of affect
The construct of career adaptability, or the ability to successfully manage one's career development and challenges, predicts several important outcomes; however, little is known about the
mechanisms contributing to its positive effects. The present study investigated the impact of career adaptability on job satisfaction and work stress, as mediated by individuals' affective states. Using a representative sample of 1671 individuals employed in Switzerland we hypothesized that, over time, career adaptability amplifies job satisfaction and attenuates work stress, through higher positive affect and lower negative affect, respectively. The data resulted from the first three waves of a longitudinal project on professional paths conducted in Switzerland. For each wave, participants completed a survey. Results of the 3-wave cross-lagged longitudinal model show that employees with higher career adaptability at Time 1 indeed experienced at Time 3 higher job satisfaction and lower work stress than those with lower career adaptability. The effect of career adaptability on job satisfaction and work stress was accounted for by negative affect: Individuals higher on career adaptability experienced less negative affect, which led to lower levels of stress and higher levels of job satisfaction, beyond previous levels of job satisfaction and work stress. Overall results support the conception of career adaptability as a self-regulatory resource that may promote a virtuous cycle in which individuals' evaluations of their resources to cope with the environment (i.e., career adaptability) shape their affective states, which in turn influence the evaluations of their job
Coincidence isometries of a shifted square lattice
We consider the coincidence problem for the square lattice that is translated
by an arbitrary vector. General results are obtained about the set of
coincidence isometries and the coincidence site lattices of a shifted square
lattice by identifying the square lattice with the ring of Gaussian integers.
To illustrate them, we calculate the set of coincidence isometries, as well as
generating functions for the number of coincidence site lattices and
coincidence isometries, for specific examples.Comment: 10 pages, 1 figure; paper presented at Aperiodic 2009 (Liverpool
Diversity, detection and exploitation: linking soil fungi and plant disease
Plant-associated fungi are incredibly diverse, comprising over a million species of mycorrhiza, endophytes, saprophytes and pathogens worldwide. This diverse fungal community is highly important for plant health. Many fungi are effective biocontrol agents that can kill or suppress fungal pathogens, with pathogen biocontrol found for both individual microorganisms and plant-associated fungal consortia. Meanwhile, increased plant community diversity aboveground corresponds to an increase in below-ground fungal community diversity, which contributes in turn to improved rhizosphere soil health and pathogen suppression. In this review, we discuss the role of fungal diversity in soil health and plant disease suppression and the various mechanisms by which mycorrhizal and endophytic fungi combat plant pathogenic fungi. We also discuss the array of diagnostic tools, both well-established and newly developed, which are revolutionising fungal pathogen detection and rhizosphere community analysis
Grain boundary energies and cohesive strength as a function of geometry
Cohesive laws are stress-strain curves used in finite element calculations to
describe the debonding of interfaces such as grain boundaries. It would be
convenient to describe grain boundary cohesive laws as a function of the
parameters needed to describe the grain boundary geometry; two parameters in 2D
and 5 parameters in 3D. However, we find that the cohesive law is not a smooth
function of these parameters. In fact, it is discontinuous at geometries for
which the two grains have repeat distances that are rational with respect to
one another. Using atomistic simulations, we extract grain boundary energies
and cohesive laws of grain boundary fracture in 2D with a Lennard-Jones
potential for all possible geometries which can be simulated within periodic
boundary conditions with a maximum box size. We introduce a model where grain
boundaries are represented as high symmetry boundaries decorated by extra
dislocations. Using it, we develop a functional form for the symmetric grain
boundary energies, which have cusps at all high symmetry angles. We also find
the asymptotic form of the fracture toughness near the discontinuities at high
symmetry grain boundaries using our dislocation decoration model.Comment: 12 pages, 19 figures, changed titl
- …