82 research outputs found

    N-(3-Oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-6-phenyl­imidazo[2,1-b][1,3]thia­zole-3-acetamide hemihydrate

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    The title compound, C21H22N4O2S2·0.5H2O, crystallizes with two mol­ecules in the asymmetric unit. The dihedral angles between the phenyl and imidazothiazole ring systems are 19.16 (9) and 21.37 (9)°. In the imidazothiazole ring systems, the cyclohexane rings adopt chair conformations, while the thiazole rings have distorted envelope conformations. The two mol­ecules are stabilized by intra­molecular N—H⋯O, O—H⋯O and C—H⋯S inter­actions and the crystal structure is stabilized by inter­molecular N—H⋯O, O—H⋯O, C—H⋯O and C—H⋯N inter­actions

    Medisinal Kimya Temel İlkeleri

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